TY - JOUR TI - Effects of methidathion on Antioxidant enzyme activities and malondialdehyde level in midgut tissues of Lymantria dispar (Lepidoptera) larvae AB - Lymantria dispar larvae are very hazardous to forests and they also cause allergic reactions in humans. In the present study, distinct concentrations of methidathion were applied to L. dispar larvae via oak leaves which were prepared by the dipping method. The data obtained was statistically appraised using probit analysis and a $LC _{50/48h}$ value for L. dispar larvae found to be 25,480 ppm. Antioxidant defense components protect insects by scavenging reactive oxygen species, leading to oxidative stress. The present study was investigated the effects of $LC _{50/48h}$ value of methidathion, on the oxidative stress indicator, malondialdehyde (MDA), and antioxidant enzymes [superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)] activities in midgut tissues. There were statistically significant increases in the MDA level and SOD, CAT, GPx activities in the $LC _{50/48h}$ concentration of methidathion-treated larvae compared to the control larvae. These results indicated that methidathion which is an organophosphate pesticide, causes an increase in oxidative stress and we infered that increased oxidative stress induces antioxidant defence mechanisms. AU - Kalender, Yusuf AU - Kalender, Suna AU - UZUNHİSARCIKLI, Meltem AU - ASLANTÜRK, AYŞE PY - 2011 JO - Journal of the Entomological Research Society VL - 13 IS - 3 SN - 1302-0250 SP - 27 EP - 38 DB - TRDizin UR - http://search/yayin/detay/127024 ER -