ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY
Yıl: 2023 Cilt: 32 Sayı: 3 Sayfa Aralığı: 399 - 402 Metin Dili: İngilizce DOI: 10.34108/eujhs.1306589 İndeks Tarihi: 25-12-2023
ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY
Öz: Hidradenitis suppurativa (HS), is a chronic disease characterized by recurrent subcutaneous nodules, abscesses, and draining sinuses. Adalimumab is used for moderate to severe HS cases that do not respond to systemic treatments. The aim of our study was to evaluate the efficacy of adalimumab treatment in patients with HS who received treatment at our clinic. The medical records of patients aged 18 years and older who received adalimumab treatment for HS between 2016 and 2021 were retrospectively reviewed. When patients were evaluated in terms of Hidradenitis Suppurativa Clinical Response (HISCR) at the end of 3 months, 6 (31.6%) patients had achieved HISCR within 3 months. After 6 months of treatment, an additional 9 (47.4%) patients had reached the HISCR endpoint. At the end of 6 months, no response was observed in 4 patients (21.1%). Based on the data obtained from the study, adalimumab is considered to be an effective and safe treatment method for moderate to severe HS patients.
Anahtar Kelime: HİDRADENİTİS SÜPÜRATİVADA ADALİMUMAB TEDAVİSİNİN ETKİNLİĞİNİN DEĞERLENDİRİLMESİ: TEK MERKEZLİ BİR ÇALIŞMA
Öz: Hidradenitis süpürativa (HS), deri altında nodüller, apseler ve drene olan sinüslerin görülebildiği tekrarlayıcı bir hastalıktır. Adalimumab, sistemik tedavilere yanıt vermeyen orta ila şiddetli HS için kullanılmaktadır. Çalışmamızda kliniğimizde adalimumab tedavisi alan HS hastalarında etkinliği değerlendirmeyi amaçladık. Çalışmaya kliniğimize 2016-2021 yılları arasında başvuran, 18 yaşından büyük HS nedeniyle adalimumab tedavisi alan hastaların dosyaları retrospektif olarak taranmıştır. Hastalar 3 ay sonunda Hidradenitis Suppurativa Clinical Response (HiSCR) ile değerlendirildiğinde 6 (%31.6) hasta HiSCR’ye ulaşmıştı. Altı aylık tedavi sonrasında 9 (%47.4) hasta daha HiSCR değerine ulaşmıştı. Altı ayın sonunda 4 hastada (%21.1) tedaviye herhangi bir yanıt elde edilmedi.Çalışmadan elde edilen veriler neticesinde orta-şiddetli HS hastalarında adalimumabın etkili ve güvenli bir tedavi yöntemi olduğu düşünülmüştür.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ÖKSÜM SOLAK E (2023). ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. , 399 - 402. 10.34108/eujhs.1306589 |
| Chicago | ÖKSÜM SOLAK EDA ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. (2023): 399 - 402. 10.34108/eujhs.1306589 |
| MLA | ÖKSÜM SOLAK EDA ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. , 2023, ss.399 - 402. 10.34108/eujhs.1306589 |
| AMA | ÖKSÜM SOLAK E ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. . 2023; 399 - 402. 10.34108/eujhs.1306589 |
| Vancouver | ÖKSÜM SOLAK E ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. . 2023; 399 - 402. 10.34108/eujhs.1306589 |
| IEEE | ÖKSÜM SOLAK E "ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY." , ss.399 - 402, 2023. 10.34108/eujhs.1306589 |
| ISNAD | ÖKSÜM SOLAK, EDA. "ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY". (2023), 399-402. https://doi.org/10.34108/eujhs.1306589 |
| APA | ÖKSÜM SOLAK E (2023). ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. Sağlık Bilimleri Dergisi, 32(3), 399 - 402. 10.34108/eujhs.1306589 |
| Chicago | ÖKSÜM SOLAK EDA ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. Sağlık Bilimleri Dergisi 32, no.3 (2023): 399 - 402. 10.34108/eujhs.1306589 |
| MLA | ÖKSÜM SOLAK EDA ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. Sağlık Bilimleri Dergisi, vol.32, no.3, 2023, ss.399 - 402. 10.34108/eujhs.1306589 |
| AMA | ÖKSÜM SOLAK E ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. Sağlık Bilimleri Dergisi. 2023; 32(3): 399 - 402. 10.34108/eujhs.1306589 |
| Vancouver | ÖKSÜM SOLAK E ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY. Sağlık Bilimleri Dergisi. 2023; 32(3): 399 - 402. 10.34108/eujhs.1306589 |
| IEEE | ÖKSÜM SOLAK E "ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY." Sağlık Bilimleri Dergisi, 32, ss.399 - 402, 2023. 10.34108/eujhs.1306589 |
| ISNAD | ÖKSÜM SOLAK, EDA. "ASSESSMENT OF THE EFFICACY OF ADALIMUMAB TREATMENT IN HIDRADENITIS SUPPURATIVA: A SINGLE-CENTER STUDY". Sağlık Bilimleri Dergisi 32/3 (2023), 399-402. https://doi.org/10.34108/eujhs.1306589 |
