The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis
Yıl: 2024 Cilt: 16 Sayı: 1 Sayfa Aralığı: 83 - 87 Metin Dili: İngilizce DOI: 10.18521/ktd.1394091 İndeks Tarihi: 02-04-2024
The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis
Öz: Objective: In patients with juvenile idiopathic arthritis (JIA), bone metabolism may be negatively affected due to both the activity of the disease and the medications used. Our study aimed to investigate the necessity of evaluating 25 hydroxyvitamin D (25 (OH) Vit D), calcium (Ca), phosphorus (P), alkaline phosphatase (ALP) levels and possible related factors in the follow-up of patients diagnosed with JIA. Method: The records of 68 patients with JIA were retrospectively evaluated. Disease subtypes, medications used, and whether they were in remission or active disease were reviewed. Results: 25 OH Vit D levels were low in 14.7% of patients with JIA compared to the control group. 66.6% of the patients with systemic arthritis had high ALP levels. 25 OH Vit D level was low in 16.6% of steroid users, and Vitamin D level was low in 55.5% of the patients in the active disease group. It was determined that patients in the active disease group had the highest ALP and lowest vitamin D levels compared to patients in remission with and without medication. Conclusion: Bone metabolism in patients with JIA is negatively affected. Since vitamin D plays a crucial role in bone metabolism, it was emphasized that vitamin D levels should be evaluated especially during active disease and supplements should be provided for patients with low vitamin D levels.
Anahtar Kelime: Juvenil İdiyopatik Artrit Tanılı Çocuklarda 25 Hidroksivitamin D Düzey Takibinin Önemi
Öz: Amaç: Juvenil idiyopatik artrit (JİA)’li hastalarda gerek hastalığın aktivitesi gerekse kullanılan ilaçlar nedeni ile kemik metabolizması olumsuz etkilenebilir. Çalışmamızda JİA tanılı hastaların takibinde 25 hidroksivitamin D (25 (OH) Vit D), kalsiyum (Ca), fosfor (P), alkalen fosfataz (ALP) düzeyleri ve ilişkili olabilecek faktörlerin değerlendirilmesinin gerekliliğini araştırmak amaçlandı Metod: JİA tanılı 68 hastanın kayıtları retrospektif olarak değerlendirildi. Hastalık alt tipleri, remisyon durumu, kullanılan ilaçlar incelendi. Bulgular: Kontrol grubuna kıyasla JİA hastalarının %14,7’sinde vitamin D düzeyinin düşük olduğu bulundu. Sistemik artriti olan hastaların %66,6’sında ALP düzeyinin yüksek olduğu saptandı. Steroid kullananların %16,6’sında vitamin D düzeyi düşük bulundu. İlaçlı ve ilaçsız remisyondaki hastalarla kontrol grubu arasında biyokimyasal parametreler açısından fark yoktu. Aktif hastalık grubundaki hastaların %55,5’inde vitamin D düzeyleri düşük saptandı. Aktif hastalık grubundaki hastaların, ilaçlı ve ilaçsız remisyondaki hastalar ile karşılaştırıldığında, en yüksek ALP ve en düşük vitamin D düzeyine sahip oldukları saptandı. Sonuç: JİA’lı hastalarda kemik metabolizması olumsuz etkilenmektedir. D vitamininin kemik metabolizması üzerinde önemli rol oynaması nedeni ile bu hasta grubunda özellikle aktif hastalık sırasında vitamin D düzeylerinin bakılması ve D vitamini düşük saptanan hastalara vitamin D desteği verilmesi gerekliliği vurgulandı.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Yildirim U, ERGÜVEN M (2024). The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. , 83 - 87. 10.18521/ktd.1394091 |
| Chicago | Yildirim Ulku Miray,ERGÜVEN MÜFERET The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. (2024): 83 - 87. 10.18521/ktd.1394091 |
| MLA | Yildirim Ulku Miray,ERGÜVEN MÜFERET The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. , 2024, ss.83 - 87. 10.18521/ktd.1394091 |
| AMA | Yildirim U,ERGÜVEN M The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. . 2024; 83 - 87. 10.18521/ktd.1394091 |
| Vancouver | Yildirim U,ERGÜVEN M The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. . 2024; 83 - 87. 10.18521/ktd.1394091 |
| IEEE | Yildirim U,ERGÜVEN M "The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis." , ss.83 - 87, 2024. 10.18521/ktd.1394091 |
| ISNAD | Yildirim, Ulku Miray - ERGÜVEN, MÜFERET. "The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis". (2024), 83-87. https://doi.org/10.18521/ktd.1394091 |
| APA | Yildirim U, ERGÜVEN M (2024). The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. KONURALP TIP DERGİSİ, 16(1), 83 - 87. 10.18521/ktd.1394091 |
| Chicago | Yildirim Ulku Miray,ERGÜVEN MÜFERET The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. KONURALP TIP DERGİSİ 16, no.1 (2024): 83 - 87. 10.18521/ktd.1394091 |
| MLA | Yildirim Ulku Miray,ERGÜVEN MÜFERET The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. KONURALP TIP DERGİSİ, vol.16, no.1, 2024, ss.83 - 87. 10.18521/ktd.1394091 |
| AMA | Yildirim U,ERGÜVEN M The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. KONURALP TIP DERGİSİ. 2024; 16(1): 83 - 87. 10.18521/ktd.1394091 |
| Vancouver | Yildirim U,ERGÜVEN M The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis. KONURALP TIP DERGİSİ. 2024; 16(1): 83 - 87. 10.18521/ktd.1394091 |
| IEEE | Yildirim U,ERGÜVEN M "The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis." KONURALP TIP DERGİSİ, 16, ss.83 - 87, 2024. 10.18521/ktd.1394091 |
| ISNAD | Yildirim, Ulku Miray - ERGÜVEN, MÜFERET. "The Importance of 25 Hydroxyvitamin D Level Monitoring in Children Diagnosed with Juvenile Idiopathic Arthritis". KONURALP TIP DERGİSİ 16/1 (2024), 83-87. https://doi.org/10.18521/ktd.1394091 |
