Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma

Yaşar, Şirin; SERDAR, Zehra Aşiran; DORUK, Tuğba; Döner Aktaş, Nurhan; Gönenç, Işık

Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma

Zehra Aşiran SERDAR, (Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Dermatoloji Kliniği, İstanbul, Türkiye)

Işık GÖNENÇ, (Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Aile Hekimliği Kliniği, İstanbul, Türkiye)

Şirin YAŞAR, (Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Dermatoloji Kliniği, İstanbul, Türkiye)

Tuğba DORUK, (Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Dermatoloji Kliniği, İstanbul, Türkiye)

Nurhan DÖNER (Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Dermatoloji Kliniği, İstanbul, Türkiye)

Marmara Medical Journal

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Yıl: 2011 Cilt: 24 Sayı: 3 Sayfa Aralığı: 200 - 202 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma

Öz:

El-ayak sendromu (EAS) bazı kemoterapötiklerin yan etkisi olarak dizestezi, keskin kenarlı plaklarla ve palmoplantar alanlarda simetrik lezyonlar şeklinde görünür. Olgumuz ileri evre metastatik karsinom için kapesitabin tedavisinin üçüncü döngüsünde avuç içi ve ayak tabanlarında hafif eritem ve deskuamasyon gelişen, 68 yaşındaki erkek hastadır. Bu olgu sunumu ile kapesitabin kemoterapisi alan hastalarda gelişebilen EAS konusuna dikkat çekmeyi ve bilinç düzeyini yükseltmeyi amaçladık. Günümüz literatüründe ağız mukozasında hemorajik bül oluşumu hakkında bilgiye rastlanmaması nedeniyle olgumuz dikkat çekicidir.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Metastatik kolon karsinomu tedavisinde kapesitabin'e bağlı ağır oral lezyonların eşlik ettiği el-ayak sendromu

Öz:

Hand-foot syndrome (HFS) is a side effect of some chemotherapeutics appearing as dysesthesia, sharp-edged plaques and symmetrical lesions on palmoplantar areas. Our case is a 68-year-old male patient who developed a slight erythema and desquamation on the palms and soles of the feet during the third cycle of capecitabine treatment for advanced metastatic carcinoma. With this case report we aimed to draw attention to the development of HFS in patients receiving chemotherapy with capecitabine and raise awareness in the issue. The nonexistance of data in contemporary literature about the occurrence of hemorrhagic bullae in the oral mucosa makes our case noteworthy.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

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APA	SERDAR Z, Gönenç I, Yaşar Ş, DORUK T, Döner Aktaş N (2011). Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. , 200 - 202.
Chicago	SERDAR Zehra Aşiran,Gönenç Işık,Yaşar Şirin,DORUK Tuğba,Döner Aktaş Nurhan Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. (2011): 200 - 202.
MLA	SERDAR Zehra Aşiran,Gönenç Işık,Yaşar Şirin,DORUK Tuğba,Döner Aktaş Nurhan Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. , 2011, ss.200 - 202.
AMA	SERDAR Z,Gönenç I,Yaşar Ş,DORUK T,Döner Aktaş N Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. . 2011; 200 - 202.
Vancouver	SERDAR Z,Gönenç I,Yaşar Ş,DORUK T,Döner Aktaş N Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. . 2011; 200 - 202.
IEEE	SERDAR Z,Gönenç I,Yaşar Ş,DORUK T,Döner Aktaş N "Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma." , ss.200 - 202, 2011.
ISNAD	SERDAR, Zehra Aşiran vd. "Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma". (2011), 200-202.

APA	SERDAR Z, Gönenç I, Yaşar Ş, DORUK T, Döner Aktaş N (2011). Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. Marmara Medical Journal, 24(3), 200 - 202.
Chicago	SERDAR Zehra Aşiran,Gönenç Işık,Yaşar Şirin,DORUK Tuğba,Döner Aktaş Nurhan Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. Marmara Medical Journal 24, no.3 (2011): 200 - 202.
MLA	SERDAR Zehra Aşiran,Gönenç Işık,Yaşar Şirin,DORUK Tuğba,Döner Aktaş Nurhan Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. Marmara Medical Journal, vol.24, no.3, 2011, ss.200 - 202.
AMA	SERDAR Z,Gönenç I,Yaşar Ş,DORUK T,Döner Aktaş N Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. Marmara Medical Journal. 2011; 24(3): 200 - 202.
Vancouver	SERDAR Z,Gönenç I,Yaşar Ş,DORUK T,Döner Aktaş N Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma. Marmara Medical Journal. 2011; 24(3): 200 - 202.
IEEE	SERDAR Z,Gönenç I,Yaşar Ş,DORUK T,Döner Aktaş N "Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma." Marmara Medical Journal, 24, ss.200 - 202, 2011.
ISNAD	SERDAR, Zehra Aşiran vd. "Hand-foot syndrome accompanied by severe oral lesions during capecitabine therapy for metastatic colon carcinoma". Marmara Medical Journal 24/3 (2011), 200-202.