Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer

Yıl: 2024 Cilt: 13 Sayı: 1 Sayfa Aralığı: 35 - 39 Metin Dili: İngilizce DOI: 10.46810/tdfd.1394182 İndeks Tarihi: 21-05-2024

Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer

Öz:
Prostate cancer is one of the most common types of cancer in men. It usually grows slowly and may not show obvious symptoms at first. Prostate cancer can be diagnosed by symptoms or by a doctor performing certain tests during routine health checkups. These tests include physical examination, PSA (Prostate Specific Antigen) Test, biopsy, imaging techniques, and Gleason score. In addition, Fourier transform infrared spectroscopy (FT-IR) is an analysis method used for prostate cancer diagnosis. This study aims to demonstrate FT-IR spectroscopy as an alternative method to other diagnostic methods in the diagnosis of prostate cancer. The FT-IR spectroscopy method is used to examine the molecular structure of samples. For prostate cancer diagnosis, FT-IR spectroscopy can be used to identify molecular changes in prostate tissue and identify characteristics by which cancerous cells differ from healthy cells. FT-IR spectroscopy is based on spectral data obtained by exposing samples to infrared radiation. These spectral data are based on properties associated with the movements of the molecules contained in the samples, such as vibration, rotation and bending. Molecular changes caused by diseases such as prostate cancer may be evident in these spectral data. These changes can provide information about the presence or stage of cancerous cells. Data obtained using FT-IR spectroscopy is processed with statistical analysis methods. These analyses are used to identify molecular differences between cancerous and healthy prostate tissues. In this way, FTIR spectroscopy can help obtain sensitive and accurate results in the diagnosis of prostate cancer.
Anahtar Kelime: FT-IR Spectroscopy Prostate cancer Diagnostic methods Chemometric Analysis

Prostat Kanseri Tanısında Alternatif Bir Yöntem Olarak Fourier Dönüşümlü Kızılötesi (FT-IR) Spektroskopisi ve Kemometrik Analiz Yönteminin İncelenmesi

Öz:
Prostat kanseri, erkeklerde en sık görülen kanser türlerinden biridir. Genellikle yavaş büyür ve ilk başlarda belirgin belirtiler göstermeyebilir. Prostat kanseri teşhisi, belirtiler veya rutin sağlık kontrolleri sırasında doktorun belirli testler yapmasıyla konulabilir. Bu testler; Fiziki muayene, PSA (Prostat Spesifik Antijen) Testi, biyopsi, görüntüleme teknikleri, gleason skorudur. Bunların yanısıra, Fourier dönüşümlü kızılötesi spektroskopisi (FT-IR), prostat kanseri teşhisi için kullanılan bir analiz yöntemidir. Bu çalışma da prostat kanseri teşhisinde diğer teşhis yöntemlerinde alternatif bir yöntem olarak FT-IR spektroskopisini göstermektir. FT-IR spektroskopi yöntemi, örneklerin moleküler yapısını incelemek için kullanılır. Prostat kanseri teşhisi için FT-IR spektroskopisi, prostat dokusundaki moleküler değişiklikleri belirlemek ve kanserli hücrelerin sağlıklı hücrelerden farklı olduğu özellikleri tespit etmek amacıyla kullanılabilir. FT-IR spektroskopisi, örneklerin infrared radyasyona maruz bırakılmasıyla elde edilen spektral verilere dayanır. Bu spektral veriler, örneklerin içerdiği moleküllerin vibrasyon, rotasyon ve bükülme gibi hareketleriyle ilişkilendirilmiş özelliklere dayanır. Prostat kanseri gibi hastalıkların neden olduğu moleküler değişiklikler, bu spektral verilerde belirgin olabilir. Bu değişiklikler, kanserli hücrelerin varlığı veya evresi hakkında bilgi verebilir. FT-IR spektroskopisi kullanılarak elde edilen veriler, istatistiksel analiz yöntemleriyle işlenir. Bu analizler, kanserli ve sağlıklı prostat dokuları arasındaki moleküler farkları belirlemek için kullanılır. Bu şekilde, prostat kanserinin teşhisinde FTIR spektroskopisi hassas ve doğru sonuçlar elde etmeye yardımcı olabilir.
Anahtar Kelime: FT-IR Spektroskopisi Prostat kanseri Teşhis yöntemleri Kemometrik Analiz

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA SAHIN Y (2024). Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. , 35 - 39. 10.46810/tdfd.1394182
Chicago SAHIN YILMAZ Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. (2024): 35 - 39. 10.46810/tdfd.1394182
MLA SAHIN YILMAZ Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. , 2024, ss.35 - 39. 10.46810/tdfd.1394182
AMA SAHIN Y Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. . 2024; 35 - 39. 10.46810/tdfd.1394182
Vancouver SAHIN Y Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. . 2024; 35 - 39. 10.46810/tdfd.1394182
IEEE SAHIN Y "Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer." , ss.35 - 39, 2024. 10.46810/tdfd.1394182
ISNAD SAHIN, YILMAZ. "Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer". (2024), 35-39. https://doi.org/10.46810/tdfd.1394182
APA SAHIN Y (2024). Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. Türk Doğa ve Fen Dergisi, 13(1), 35 - 39. 10.46810/tdfd.1394182
Chicago SAHIN YILMAZ Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. Türk Doğa ve Fen Dergisi 13, no.1 (2024): 35 - 39. 10.46810/tdfd.1394182
MLA SAHIN YILMAZ Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. Türk Doğa ve Fen Dergisi, vol.13, no.1, 2024, ss.35 - 39. 10.46810/tdfd.1394182
AMA SAHIN Y Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. Türk Doğa ve Fen Dergisi. 2024; 13(1): 35 - 39. 10.46810/tdfd.1394182
Vancouver SAHIN Y Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer. Türk Doğa ve Fen Dergisi. 2024; 13(1): 35 - 39. 10.46810/tdfd.1394182
IEEE SAHIN Y "Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer." Türk Doğa ve Fen Dergisi, 13, ss.35 - 39, 2024. 10.46810/tdfd.1394182
ISNAD SAHIN, YILMAZ. "Investigation of Fourier Transform Infrared (FT-IR) Spectroscopy and Chemometric Analysis Method as an Alternative Method in the Diagnosis of Prostate Cancer". Türk Doğa ve Fen Dergisi 13/1 (2024), 35-39. https://doi.org/10.46810/tdfd.1394182