Determination of lidocaine based on electrocatalysis of a chemically modified electrode

Tan, Gamze; BOLAT, GÜLÇİN; ONUR, MEHMET ALİ; ABACI, Serdar

Determination of lidocaine based on electrocatalysis of a chemically modified electrode

Gamze TAN, (Hacettepe Üniversitesi, Fen Bilimleri Enstitüsü, Biyoloji Bölümü, Ankara, Türkiye)

Gülçin BOLAT, (Hacettepe Üniversitesi, Fen Fakültesi, Kimya Bölümü, Ankara, Türkiye)

MEHMET ALİ ONUR, (Hacettepe Üniversitesi, Fen Fakültesi, Biyoloji Bölümü, Ankara, Türkiye)

Serdar ABACI (Hacettepe Üniversitesi, Fen Bilimleri Enstitüsü, Biyoloji Bölümü, Ankara, Türkiye)

Turkish Journal of Chemistry

3 0

Yıl: 2012 Cilt: 36 Sayı: 4 Sayfa Aralığı: 593 - 600 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Determination of lidocaine based on electrocatalysis of a chemically modified electrode

Öz:

The potential application of biochemically modified electrodes was investigated for construction of a drug biosensor. The electrocatalytic response of lidocaine was examined through modified electrodes using the electron transfer ability of hemoglobin (Hb) immobilized on gold film modified with a self-assembled monolayer (SAM) of 3-mercaptopropionic acid (MPA). According to the results of voltammetric studies, Au/MPA/Hb electrodes exhibited high sensitivity and good electrocatalytic activity for the reduction of lidocaine, motivating us to construct drug biosensors. With this study, a new electroanalytical procedure is proposed for the determination of lidocaine level in medical applications or therapeutic formulations containing lidocaine as the active ingredient.

Anahtar Kelime:

Konular: Mühendislik, Kimya

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Tan G, BOLAT G, ONUR M, ABACI S (2012). Determination of lidocaine based on electrocatalysis of a chemically modified electrode. , 593 - 600.
Chicago	Tan Gamze,BOLAT GÜLÇİN,ONUR MEHMET ALİ,ABACI Serdar Determination of lidocaine based on electrocatalysis of a chemically modified electrode. (2012): 593 - 600.
MLA	Tan Gamze,BOLAT GÜLÇİN,ONUR MEHMET ALİ,ABACI Serdar Determination of lidocaine based on electrocatalysis of a chemically modified electrode. , 2012, ss.593 - 600.
AMA	Tan G,BOLAT G,ONUR M,ABACI S Determination of lidocaine based on electrocatalysis of a chemically modified electrode. . 2012; 593 - 600.
Vancouver	Tan G,BOLAT G,ONUR M,ABACI S Determination of lidocaine based on electrocatalysis of a chemically modified electrode. . 2012; 593 - 600.
IEEE	Tan G,BOLAT G,ONUR M,ABACI S "Determination of lidocaine based on electrocatalysis of a chemically modified electrode." , ss.593 - 600, 2012.
ISNAD	Tan, Gamze vd. "Determination of lidocaine based on electrocatalysis of a chemically modified electrode". (2012), 593-600.

APA	Tan G, BOLAT G, ONUR M, ABACI S (2012). Determination of lidocaine based on electrocatalysis of a chemically modified electrode. Turkish Journal of Chemistry, 36(4), 593 - 600.
Chicago	Tan Gamze,BOLAT GÜLÇİN,ONUR MEHMET ALİ,ABACI Serdar Determination of lidocaine based on electrocatalysis of a chemically modified electrode. Turkish Journal of Chemistry 36, no.4 (2012): 593 - 600.
MLA	Tan Gamze,BOLAT GÜLÇİN,ONUR MEHMET ALİ,ABACI Serdar Determination of lidocaine based on electrocatalysis of a chemically modified electrode. Turkish Journal of Chemistry, vol.36, no.4, 2012, ss.593 - 600.
AMA	Tan G,BOLAT G,ONUR M,ABACI S Determination of lidocaine based on electrocatalysis of a chemically modified electrode. Turkish Journal of Chemistry. 2012; 36(4): 593 - 600.
Vancouver	Tan G,BOLAT G,ONUR M,ABACI S Determination of lidocaine based on electrocatalysis of a chemically modified electrode. Turkish Journal of Chemistry. 2012; 36(4): 593 - 600.
IEEE	Tan G,BOLAT G,ONUR M,ABACI S "Determination of lidocaine based on electrocatalysis of a chemically modified electrode." Turkish Journal of Chemistry, 36, ss.593 - 600, 2012.
ISNAD	Tan, Gamze vd. "Determination of lidocaine based on electrocatalysis of a chemically modified electrode". Turkish Journal of Chemistry 36/4 (2012), 593-600.