Yıl: 2024 Cilt: 52 Sayı: 2 Sayfa Aralığı: 60 - 67 Metin Dili: İngilizce DOI: 10.4274/TJAR.2024.231485 İndeks Tarihi: 11-06-2024

Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial

Öz:
Objective: Different anaesthetists for sedation or monitored anaesthesia care have been used for colonoscopy. The target of this research was the ability to perform colonoscopy under a painless degree of sedation and the prevalence of undesired proceedings. Methods: A total of 60 patients were randomly divided into two groups: Group D received dexmedetomidine and Group PF received propofol-fentanyl. Patients in both groups received the same infusion ratio. The minimum infusion amount of dexmetatomidine is (0.1 to 0.4 μg kg-1 h-1) in Group D, whereas fentanyl is administered at a rate of 0.01 to 0.05 μg kg-1 min-1 in the PF group during the approximately 45-min colonoscopy. Results: Group D exhibited significantly lower modified Observer’s Assessment of Alertness/Sedation (OAA/S) scores at intraoperative time points T1-T12. Group D also exhibited significantly lower visual analog scale scores for pain at intraoperative time points T4 and T7. The mean arterial pressure was significantly lower in Group D at intraoperative times T6-T8 and T11-T12, as well as upon admission to the post-anaesthesia care unit (PACU) and 30 min after admission to the PACU. The results of the ANOVA tests revealed a significantly lower heart rate in Group D. The respiratory rate exhibited a notable decrease during time intervals T8 and T10 in the PF group. Conclusion: The administration of dexmetatomidine and propofol-fentanyl during colonoscopy was found to be safe. In addition, dexmetatomidine may present significant benefits in this context because of its lower occurrence of adverse respiratory events.
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APA seyam s, aboelsuod M, Ahmed I, Elabd hassan A (2024). Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. , 60 - 67. 10.4274/TJAR.2024.231485
Chicago seyam sameh,aboelsuod Mohamed Abelgawad Abdelhalim,Ahmed Ismail,Elabd hassan Abdallah Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. (2024): 60 - 67. 10.4274/TJAR.2024.231485
MLA seyam sameh,aboelsuod Mohamed Abelgawad Abdelhalim,Ahmed Ismail,Elabd hassan Abdallah Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. , 2024, ss.60 - 67. 10.4274/TJAR.2024.231485
AMA seyam s,aboelsuod M,Ahmed I,Elabd hassan A Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. . 2024; 60 - 67. 10.4274/TJAR.2024.231485
Vancouver seyam s,aboelsuod M,Ahmed I,Elabd hassan A Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. . 2024; 60 - 67. 10.4274/TJAR.2024.231485
IEEE seyam s,aboelsuod M,Ahmed I,Elabd hassan A "Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial." , ss.60 - 67, 2024. 10.4274/TJAR.2024.231485
ISNAD seyam, sameh vd. "Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial". (2024), 60-67. https://doi.org/10.4274/TJAR.2024.231485
APA seyam s, aboelsuod M, Ahmed I, Elabd hassan A (2024). Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. Turkish Journal of Anaesthesiology and Reanimation, 52(2), 60 - 67. 10.4274/TJAR.2024.231485
Chicago seyam sameh,aboelsuod Mohamed Abelgawad Abdelhalim,Ahmed Ismail,Elabd hassan Abdallah Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. Turkish Journal of Anaesthesiology and Reanimation 52, no.2 (2024): 60 - 67. 10.4274/TJAR.2024.231485
MLA seyam sameh,aboelsuod Mohamed Abelgawad Abdelhalim,Ahmed Ismail,Elabd hassan Abdallah Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. Turkish Journal of Anaesthesiology and Reanimation, vol.52, no.2, 2024, ss.60 - 67. 10.4274/TJAR.2024.231485
AMA seyam s,aboelsuod M,Ahmed I,Elabd hassan A Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. Turkish Journal of Anaesthesiology and Reanimation. 2024; 52(2): 60 - 67. 10.4274/TJAR.2024.231485
Vancouver seyam s,aboelsuod M,Ahmed I,Elabd hassan A Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial. Turkish Journal of Anaesthesiology and Reanimation. 2024; 52(2): 60 - 67. 10.4274/TJAR.2024.231485
IEEE seyam s,aboelsuod M,Ahmed I,Elabd hassan A "Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial." Turkish Journal of Anaesthesiology and Reanimation, 52, ss.60 - 67, 2024. 10.4274/TJAR.2024.231485
ISNAD seyam, sameh vd. "Sedation for Colonoscopy Procedures Using Dexmedetomidine Versus Propofol-Fentanyl Infusions: A Prospective Randomized Controlled Trial". Turkish Journal of Anaesthesiology and Reanimation 52/2 (2024), 60-67. https://doi.org/10.4274/TJAR.2024.231485