Yıl: 2023 Cilt: 53 Sayı: 6 Sayfa Aralığı: 1863 - 1869 Metin Dili: İngilizce DOI: 10.55730/1300-0144.5756 İndeks Tarihi: 18-01-2024

Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?

Öz:
Background and aim: There are over 60,000 hemodialysis (HD) patients in Türkiye, and the number of patients is increasing yearly. Dialysate flow rate (Qd) is a factor in HD adequacy. Approximately 150 L of water are consumed per session to prepare the dialysate. We aimed to investigate whether HD effectiveness can be achieved at a low Qd in different patient groups for the purpose of saving water. Materials and methods: This prospective study included 81 HD patients from 2 centers. The patients underwent an aggregate total of 486 HD sessions, including 3 sessions at a Qd of 500 mL/min and 3 sessions at a Qd of 300 mL/min for each patient. We used online Kt/V readings recorded at the end of each dialysis session to compare the effectiveness of these 2 types of HD session performed at a different Qd. Results: The online Kt/V readings were similar between the standard (500) and low (300) Qd HD (1.51 ± 0.41 and 1.49 ± 0.44, respectively, p = 0.069). In the subgroup analyses, men had higher online Kt/V values at the standard Qd compared to the low Qd (1.35 ± 0.30 and 1.30 ± 0.32, respectively, p = 0.019), but the Kt/V values were not different for women. While the low Qd did not reduce online Kt/V in patients using small surface area dialysis membranes (1.75 ± 0.35 for 300 Qd and 1.75 ± 0.32 for 500 Qd, p = 0.931), it was associated with reduced online Kt/V in patients using large surface area dialysis membranes (1.12 ± 0.25 for 300 Qd and 1.17 ± 0.24 for 500 Qd, p = 0.006). The low Qd did not result in differences in online Kt/V among low-weight patients. However, online Kt/V values were better with the standard Qd in patients weighing 65 kg and above. Conclusion: In our study, dialysis adequacy at a reduced dialysate flow was not inferior for women, patients with low body weight, or patients using small surface area membranes. Individualized HD at a reduced Qd of 300 mL/min in eligible patients can save 48 L of water per HD session and an average of 7500 L of water per year.
Anahtar Kelime: Hemodialysis dialysis adequacy dialysate flow rate online Kt/V

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Aktaş A, ÖZER H, Baloglu I, Tonbul H, GÜNEY I, SELÇUK N (2023). Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. , 1863 - 1869. 10.55730/1300-0144.5756
Chicago Aktaş Ali,ÖZER Hakan,Baloglu Ismail,Tonbul Halil Zeki,GÜNEY IBRAHIM,SELÇUK Nedim Yılmaz Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. (2023): 1863 - 1869. 10.55730/1300-0144.5756
MLA Aktaş Ali,ÖZER Hakan,Baloglu Ismail,Tonbul Halil Zeki,GÜNEY IBRAHIM,SELÇUK Nedim Yılmaz Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. , 2023, ss.1863 - 1869. 10.55730/1300-0144.5756
AMA Aktaş A,ÖZER H,Baloglu I,Tonbul H,GÜNEY I,SELÇUK N Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. . 2023; 1863 - 1869. 10.55730/1300-0144.5756
Vancouver Aktaş A,ÖZER H,Baloglu I,Tonbul H,GÜNEY I,SELÇUK N Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. . 2023; 1863 - 1869. 10.55730/1300-0144.5756
IEEE Aktaş A,ÖZER H,Baloglu I,Tonbul H,GÜNEY I,SELÇUK N "Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?." , ss.1863 - 1869, 2023. 10.55730/1300-0144.5756
ISNAD Aktaş, Ali vd. "Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?". (2023), 1863-1869. https://doi.org/10.55730/1300-0144.5756
APA Aktaş A, ÖZER H, Baloglu I, Tonbul H, GÜNEY I, SELÇUK N (2023). Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. Turkish Journal of Medical Sciences, 53(6), 1863 - 1869. 10.55730/1300-0144.5756
Chicago Aktaş Ali,ÖZER Hakan,Baloglu Ismail,Tonbul Halil Zeki,GÜNEY IBRAHIM,SELÇUK Nedim Yılmaz Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. Turkish Journal of Medical Sciences 53, no.6 (2023): 1863 - 1869. 10.55730/1300-0144.5756
MLA Aktaş Ali,ÖZER Hakan,Baloglu Ismail,Tonbul Halil Zeki,GÜNEY IBRAHIM,SELÇUK Nedim Yılmaz Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. Turkish Journal of Medical Sciences, vol.53, no.6, 2023, ss.1863 - 1869. 10.55730/1300-0144.5756
AMA Aktaş A,ÖZER H,Baloglu I,Tonbul H,GÜNEY I,SELÇUK N Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. Turkish Journal of Medical Sciences. 2023; 53(6): 1863 - 1869. 10.55730/1300-0144.5756
Vancouver Aktaş A,ÖZER H,Baloglu I,Tonbul H,GÜNEY I,SELÇUK N Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?. Turkish Journal of Medical Sciences. 2023; 53(6): 1863 - 1869. 10.55730/1300-0144.5756
IEEE Aktaş A,ÖZER H,Baloglu I,Tonbul H,GÜNEY I,SELÇUK N "Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?." Turkish Journal of Medical Sciences, 53, ss.1863 - 1869, 2023. 10.55730/1300-0144.5756
ISNAD Aktaş, Ali vd. "Individualized hemodialysis: Is similar hemodialysis adequacy possible using less water?". Turkish Journal of Medical Sciences 53/6 (2023), 1863-1869. https://doi.org/10.55730/1300-0144.5756