Profound change has affected health organizations as well as all organizational structures. Organizational structures of health institutions influenced by considerable environmental effect are forced to have flexible features. Health institutions are transformed from clumsy structures to much more uncomplicated lean and marked-oriented ones in complying with the efforts of change. In this organizational transformation process, health institutions are engaging to significant changing efforts such as using better technology, process betterment and being uncomplicated ones. These changes affect the whole organizational structure and face profound resistances from time to time. So, it does become significant to take change decision, application policies and to conjecture how changes might affect workers. Health professionals who carry out these changes are supposed to take into account these important subjects and it is also significant that in order to be successful in change, health professionals should take into consideration change perceptions of health professionals and their expectations. This study aims to research how health professionals perceive change management process and their attitudes toward change. The findings suggest that resistance perception of health professionals against organizational change is at average level. The research also shows that risk perception of health professionals toward organizational change is average and their emotional reaction perception level is high and perception level toward support of change is low for nurses and high for medical doctors.