Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters

Gezegen, Hayreddin

doi:10.17776/csj.1341173

Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters

Hayreddin GEZEGEN (Sivas Cumhuriyet Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü, Sivas, Türkiye)

Cumhuriyet Science Journal

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Yıl: 2023 Cilt: 44 Sayı: 4 Sayfa Aralığı: 678 - 686 Metin Dili: İngilizce DOI: 10.17776/csj.1341173 İndeks Tarihi: 03-01-2024

Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters

Öz:

Chromene derivatives are among the natural compounds and they can also be easily obtained synthetically. They are one of the most commonly used skeletons in heterocyclic chemistry. Chromene derivatives are used in the cosmetic and pigment industries as well as having a wide spectrum of biological activity. Synthesis of chromene derivatives and their application areas is a current topic. In this study, it is aimed to synthesis and characterization of new chromene derivatives by catalysis of molecular iodine starting from 1,5-diol derivatives with chiral centers. In this context, 8 new 2,4-diaryloctahydro-2H-chromene derivatives were synthesized in high yields and their structure determinations were made by spectroscopic methods (1H-NMR, 13C-NMR, 2D-NMR, GCMS and FTIR) and their stereochemistry was determined.

Anahtar Kelime: Chalcone 1 5-Diol Chromene Iodine.

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Gezegen H (2023). Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. , 678 - 686. 10.17776/csj.1341173
Chicago	Gezegen Hayreddin Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. (2023): 678 - 686. 10.17776/csj.1341173
MLA	Gezegen Hayreddin Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. , 2023, ss.678 - 686. 10.17776/csj.1341173
AMA	Gezegen H Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. . 2023; 678 - 686. 10.17776/csj.1341173
Vancouver	Gezegen H Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. . 2023; 678 - 686. 10.17776/csj.1341173
IEEE	Gezegen H "Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters." , ss.678 - 686, 2023. 10.17776/csj.1341173
ISNAD	Gezegen, Hayreddin. "Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters". (2023), 678-686. https://doi.org/10.17776/csj.1341173

APA	Gezegen H (2023). Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. Cumhuriyet Science Journal, 44(4), 678 - 686. 10.17776/csj.1341173
Chicago	Gezegen Hayreddin Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. Cumhuriyet Science Journal 44, no.4 (2023): 678 - 686. 10.17776/csj.1341173
MLA	Gezegen Hayreddin Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. Cumhuriyet Science Journal, vol.44, no.4, 2023, ss.678 - 686. 10.17776/csj.1341173
AMA	Gezegen H Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. Cumhuriyet Science Journal. 2023; 44(4): 678 - 686. 10.17776/csj.1341173
Vancouver	Gezegen H Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters. Cumhuriyet Science Journal. 2023; 44(4): 678 - 686. 10.17776/csj.1341173
IEEE	Gezegen H "Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters." Cumhuriyet Science Journal, 44, ss.678 - 686, 2023. 10.17776/csj.1341173
ISNAD	Gezegen, Hayreddin. "Synthesis and Characterization of Novel 2,4-Diaryloctahydro-2H-Chromene Derivatives with Four Stereocenters". Cumhuriyet Science Journal 44/4 (2023), 678-686. https://doi.org/10.17776/csj.1341173