İlaçlara bağlı Stevens-Johnson Sendromu

ALBAYRAK, Hülya; GÜRLEVİK, Zehra; ÖNDER, Elif; AYDIN, Yusuf

İlaçlara bağlı Stevens-Johnson Sendromu

Elif ÖNDER, (Düzce Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Düzce, Türkiye)

Hülya ALBAYRAK, (Düzce Üniversitesi, Tıp Fakültesi, Dermatoloji Anabilim Dalı, Düzce, Türkiye)

Zehra GÜRLEVİK, (Düzce Üniversitesi, Tıp Fakültesi, Dermatoloji Anabilim Dalı, Düzce, Türkiye)

Yusuf AYDIN (Düzce Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Düzce, Türkiye)

Düzce Tıp Fakültesi Dergisi

2 1

Yıl: 2010 Cilt: 12 Sayı: 1 Sayfa Aralığı: 98 - 103 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

İlaçlara bağlı Stevens-Johnson Sendromu

Öz:

Stevens Johnson Sendromu (SJS) sıklıkla ilaçlara bağlı olarak gelişen nadir fakat hayatı tehdit edebilen mukokutanöz bir cilt reaksiyonudur. Her yaşta ortaya çıkabilmekle birlikte en sık 2– 4. dekatlarda görülür. Mukokutanöz lezyonlar, sebep olan ilacın alınmasını takiben 1–14 günlük döneminin ardından ortaya çıkar. Gövde ve yüzde başlayan eritematöz makülopapüler döküntüler hızla tüm vücuda yayılır. Tedavisinde ilk basamak, sebep olan ilacın kesilmesi ve destek tedavisidir. Günümüzde altta yatan sitotoksik ve immünolojik mekanizmaların daha iyi anlaşılması yeni tedavi yaklaşımlarının ortaya çıkmasını ve mortalitenin azalmasını sağlamıştır. Bu yazıda ilaçlara bağlı olarak gelişen SJS hakkında kısa bir derleme sunulmaktadır.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Drugs induced Stevens-Johnson Syndrome

Öz:

Stevens Johnson Syndrome (SJS) is a life threatening mucocutaneous skin disease that mostly developed after using some drug. SJS mostly appear between 2-4th decades. Mucocutaneous lesions were seen between 1-14 days of drug intake. And these lesions spread diffusely all around the body. First treatment choice is the stopping of drug that cause SJS and giving supporting treatment. After understanding of underlying cytotoxic and immunological mechanism of SJS, new treatment approaches were developed and mortality of disease was reduced. We herein report a short review of drug induced SJS and its treatment.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	ÖNDER E, ALBAYRAK H, GÜRLEVİK Z, AYDIN Y (2010). İlaçlara bağlı Stevens-Johnson Sendromu. , 98 - 103.
Chicago	ÖNDER Elif,ALBAYRAK Hülya,GÜRLEVİK Zehra,AYDIN Yusuf İlaçlara bağlı Stevens-Johnson Sendromu. (2010): 98 - 103.
MLA	ÖNDER Elif,ALBAYRAK Hülya,GÜRLEVİK Zehra,AYDIN Yusuf İlaçlara bağlı Stevens-Johnson Sendromu. , 2010, ss.98 - 103.
AMA	ÖNDER E,ALBAYRAK H,GÜRLEVİK Z,AYDIN Y İlaçlara bağlı Stevens-Johnson Sendromu. . 2010; 98 - 103.
Vancouver	ÖNDER E,ALBAYRAK H,GÜRLEVİK Z,AYDIN Y İlaçlara bağlı Stevens-Johnson Sendromu. . 2010; 98 - 103.
IEEE	ÖNDER E,ALBAYRAK H,GÜRLEVİK Z,AYDIN Y "İlaçlara bağlı Stevens-Johnson Sendromu." , ss.98 - 103, 2010.
ISNAD	ÖNDER, Elif vd. "İlaçlara bağlı Stevens-Johnson Sendromu". (2010), 98-103.

APA	ÖNDER E, ALBAYRAK H, GÜRLEVİK Z, AYDIN Y (2010). İlaçlara bağlı Stevens-Johnson Sendromu. Düzce Tıp Fakültesi Dergisi, 12(1), 98 - 103.
Chicago	ÖNDER Elif,ALBAYRAK Hülya,GÜRLEVİK Zehra,AYDIN Yusuf İlaçlara bağlı Stevens-Johnson Sendromu. Düzce Tıp Fakültesi Dergisi 12, no.1 (2010): 98 - 103.
MLA	ÖNDER Elif,ALBAYRAK Hülya,GÜRLEVİK Zehra,AYDIN Yusuf İlaçlara bağlı Stevens-Johnson Sendromu. Düzce Tıp Fakültesi Dergisi, vol.12, no.1, 2010, ss.98 - 103.
AMA	ÖNDER E,ALBAYRAK H,GÜRLEVİK Z,AYDIN Y İlaçlara bağlı Stevens-Johnson Sendromu. Düzce Tıp Fakültesi Dergisi. 2010; 12(1): 98 - 103.
Vancouver	ÖNDER E,ALBAYRAK H,GÜRLEVİK Z,AYDIN Y İlaçlara bağlı Stevens-Johnson Sendromu. Düzce Tıp Fakültesi Dergisi. 2010; 12(1): 98 - 103.
IEEE	ÖNDER E,ALBAYRAK H,GÜRLEVİK Z,AYDIN Y "İlaçlara bağlı Stevens-Johnson Sendromu." Düzce Tıp Fakültesi Dergisi, 12, ss.98 - 103, 2010.
ISNAD	ÖNDER, Elif vd. "İlaçlara bağlı Stevens-Johnson Sendromu". Düzce Tıp Fakültesi Dergisi 12/1 (2010), 98-103.