Yıl: 2023 Cilt: 8 Sayı: 2 Sayfa Aralığı: 134 - 144 Metin Dili: Türkçe DOI: 10.33484/sinopfbd.1322953 İndeks Tarihi: 03-01-2024

Manyetik Kantilever ile IgG Antikorlarının Tespiti

Öz:
Bu çalışmada, IgG antikorlarını algılamak için kantilever olarak $Fe_{40}Ni_{38}Mo_{4}B_{18}$ amorf ferromanyetik şerit kullanılmıştır. Sensör yüzeyi IgG algılaması için fonksiyonel hale getirilmiş ve daha sonra yapılan ölçümlerde ppm ya da ng mertebesinde IgG algılaması yapılmıştır.
Anahtar Kelime: Kantilever amorf ferromanyetk şerit IgG

Detection of IgG Antibodies with Magnetic Cantilever

Öz:
In this study, $Fe_{40}Ni_{38}Mo_{4}B_{18}$ amorphous ferromagnetic ribbon was used as cantilever to detect IgG antibodies. The sensor surface was functionalized for IgG detection, and IgG detection was performed at the level of ppm or ng.
Anahtar Kelime: Cantilever amorphous ferromagnetic ribbon IgG

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • Wang Q, Jing, J. Y., & Wang B.T. (2019). Highly sensitive SPR biosensor based on graphene oxide and staphylococcal protein a co-modified TFBG for human IgG detection. IEEE Transactions on Instrumentation and Measurement. 68, 3350-3357. https://doi.org/10.1109/TIM.2018.2875961
  • Liu H. C., Ponniah G., Zhang H. M., Nowak C., Neill A., Gonzalez-Lopez N., Patel R., Cheng G. L., Kita A. Z., & Andrien B. (2014). In vitro and in vivo modifications of recombinant and human IgG antibodies. Affiliated with the Antibody Society, 6, 1145-1154. https://doi.org/10.4161/mabs.29883
  • Valenzuela N. M., & Schaub, S. (2018). The biology of IgG subclasses and their clinical relevance to transplantation. Transplantation, 102, 7-13. https://doi.org/10.1097/TP.0000000000001816
  • Marchionatti, A., Woodhall, M., Waters, P. J., & Sato, D. K. (2020). Detection of MOG-IgG by cell-based assay: moving from discovery to clinical practice. Neurological Sciences, 42, 73-80. https://doi.org/10.1007/s10072-020-04828-1
  • Sharma, D., & Tripathi, N. (2017). Microcantilever: an efficient tool for biosensing applications. International Journal of Intelligent Systems and Applications, 10, 63-74. https://doi.org/10.5815/ijisa.2017.10.08
  • Noh, J. W. (2009). In-plane all-photonic transduction method for silicon photonic microcantilever. PhD Thesis, Brigham Young University.
  • Binnig, G., Quate, C. F., & Gerber, C. (1986). Atomic force microscope. Physical Review Letters, 56, 930-934. https://doi.org/10.1103/PhysRevLett.56.930
  • Berger, R., Gerber, C., Gimzewski, J. K., Meyer, E., & Guntherodt, H. J. (1996). Thermal analysis using a micromechanical calorimeter, Applied Physics Letters, 69, 40-42. https://doi.org/10.1063/1.118111
  • Barnes, J. R., Stephenson, R. J., Welland, M. E., Gerber, C., & Gimzewski, J. K., (1994). Photothermal spectroscopy with femtojoule sensitivity using a micromechanical device. Nature, 372. 79-81, https://doi.org/10.1038/372079a0
  • Arakawa, E. T., Lavrik, N. V., Rajic, S., & Datskos, P. G. (2003). Detection and differentiation of biological species using microcalorimetric spectroscopy. Ultramicroscopy, 97, 459-465. https://doi.org/10.1016/S0304-3991(03)00074-3
  • Dohn, S., Sandberg, R., Svendsen, W., & Boisen, A. (2005). Enhanced functionality of cantilever based mass sensors using higher modes. Applied Physics Letters, 86, 233501-233503. https://doi.org/10.1063/1.1948521
  • Hosaka, S., Chiyoma, T., Ikeuchi, A., Okano, H., Sone, H., & Izumi, T. (2006). Possibility of a femtogram mass biosensor using a self-sensing cantilever. Current Applied Physics, 6, 384-388. https://doi.org/10.1016/j.cap.2005.11.024
  • Spletzer, M., Raman, A., Wu, A. Q., Xu, X., & Reifenberger, R., (2006). Ultrasensitive mass sensing using mode localization in coupled microcantilevers. Applied Physics Letters, 88, 254102-254103. https://doi.org/10.1063/1.2216889
  • Sharos, L. B., Raman, A., Crittenden, S., & Reifenberger, R., (2004). Enhanced mass sensing using torsional and lateral resonances in microcantilevers. Applied Physics Letters, 84, 4638-4640. https://doi.org/10.1063/1.1759379
  • Cowburn, R. P., Moulin, A. M., & Welland, M. E. (1997). High sensitivity measurement of magnetic fields using microcantilevers. Applied Physics Letters, 71, 2202-2204. https://doi.org/10.1063/1.119381
  • Ohmichi, E., & Osada, T. (2002). Torque magnetometry in pulsed magnetic fields with use of a commercial microcantilever, Review of Scientific Instruments, 73, 3022-3026. https://doi.org/10.1063/1.1491999
  • Liu, J., & Li, X. (2007). A piezoresistive microcantilever magnetic-field sensor with on-chip self-calibration function integrated. Microelectronics Journal, 38, 210-215. https://doi.org/10.1016/j.mejo.2006.11.015
  • Thundat, T., Wachter, E. A., Sharp, S. L., & Warmack, R. J. (1995). Detection of mercury-vapor using resonating microcantilevers. Applied Physics Letters, 66, 1695-1697. https://doi.org/10.1063/1.113896
  • Fritz, J., Baller, M. K., Lang, H. P., Rothuizen, H., Vettiger, P., Meyer, E., Guumlntherodt, H.-J., Gerber, C., & Gimzewski, J. K. (2000). Translating biomolecular recognition into nanomechanics. Science, 288, 316-318. https://doi.org/10.1126/science.288.5464.316
  • Wu, G., Datar, R. H., Hansen, K. M., Thundat, T., Cote, R. J., & Majumdar, A., (2001). Bioassay of prostate-specific antigen (PSA) using microcantilevers. Nature Biotechnology, 19, 856-860. https://doi.org/10.1038/nbt0901-856
  • Bashir, R., Hilt, J. Z., Elibol, O., Gupta, A., & Peppas, N. A. (2002). Micromechanical cantilever as an ultrasensitive pH microsensor. Applied Physics Letters, 81, 3091-3093. https://doi.org/10.1063/1.1514825
  • Moulin, A. M., O'Shea, S. J., & Welland, M. E. (2001). Microcantilever-based biosensors. Ultramicroscopy, 82, 23-31. https://doi.org/10.1016/S0304-3991(99)00145-X
  • Hansen, K. M., & Thundat, T. (2005). Microcantilever biosensors, Methods, 37, 57-64.
  • Waggoner, P. S., & Craighead, H. G. (2007). Micro- and nanomechanical sensors for environmental, chemical, and biological detection. Lab on a Chip, 7, 1238-1255. https://doi.org/10.1039/B707401H
  • Raiteri, R., Grattarola, M., Butt, H.-J., & Skládal, P. (2001). Micromechanical cantilever-based biosensors. Sensors and Actuators B: Chemical, 79, 115-126. https://doi.org/10.1016/S0925-4005(01)00856-5
  • Zhang, J., Lang, H. P., Huber, F., Bietsch, A., Grange, W., Certa, U., McKendry, R., Guntherodt, H. J., Hegner, M., & Gerber, C. (2006). Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA. Nature Nanotechnology, 1, 214-220. https://doi.org/10.1038/nnano.2006.134
  • Fadel, L., Lochon, F., Dufour, I., & Francais, O. (2004). Chemical sensing: millimeter size resonant microcantilever performance. Journal of Micromechanics and Microengineering, 14, 23-30. https://doi.org/10.1088/0960-1317/14/9/004
  • Atalay, S., Kolat, V. S., Atalay, F. E., Bayri, N., Kaya, H., & Izgi, T. (2018). Magnetoelastic sensor for magnetic nanoparticle detection. Journal of Magnetism and Magnetic Materials, 465, 151-155. https://doi.org/10.1016/j.jmmm.2018.05.108
APA İnan O, Dik G, Ulu A, Ates B, ATALAY S (2023). Manyetik Kantilever ile IgG Antikorlarının Tespiti. , 134 - 144. 10.33484/sinopfbd.1322953
Chicago İnan Orhan Orçun,Dik Gamze,Ulu Ahmet,Ates Burhan,ATALAY Selçuk Manyetik Kantilever ile IgG Antikorlarının Tespiti. (2023): 134 - 144. 10.33484/sinopfbd.1322953
MLA İnan Orhan Orçun,Dik Gamze,Ulu Ahmet,Ates Burhan,ATALAY Selçuk Manyetik Kantilever ile IgG Antikorlarının Tespiti. , 2023, ss.134 - 144. 10.33484/sinopfbd.1322953
AMA İnan O,Dik G,Ulu A,Ates B,ATALAY S Manyetik Kantilever ile IgG Antikorlarının Tespiti. . 2023; 134 - 144. 10.33484/sinopfbd.1322953
Vancouver İnan O,Dik G,Ulu A,Ates B,ATALAY S Manyetik Kantilever ile IgG Antikorlarının Tespiti. . 2023; 134 - 144. 10.33484/sinopfbd.1322953
IEEE İnan O,Dik G,Ulu A,Ates B,ATALAY S "Manyetik Kantilever ile IgG Antikorlarının Tespiti." , ss.134 - 144, 2023. 10.33484/sinopfbd.1322953
ISNAD İnan, Orhan Orçun vd. "Manyetik Kantilever ile IgG Antikorlarının Tespiti". (2023), 134-144. https://doi.org/10.33484/sinopfbd.1322953
APA İnan O, Dik G, Ulu A, Ates B, ATALAY S (2023). Manyetik Kantilever ile IgG Antikorlarının Tespiti. Sinop Üniversitesi fen bilimleri dergisi, 8(2), 134 - 144. 10.33484/sinopfbd.1322953
Chicago İnan Orhan Orçun,Dik Gamze,Ulu Ahmet,Ates Burhan,ATALAY Selçuk Manyetik Kantilever ile IgG Antikorlarının Tespiti. Sinop Üniversitesi fen bilimleri dergisi 8, no.2 (2023): 134 - 144. 10.33484/sinopfbd.1322953
MLA İnan Orhan Orçun,Dik Gamze,Ulu Ahmet,Ates Burhan,ATALAY Selçuk Manyetik Kantilever ile IgG Antikorlarının Tespiti. Sinop Üniversitesi fen bilimleri dergisi, vol.8, no.2, 2023, ss.134 - 144. 10.33484/sinopfbd.1322953
AMA İnan O,Dik G,Ulu A,Ates B,ATALAY S Manyetik Kantilever ile IgG Antikorlarının Tespiti. Sinop Üniversitesi fen bilimleri dergisi. 2023; 8(2): 134 - 144. 10.33484/sinopfbd.1322953
Vancouver İnan O,Dik G,Ulu A,Ates B,ATALAY S Manyetik Kantilever ile IgG Antikorlarının Tespiti. Sinop Üniversitesi fen bilimleri dergisi. 2023; 8(2): 134 - 144. 10.33484/sinopfbd.1322953
IEEE İnan O,Dik G,Ulu A,Ates B,ATALAY S "Manyetik Kantilever ile IgG Antikorlarının Tespiti." Sinop Üniversitesi fen bilimleri dergisi, 8, ss.134 - 144, 2023. 10.33484/sinopfbd.1322953
ISNAD İnan, Orhan Orçun vd. "Manyetik Kantilever ile IgG Antikorlarının Tespiti". Sinop Üniversitesi fen bilimleri dergisi 8/2 (2023), 134-144. https://doi.org/10.33484/sinopfbd.1322953