Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.

Nagehan SALTAN, (Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Eskisehir, Türkiye)
Zeynep GÜLCAN, (Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Eskisehir, Türkiye)
Gökalp İŞCAN, (Anadolu Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Eskisehir, Türkiye)
Yavuz Bülent KÖSE (Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Eskisehir, Türkiye)
Biological Diversity and Conservation
4 0
Yıl: 2023 Cilt: 16 Sayı: 3 Sayfa Aralığı: 224 - 228 Metin Dili: İngilizce DOI: 10.46309/biodicon.2023.1270516 İndeks Tarihi: 22-12-2023

Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.

Öz:
The aim of this study is to measure the antioxidant and anticandidal efficiency of Pedicularis comosa var. acmodonta (Orobanchaceae). Using a spectrophotometric test on extracts from P.comosa var. acmodonta grown in Turkey, the antioxidant efficiency of the plant extracts was estimated by measuring the violet coloration in a methanol solution containing 1,1-diphenylpyryl hydrazil (DPPH·). In addition, the results of the anticandidal effect tests using the CLSI M27-A2 method are also included in this study. The 70% ethanol extract of P. comosa showed the highest antioxidant activity (0.143 mg/mL). According to the anticandidal activity test findings on five Candida species, it was determined that 70% ethanol extract of P. comosa inhibited C. utilis at a dose of 31.25 µg/mL (MIC).
Anahtar Kelime: anticandidal antioxidant Pedicularis Orobanchaceae.

Pedicularis comosa L. var. acmodonta Boiss. türünün antioksidan ve antikandidal etkilerinin belirlenmesi

Öz:
Bu çalışmanın amacı, Pedicularis comosa var. acmodonta (Orobanchaceae) türünün antioksidan ve antikandidal aktivitesini değerlendirmektir. Türkiye'de yetişen P. comosa var. acmodonta ekstreleri üzerinde bir spektrofotometrik test kullanılarak, bitki ekstrelerinin antioksidan aktivitesi, 1,1-difenilpiril hidrazil (DPPH·) içeren bir metanol solüsyonundaki mor rengin açılması ölçülerek değerlendirilmiştir. Ayrıca CLSI M27-A2 yöntemi kullanılarak yapılan antikandidal etki testlerinin sonuçları da bu çalışmada yer almaktadır. P. comosa'nın %70 etanol ekstresi en yüksek antioksidan aktiviteyi (0.143 mg/mL) göstermiştir. Beş Candida türü üzerinde yapılan antikandidal aktivite testi bulgularına göre P. comosa'nın %70 etanol ekstresinin C. utilis'i 31.25 µg/mL (MIC) dozunda inhibe ettiği belirlenmiştir.
Anahtar Kelime: antikandidal antioksidan Pedicularis Orobanchaceae.

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA SALTAN N, Gülcan Z, ISCAN G, Köse Y (2023). Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. , 224 - 228. 10.46309/biodicon.2023.1270516
Chicago SALTAN NAGEHAN,Gülcan Zeynep,ISCAN GOKALP,Köse Yavuz Bülent Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. (2023): 224 - 228. 10.46309/biodicon.2023.1270516
MLA SALTAN NAGEHAN,Gülcan Zeynep,ISCAN GOKALP,Köse Yavuz Bülent Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. , 2023, ss.224 - 228. 10.46309/biodicon.2023.1270516
AMA SALTAN N,Gülcan Z,ISCAN G,Köse Y Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. . 2023; 224 - 228. 10.46309/biodicon.2023.1270516
Vancouver SALTAN N,Gülcan Z,ISCAN G,Köse Y Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. . 2023; 224 - 228. 10.46309/biodicon.2023.1270516
IEEE SALTAN N,Gülcan Z,ISCAN G,Köse Y "Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.." , ss.224 - 228, 2023. 10.46309/biodicon.2023.1270516
ISNAD SALTAN, NAGEHAN vd. "Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.". (2023), 224-228. https://doi.org/10.46309/biodicon.2023.1270516
APA SALTAN N, Gülcan Z, ISCAN G, Köse Y (2023). Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. Biological Diversity and Conservation, 16(3), 224 - 228. 10.46309/biodicon.2023.1270516
Chicago SALTAN NAGEHAN,Gülcan Zeynep,ISCAN GOKALP,Köse Yavuz Bülent Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. Biological Diversity and Conservation 16, no.3 (2023): 224 - 228. 10.46309/biodicon.2023.1270516
MLA SALTAN NAGEHAN,Gülcan Zeynep,ISCAN GOKALP,Köse Yavuz Bülent Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. Biological Diversity and Conservation, vol.16, no.3, 2023, ss.224 - 228. 10.46309/biodicon.2023.1270516
AMA SALTAN N,Gülcan Z,ISCAN G,Köse Y Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. Biological Diversity and Conservation. 2023; 16(3): 224 - 228. 10.46309/biodicon.2023.1270516
Vancouver SALTAN N,Gülcan Z,ISCAN G,Köse Y Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.. Biological Diversity and Conservation. 2023; 16(3): 224 - 228. 10.46309/biodicon.2023.1270516
IEEE SALTAN N,Gülcan Z,ISCAN G,Köse Y "Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.." Biological Diversity and Conservation, 16, ss.224 - 228, 2023. 10.46309/biodicon.2023.1270516
ISNAD SALTAN, NAGEHAN vd. "Antioxidant and anticandidal effects of Pedicularis comosa L. var. acmodonta Boiss.". Biological Diversity and Conservation 16/3 (2023), 224-228. https://doi.org/10.46309/biodicon.2023.1270516
Sayfa Oluşturulma Tarihi
03-05-2024 9:51

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