Yıl: 2024 Cilt: 20 Sayı: 1 Sayfa Aralığı: 35 - 41 Metin Dili: İngilizce DOI: 10.4274/BMJ.galenos.2023.2022.11-1 İndeks Tarihi: 10-06-2024

Is Ischemic Stroke Declines During the COVID-19 Pandemic?

Öz:
Objective: A decrease in the number of ischemic strokes has been reported during the coronavirus disease-2019 (COVID-19) pandemic period. The aim of this study was to determine the effect of COVID-19 and associated risk factors on the number of ischemic strokes in hospitalizations during the COVID-19 period. Methods: This cross-sectional study was conducted using hospital records. Data of patients who underwent a COVID-19 real-time reverse- transcriptase polymerase chain reaction (RT-PCR) test between 2020 and 2021 were included. In addition to RT-PCR test results, the diagnosis of ischemic stroke and known risk factors for ischemic stroke (gender, age, diabetes mellitus, chronic obstructive pulmonary disease, hypertension, hypercholesterolemia, congestive heart failure, coronary artery disease, peripheral vascular disease, chronic kidney disease) were evaluated. Results: According to the inclusion criteria, 25,522 patient records were included in the analysis. There were 123 (0.6%) acute ischemic stroke patients among 19,051 COVID-19-negative patients and 23 (0.4%) among 6471 positive patients. Among the covariates, age and diabetes have a significant effect on acute ischemic stroke. In path analysis, the negative direct effect of RT-PCR positivity on acute ischemic stroke was reversed through the mediator variable effect of diabetes and age. Patients with diabetes and higher age have an increased risk of acute ischemic stroke if they have COVID-19. Conclusion: Evidence is not satisfactory to determine the effect of COVID-19 on ischemic stroke. Reports of a decrease in the number of hospitalizations due to ischemic stroke are accumulating. This result may be due to the direct effect of COVID-19, the lack of recognition of clinical symptoms, or the decrease in hospital admissions of patients without a severe clinical picture. In the presence of accompanying risk factors such as age and diabetes that will aggravate the stroke clinic, the reducing effect of COVID-19 on the number of ischemic strokes disappears.
Anahtar Kelime:

COVİD-19 Pandemisinde İskemik İnmeler Azaldı mı?

Öz:
Amaç: Yeni koronavirüs hastalığı-2019 (COVİD-19) pandemi döneminde iskemik inme sayısında azalma bildirilmiştir. Çalışmanın amacı, COVİD-19 döneminde hastaneye yatışlarda COVİD-19 ve ilişkili risk faktörlerinin iskemik inme sayısı üzerindeki etkisini belirlemektir. Gereç ve Yöntem: Bu kesitsel çalışma hastane kayıtları üzerinden yapıldı. 2020-2021 tarihlerinde COVİD-19 gerçek zamanlı ters transkriptaz- polimeraz zincir reaksiyonu (RT-PCR) testi yaptırmış hasta verileri dahil edildi. RT-PCR test sonuçlarına ek olarak, iskemik inme tanısı, iskemik inme için bilinen risk faktörleri (cinsiyet, yaş, diabetes mellitus, kronik obstrüktif akciğer hastalığı, hipertansiyon, hiperkolesterolemi, konjestif kalp yetmezliği, koroner arter hastalığı, periferik vasküler hastalık, kronik böbrek hastalığı) değerlendirildi. Bulgular: Dahil etme kriterlerine göre 25.522 hasta kaydı analize dahil edildi. 19.051 COVİD-19 negatif arasında 123 (%0,6), 6471 pozitif hasta arasında 23 (%0,4) akut iskemik inme hastası vardı. Ortak değişkenler arasında yaş ve diyabetin akut iskemik inme üzerinde önemli bir etkisi olduğu belirlendi. Path analizinde, RT-PCR pozitifliğinin akut iskemik inme üzerindeki olumsuz doğrudan etkisi, diyabet ve yaşın aracı değişken etkisi ile tersine çevrilmiştir, diyabetli ve daha ileri yaştaki hastalarda COVİD-19 varsa akut iskemik inme riski artmıştır. Sonuç: COVİD-19’un iskemik inme üzerindeki etkisine karar vermek için kanıtlar tatmin edici değildir. İskemik inme nedeniyle hastaneye yatış sayısında azalma raporları birikmektedir. Bu sonuç, COVİD-19’un doğrudan etkisi olabileceği gibi, klinik semptomların tanınmaması veya ciddi bir klinik tabloya sahip olmayan hastaların hastaneye başvurularının azalmasından da kaynaklanabilir. İnme kliniğini ağırlaştıracak yaş ve diyabet gibi eşlik eden risk faktörlerinin varlığında COVİD-19’un iskemik inme sayısını azaltıcı etkisi ortadan kalkar.
Anahtar Kelime:

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APA Ocak Ö, ŞAHİN E, TORAMAN Ç (2024). Is Ischemic Stroke Declines During the COVID-19 Pandemic?. , 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
Chicago Ocak Özgül,ŞAHİN Erkan Melih,TORAMAN Çetin Is Ischemic Stroke Declines During the COVID-19 Pandemic?. (2024): 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
MLA Ocak Özgül,ŞAHİN Erkan Melih,TORAMAN Çetin Is Ischemic Stroke Declines During the COVID-19 Pandemic?. , 2024, ss.35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
AMA Ocak Ö,ŞAHİN E,TORAMAN Ç Is Ischemic Stroke Declines During the COVID-19 Pandemic?. . 2024; 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
Vancouver Ocak Ö,ŞAHİN E,TORAMAN Ç Is Ischemic Stroke Declines During the COVID-19 Pandemic?. . 2024; 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
IEEE Ocak Ö,ŞAHİN E,TORAMAN Ç "Is Ischemic Stroke Declines During the COVID-19 Pandemic?." , ss.35 - 41, 2024. 10.4274/BMJ.galenos.2023.2022.11-1
ISNAD Ocak, Özgül vd. "Is Ischemic Stroke Declines During the COVID-19 Pandemic?". (2024), 35-41. https://doi.org/10.4274/BMJ.galenos.2023.2022.11-1
APA Ocak Ö, ŞAHİN E, TORAMAN Ç (2024). Is Ischemic Stroke Declines During the COVID-19 Pandemic?. Bakırköy Tıp Dergisi, 20(1), 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
Chicago Ocak Özgül,ŞAHİN Erkan Melih,TORAMAN Çetin Is Ischemic Stroke Declines During the COVID-19 Pandemic?. Bakırköy Tıp Dergisi 20, no.1 (2024): 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
MLA Ocak Özgül,ŞAHİN Erkan Melih,TORAMAN Çetin Is Ischemic Stroke Declines During the COVID-19 Pandemic?. Bakırköy Tıp Dergisi, vol.20, no.1, 2024, ss.35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
AMA Ocak Ö,ŞAHİN E,TORAMAN Ç Is Ischemic Stroke Declines During the COVID-19 Pandemic?. Bakırköy Tıp Dergisi. 2024; 20(1): 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
Vancouver Ocak Ö,ŞAHİN E,TORAMAN Ç Is Ischemic Stroke Declines During the COVID-19 Pandemic?. Bakırköy Tıp Dergisi. 2024; 20(1): 35 - 41. 10.4274/BMJ.galenos.2023.2022.11-1
IEEE Ocak Ö,ŞAHİN E,TORAMAN Ç "Is Ischemic Stroke Declines During the COVID-19 Pandemic?." Bakırköy Tıp Dergisi, 20, ss.35 - 41, 2024. 10.4274/BMJ.galenos.2023.2022.11-1
ISNAD Ocak, Özgül vd. "Is Ischemic Stroke Declines During the COVID-19 Pandemic?". Bakırköy Tıp Dergisi 20/1 (2024), 35-41. https://doi.org/10.4274/BMJ.galenos.2023.2022.11-1