Yıl: 2024 Cilt: 16 Sayı: 1 Sayfa Aralığı: 7 - 14 Metin Dili: İngilizce DOI: 10.4274/raed.galenos.2023.44153 İndeks Tarihi: 11-06-2024

The evaluation of dynamic and static balance in Familial Mediterranean fever patients

Öz:
Objective: Familial Mediterranean fever (FMF) presents with arthritis attacks, enthesitis, and synovitis in the lower extremities which suggests that balance disorders may develop. The purpose of this study is to evaluate the dynamic and static balance in FMF patients. Methods: This study was a prospective case-control study. The study included FMF patients who met the modified Tel Hashomer criteria as well as healthy participants. FMF patients’ demographics, clinical features, International Severity Scoring System and Maastricht Ankylosing Spondylitis Enthesitis score were assessed. The Berg Balance scale (BBS), Functional Reach test (FRT), timed up and go (TUG), and single leg stance (SLS) tests were used to assess balance performance. Results: The patient group consisted of 94 FMF patients (62.8% females), and the control group consisted of 90 healthy individuals (52.7% females). When the FRT, BBS, TUG, and SLS scores of the patient and control groups were compared, the patient group performed statistically worse in all scores. High risk of fall was found to be associated with longer disease duration and older age (p<0.001 and p<0.001). Visual analog scale scores during the attack were higher in patients at risk of falling, and arthralgia and amyloidosis were also more common. (p=0.032, p=0.002, and p=0.001, respectively). Conclusion: The study found that compared to healthy individuals, FMF patients exhibited worse dynamic and static balance. The existence of amyloidosis and enthesitis, together with a longer and more severe illness, could all be factors in balance loss.
Anahtar Kelime: Dynamic balance Familial Mediterranean fever static balance

Ailevi Akdeniz ateşi hastalarında statik ve dinamik denge bozukluklarının değerlendirilmesi

Öz:
Amaç: Ailevi Akdeniz ateşinin (AAA) yaşam boyu süren enflamasyonun yanı sıra alt ekstremitelerde artrit, sinovit ve entezit atakları ile seyretmesi hastalarda denge bozukluğu gelişebileceğini düşündürmektedir. Bu çalışmanın amacı AAA hastalarında statik ve dinamik denge bozukluğunu değerlendirmektir. Yöntem: Çalışma prospektif olarak dizayn edilen bir çalışmadır. Modifiye Tel Hashomer kriterlerini karşılayan AAA hastaları ve sağlıklı gönüllüler çalışmaya dahil edildi. AAA hastalarının demografik verileri, klinik özellikleri, Maastricht Ankilozan Spondilit Entezit Skoru ve Uluslararası Şiddet Skorlama Sistemi değerlendirildi. Denge performansı Berg Denge ölçeği (BBS), fonksiyonel uzanma testi (FRT), zamanlı kalk ve yürü (TUG) ve tek ayak duruşu (SLS) testleri ile değerlendirildi. Bulgular: Hasta grubuna 94 AAA hastası (%62,8 kadın), kontrol grubuna ise 90 sağlıklı birey (%52,7 kadın) dahil edildi. Hasta ve kontrol grupları BBS, FRT, TUG ve SLS testleri açısından karşılaştırıldığında hasta grubundaki puanların tüm değerlendirmelerde istatistiksel olarak daha kötü olduğu görüldü. Düşme riski taşıyan AAA hastaları ileri yaşta ve hastalık süresi daha uzundu (sırasıyla p<0,001 ve p<0,001). Düşme riski olan hastalarda atak sırasındaki görsel analog ölçeği skorları, artralji varlığı ve amiloidoz varlığı daha yüksekti (sırasıyla p=0,032, p=0,002, p<0,001). Sonuç: Sonuç olarak AAA hastalarında dinamik ve statik dengenin sağlıklı bireylere göre daha kötü olduğu saptandı. Hastalığın daha uzun süreli ve daha şiddetli olması, entezit ve amiloidozun varlığı dengenin bozulmasına katkıda bulunabilmektedir.
Anahtar Kelime: Dinamik denge Ailevi Akdeniz ateşi statik denge

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
0
0
0
  • 1. Ben-Chetrit E, Levy M. Familial Mediterranean fever. Lancet 1998;351:659-64.
  • 2. Brik R, Shinawi M, Kasinetz L, Gershoni-Baruch R. The musculoskeletal manifestations of familial Mediterranean fever in children genetically diagnosed with the disease. Arthritis Rheum 2001;44:1416-9.
  • 3. Sohar E, Gafni J, Pras M, Heller H. Familial Mediterranean fever. A survey of 470 cases and review of the literature. Am J Med 1967;43:227-53.
  • 4. Livneh A, Langevitz P, Zemer D, et al. The changing face of familial Mediterranean fever. Semin Arthritis Rheum 1996;26:612-27.
  • 5. Zung A, Barash G, Zadik Z, Barash J. Familial Mediterranean fever and growth: effect of disease severity and colchicine treatment. J Pediatr Endocrinol Metab 2006;19:155-60.
  • 6. van der Hilst JC, Simon A, Drenth JP. Hereditary periodic fever and reactive amyloidosis. Clin Exp Med 2005;5:87-98.
  • 7. Zemer D, Livneh A, Danon YL, Pras M, Sohar E. Long-term colchicine treatment in children with familial Mediterranean fever. Arthritis Rheum 1991;34:973-7.
  • 8. Celkan T, Celik M, Kasapçopur O, et al. The anemia of familial Mediterranean fever disease. Pediatr Hematol Oncol 2005;22:657-65.
  • 9. Duzova A, Ozaltin F, Ozon A, et al. Bone mineral density in children with familial Mediterranean fever. Clin Rheumatol 2004;23:230-4.
  • 10. Pompeu JE, Romano RSL, Pompeu SMAA, Lima SMAL. Static and dynamic balance in subjects with ankylosing spondylitis: literature review. Rev Bras Reumatol 2012;52:413-6.
  • 11. de Castro LA, Ribeiro LR, Mesquita R, et al. Static and functional balance in individuals with COPD: comparison with healthy controls and differences according to sex and disease severity. Respir Care 2016;61:1488-96.
  • 12. Aydoğ E, Bal A, Aydoğ ST, Çakci A. Evaluation of dynamic postural balance using the Biodex Stability System in rheumatoid arthritis patients. Clin Rheumatol 2006;25:462-7.
  • 13. Aydog E, Depedibi R, Bal A, Eksioglu E, Unlu E, Cakci A. Dynamic postural balance in ankylosing spondylitis patients. Rheumatology (Oxford) 2006;45:445-8.
  • 14. Duruoz MT, Baklacioglu HS, Sanal Toprak C, Gencer Atalay K, Atagunduz MP. The evaluation of the static and dynamic balance disorders in patients with psoriatic arthritis. Rheumatol Int 2018;38:2063-8.
  • 15. Yakut H, Özalevli S, Birlik AM. Postural balance and fall risk in patients with systemic sclerosis: A cross-sectional study. Arch Rheumatol 2021;36:167.
  • 16. Yılmaz R, İnanır A, Kazancı NÖ, Çakan N, Ali G. Evaluation of Dynamic Postural Balance in Pediatric Familial Mediterranean Fever Patients. J Pediatr Res 2018;5:134.
  • 17. Tarakcı E, Kısa EP, Arman N, Albayrak A. Physical activity and exercise in patients with pediatric rheumatic disease: A systematic search and review. Turk Arch Pediat 2021;56:179-86.
  • 18. Livneh A, Langevitz P, Zemer D, et al. Criteria for the diagnosis of familial Mediterranean fever. Arthritis Rheum 1997;40:1879-85.
  • 19. Kristensen S, Christensen JH, Schmidt EB, et al. Assessment of enthesitis in patients with psoriatic arthritis using clinical examination and ultrasound. Muscles Ligaments Tendons J 2016;6:241.
  • 20. Heuft-Dorenbosch L, Spoorenberg A, Van Tubergen A, et al. Assessment of enthesitis in ankylosing spondylitis. Ann Rheum Dis 2003;62:127-32.
  • 21. Demirkaya E, Acikel C, Hashkes P, et al. Development and initial validation of international severity scoring system for familial Mediterranean fever (ISSF). Ann Rheum Dis 2016;75:1051-6.
  • 22. Berg KO, Wood-Dauphinee SL, Williams JI, Maki B. Measuring balance in the elderly: validation of an instrument. Can J Public Health 1992;83(Suppl 2):S7-11.
  • 23. Shumway-Cook A, Baldwin M, Polissar NL, Gruber W. Predicting the probability for falls in community-dwelling older adults. Phys Ther 1997;77:812-9.
  • 24. Barry E, Galvin R, Keogh C, Horgan F, Fahey T. Is the Timed Up and Go test a useful predictor of risk of falls in community dwelling older adults: a systematic review and meta-analysis. BMC Geriatr 2014;14:14.
  • 25. Duncan PW, Weiner DK, Chandler J, Studenski S. Functional reach: a new clinical measure of balance. J Geratol 1990;45:M192-7.
  • 26. Thomas JI, Lane JV. A pilot study to explore the predictive validity of 4 measures of falls risk in frail elderly patients. Arch Phys Med Rehabil 2005;86:1636-40.
  • 27. Lin MR, Hwang HF, Hu MH, Wu HD, Wang YW, Huang FC. Psychometric comparisons of the timed up and go, one-leg stand, functional reach, and Tinetti balance measures in community- dwelling older people. J Am Geriatr Soc 2004;52:1343-8.
  • 28. Vellas BJ, Wayne SJ, Romero L, Baumgartner RN, Rubenstein LZ, Garry PJ. One-leg balance is an important predictor of injurious falls in older persons. J Am Geriatr Soc 1997;45:735-8.
  • 29. Isles RC, Choy NL, Steer M, Nitz JC. Normal values of balance tests in women aged 20-80. J Am Geriatr Soc 2004;52:1367-72.
  • 30. Bennie S, Bruner K, Dizon A, Fritz H, Goodman B, Peterson S. Measurements of balance: comparison of the Timed” Up and Go” test and Functional Reach test with the Berg Balance Scale. J Phys Ther Sci 2003;15:93-7.
  • 31. Lachmann HJ, Sengül B, Yavuzşen TU, et al. Clinical and subclinical inflammation in patients with familial Mediterranean fever and in heterozygous carriers of MEFV mutations. Rheumatology (Oxford, England) 2006;45:746-50.
  • 32. Ben-Zvi I, Livneh A. Chronic inflammation in FMF: markers, risk factors, outcomes and therapy. Nat Rev Rheumatol 2011;7:105-12.
  • 33. Salah S, El-Masry SA, Sheba HF, El-Banna RA, Saad W. Bone mineral density in Egyptian children with familial Mediterranean fever. Iran J Med Sci 2016;41:2.
  • 34. Yildirim K, Karatay S, Cetinkaya R, et al. Bone mineral density in patients with familial Mediterranean fever. Rheumatol Int 2010;30:305-8.
  • 35. Burnham JM. Inflammatory diseases and bone health in children. Curr Opin Rheumato 2012;24:548-53.
  • 36. Berkdemir Siverekli N, Sahin O, Senel S, Hayta E, Kaptanoglu E, Elden H. Bone mineral density in familial Mediterranean fever. Rheumatol Int 2012;32:2453-7.
  • 37. Konak HE, Kibar S, Ergin ES. The effect of single-task and dual- task balance exercise programs on balance performance in adults with osteoporosis: a randomized controlled preliminary trial. Osteoporos Int 2016;27:3271-8.
  • 38. Duruoz MT, Unal C, Bingul DK, Ulutatar F. Fatigue in familial Mediterranean fever and its relations with other clinical parameters. Rheumatol Int 2018;38:75-81.
  • 39. Kucuksahin O, Omma A, Ozdemirel AE, et al. Incidence of sleep disturbances in patients with familial Mediterranean fever and the relation of sleep quality with disease activity. Int J Rheum Dis 2018;21:1849-56.
  • 40. Makay B, Kiliçaslan SK, Anik A, et al. Assessment of sleep problems in children with familial Mediterranean fever. Int J Rheum Dis 2017;20:2106-12.
  • 41. Tunca M, Kirkali G, Soytürk M, Akar S, Pepys MB, Hawkins PN. Acute phase response and evolution of familial Mediter ranean fever. Lancet 1999;353:1415.
  • 42. Berkun Y, Padeh S, Reichman B, et al. A single testing of serum amyloid a levels as a tool for diagnosis and treatment dilemmas in familial Mediterranean fever. Semin Arthritis Rheum 2007;37:182-8.
  • 43. Siligato R, Gembillo G, Calabrese V, Conti G, Santoro D. Amyloidosis and Glomerular Diseases in Familial Mediterranean Fever. Medicina (Kaunas) 2021;57:1049.
  • 44. Shin SC, Robinson-Papp J. Amyloid neuropathies. Mt Sinai J Med 2012;79:733-48.
  • 45. Sherif AM, Refaie AF, Sheashaa HA, El-Tantawy AE, Sobh MA. Long-term evaluation of neuromyopathy in live donor FMF amyloidotic kidney transplant recipients. Am J Nephrol 2004;24:582-6.
  • 46. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. The International FMF Consortium. Cell 1997;90:797-807.
  • 47. Chae JJ, Wood G, Masters SL, et al. The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. Proc Natl Acad Sci U S A 2006;103:9982-7.
  • 48. Eshed I, Rosman Y, Livneh A, et al. Exertional leg pain in familial Mediterranean fever: a manifestation of an underlying enthesopathy and a marker of more severe disease. Arthritis Rheumatol 2014;66:3221-6.
  • 49. Tufan A, Mercan R, Tezcan ME, et al. Enthesopathy in patients with familial Mediterranean fever: increased prevalence in M694 V variant. Rheumatol Int 2013;33:1933-7.
  • 50. Sen N, Yilmaz M, Mercan R, et al. Enthesitis may be one of the signs of severe disease in familial Mediterranean fever. Clin Rheumatol 2021;40:1479-85.
APA Konak H, Güven S, Orhan K, atalar e, kucuksahin o, Erten Ş (2024). The evaluation of dynamic and static balance in Familial Mediterranean fever patients. , 7 - 14. 10.4274/raed.galenos.2023.44153
Chicago Konak Hatice Ecem,Güven Serdar Can,Orhan Kevser,atalar ebru,kucuksahin orhan,Erten Şükran The evaluation of dynamic and static balance in Familial Mediterranean fever patients. (2024): 7 - 14. 10.4274/raed.galenos.2023.44153
MLA Konak Hatice Ecem,Güven Serdar Can,Orhan Kevser,atalar ebru,kucuksahin orhan,Erten Şükran The evaluation of dynamic and static balance in Familial Mediterranean fever patients. , 2024, ss.7 - 14. 10.4274/raed.galenos.2023.44153
AMA Konak H,Güven S,Orhan K,atalar e,kucuksahin o,Erten Ş The evaluation of dynamic and static balance in Familial Mediterranean fever patients. . 2024; 7 - 14. 10.4274/raed.galenos.2023.44153
Vancouver Konak H,Güven S,Orhan K,atalar e,kucuksahin o,Erten Ş The evaluation of dynamic and static balance in Familial Mediterranean fever patients. . 2024; 7 - 14. 10.4274/raed.galenos.2023.44153
IEEE Konak H,Güven S,Orhan K,atalar e,kucuksahin o,Erten Ş "The evaluation of dynamic and static balance in Familial Mediterranean fever patients." , ss.7 - 14, 2024. 10.4274/raed.galenos.2023.44153
ISNAD Konak, Hatice Ecem vd. "The evaluation of dynamic and static balance in Familial Mediterranean fever patients". (2024), 7-14. https://doi.org/10.4274/raed.galenos.2023.44153
APA Konak H, Güven S, Orhan K, atalar e, kucuksahin o, Erten Ş (2024). The evaluation of dynamic and static balance in Familial Mediterranean fever patients. Ulusal Romatoloji Dergisi, 16(1), 7 - 14. 10.4274/raed.galenos.2023.44153
Chicago Konak Hatice Ecem,Güven Serdar Can,Orhan Kevser,atalar ebru,kucuksahin orhan,Erten Şükran The evaluation of dynamic and static balance in Familial Mediterranean fever patients. Ulusal Romatoloji Dergisi 16, no.1 (2024): 7 - 14. 10.4274/raed.galenos.2023.44153
MLA Konak Hatice Ecem,Güven Serdar Can,Orhan Kevser,atalar ebru,kucuksahin orhan,Erten Şükran The evaluation of dynamic and static balance in Familial Mediterranean fever patients. Ulusal Romatoloji Dergisi, vol.16, no.1, 2024, ss.7 - 14. 10.4274/raed.galenos.2023.44153
AMA Konak H,Güven S,Orhan K,atalar e,kucuksahin o,Erten Ş The evaluation of dynamic and static balance in Familial Mediterranean fever patients. Ulusal Romatoloji Dergisi. 2024; 16(1): 7 - 14. 10.4274/raed.galenos.2023.44153
Vancouver Konak H,Güven S,Orhan K,atalar e,kucuksahin o,Erten Ş The evaluation of dynamic and static balance in Familial Mediterranean fever patients. Ulusal Romatoloji Dergisi. 2024; 16(1): 7 - 14. 10.4274/raed.galenos.2023.44153
IEEE Konak H,Güven S,Orhan K,atalar e,kucuksahin o,Erten Ş "The evaluation of dynamic and static balance in Familial Mediterranean fever patients." Ulusal Romatoloji Dergisi, 16, ss.7 - 14, 2024. 10.4274/raed.galenos.2023.44153
ISNAD Konak, Hatice Ecem vd. "The evaluation of dynamic and static balance in Familial Mediterranean fever patients". Ulusal Romatoloji Dergisi 16/1 (2024), 7-14. https://doi.org/10.4274/raed.galenos.2023.44153