TY - JOUR TI - Interaction of Ti-6Al-7Nb alloy with simulated body fluid; a preliminary biocompatibility investigation AB - The current study aims to investigate the interaction of Ti-6Al-7Nb with simulated body fluid (SBF) in order to apply a preliminary biocompatibility investigation of this novel biomedical alloy, promising for orthopedic applications. Results of the static immersion tests conducted in SBF at body temperature demonstrated that Ca-P rich structures form on the Ti-6Al-7Nb alloy surfaces and the oxide layer formation-dissolution cycle reaches a stable state during immersion. Ion release levels were mostly below critical values except for the initial Al ion release level, which indicated the need for the presence of a stable protective layer on the alloy surface. The second set of static immersion experiments conducted in densified SBF demonstrated that, such a protective layer can rapidly form by biomimetic coating if followed by a preliminary surface treatment. Overall, Ti-6Al-7Nb alloys layers exhibit promising biocompatibility for orthopedic applications, especially with the presence of a stable protective layer. AU - Culfa, Şura AU - Toker, Sidika Mine DO - 10.51753/flsrt.1294479 PY - 2023 JO - Frontiers in Life Sciences and Related Technologies (Online) VL - 4 IS - 3 SN - 2718-062X SP - 111 EP - 117 DB - TRDizin UR - http://search/yayin/detay/1216886 ER -