Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis

DALKILINÇ, Doğan; DURGUT, Ramazan; GÜZEL, Murat

Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis

Ramazan DURGUT, (Mustafa Kemal Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Hatay, Türkiye)

Doğan DALKILINÇ, (Mustafa Kemal Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Hatay, Türkiye)

Murat GÜZEL (Ondokuz Mayıs Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Samsun, Türkiye)

Kafkas Üniversitesi Veteriner Fakültesi Dergisi

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Yıl: 2012 Cilt: 18 Sayı: 4 Sayfa Aralığı: 585 - 589 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis

Öz:

Bu çalışmanın amacı doğal enfekte visseral leishmaniasisli semptom gösteren köpeklerde lipit profilindeki değişiklikleri araştırmaktır. 10 sağlıklı ve 10 L. infantum ile enfekte toplam 20 sahipli köpek bu çalışmaya dahil edildi. Bütün köpeklerin anamnez bilgileri alındı ve fiziksel muayeneleri yapıldı. Enfekte köpeklerde visseral leishmaniasisin (VL) deri lezyonları, ağırlık kaybı, konjiktivitis, alopesi, kepeklenme, tırnaklarda uzama, lenfadenopati, güçsüzlük, iştahsızlık, epistaksis semptomlarından bir veya birkaçı tespit edildi. Canin visseral leishmaniasisin (CVL) teşhisi immunofluoresens antikor testi (IFAT) ve antikor titresinin 1:128’e eşit veya üzerinde belirlenmesi ile doğrulandı. Sağlıklı köpeklerin hiç birinde klinik semptom yoktu ve leishmania antikoru tespit edilmedi. Bu çalışmada semptomatik köpeklerde serum kolesterol, çok düşük dansiteli lipopretein (VLDL) ve düşük dansiteli lipopretein (LDL) seviyelerinin kontrol grubu verileriyle karşılaştırıldığında yüksek bulundu (P<0.01). Fakat trigliserit ve yüksek dansiteli lipopretein (HDL) seviyeleri kontrol hayvanlarından daha düşük belirlendi (P<0.01). Sonuçta CVL’in serum lipit profilinde önemli değişikliklere neden olduğu belirlendi.

Anahtar Kelime: kan kimyası lipoprotein hayvan patolojisi triyosilgliserol Leishmania donovani klinik görünüm yüksek yoğunluklu lipoprotein kan lipitleri düşük yoğunluklu lipoprotein köpek kolesterol viseral layşmanyaz

Konular: Veterinerlik

Semptomatik Leishmaniasisli köpeklerde serum lipit profilinin değerlendirilmesi

Öz:

The aim of this study was to investigate the serum lipid profile in naturally infected symptomatic dogs with visceral leishmaniasis (VL). A total of 20 owned dogs, comprising 10 healthy controls and 10 infected dogs with L. infantum were enrolled in this study. The clinical history and physical examination were performed in all dogs. Infected dogs showed one or more signs of canine leishmaniasis such as skin lesions, loss of weight, conjunctivitis, alopecia, scaling, onychogryphosis, lymphadenopathy, weakness, anorexia, and epistaxis. The diagnosis of canine visceral leishmaniasis (CVL) was confirmed by the immunofluorescence antibody test (IFAT) with an antibody titer over or equal to 1:128. None of the healthy dogs had clinical signs consistent with any of the disease and were all seronegative for leishmaniasis. In this study, serum cholesterol, very low density lipoprotein (VLDL) and low density lipoprotein (LDL) levels were significantly higher (P<0.01) in symptomatic dogs when compared to control animals. However, triglyceride and high density lipoprotein (HDL) levels were lower (P<0.01) than those of the controls. In conclusion, it was determined that CVL induce significant changes in serum lipid profile.

Anahtar Kelime: blood lipids low density lipoprotein dogs cholesterol visceral leishmaniasis blood chemistry lipoproteins animal pathology triacylglycerols Leishmania donovani clinical aspects high density lipoprotein

Konular: Veterinerlik

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	DURGUT R, DALKILINÇ D, GÜZEL M (2012). Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. , 585 - 589.
Chicago	DURGUT Ramazan,DALKILINÇ Doğan,GÜZEL Murat Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. (2012): 585 - 589.
MLA	DURGUT Ramazan,DALKILINÇ Doğan,GÜZEL Murat Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. , 2012, ss.585 - 589.
AMA	DURGUT R,DALKILINÇ D,GÜZEL M Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. . 2012; 585 - 589.
Vancouver	DURGUT R,DALKILINÇ D,GÜZEL M Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. . 2012; 585 - 589.
IEEE	DURGUT R,DALKILINÇ D,GÜZEL M "Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis." , ss.585 - 589, 2012.
ISNAD	DURGUT, Ramazan vd. "Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis". (2012), 585-589.

APA	DURGUT R, DALKILINÇ D, GÜZEL M (2012). Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 18(4), 585 - 589.
Chicago	DURGUT Ramazan,DALKILINÇ Doğan,GÜZEL Murat Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 18, no.4 (2012): 585 - 589.
MLA	DURGUT Ramazan,DALKILINÇ Doğan,GÜZEL Murat Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.18, no.4, 2012, ss.585 - 589.
AMA	DURGUT R,DALKILINÇ D,GÜZEL M Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2012; 18(4): 585 - 589.
Vancouver	DURGUT R,DALKILINÇ D,GÜZEL M Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2012; 18(4): 585 - 589.
IEEE	DURGUT R,DALKILINÇ D,GÜZEL M "Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 18, ss.585 - 589, 2012.
ISNAD	DURGUT, Ramazan vd. "Evaluation of the serum lipid profiles in dogs with symptomatic visceral leishmaniasis". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 18/4 (2012), 585-589.