Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract

BIPLAB, Kaishar Parvej; RAHMAN, Masudur; SIDDIQUE, Saiful Alam; UDDIN, Helal; HOSSAIN, Aslam

Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract

Masudur RAHMAN, (Department of Pharmacy, International Islamic University Chittagong, Chittagong 4203, Bangladesh)

Aslam HOSSAIN, (Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh)

Saiful Alam SIDDIQUE, (Department of Pharmacy, International Islamic University Chittagong, Chittagong 4203, Bangladesh)

Kaishar Parvej BIPLAB, (Department of Pharmacy, International Islamic University Chittagong, Chittagong 4203, Bangladesh)

Helal UDDIN (Department of Pharmacy, International Islamic University Chittagong, Chittagong 4203, Bangladesh)

Turkish Journal of Biology

4 0

Yıl: 2012 Cilt: 36 Sayı: 5 Sayfa Aralığı: 574 - 579 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract

Öz:

Alocasia macrorrhizos (L.) (Araceae), a coarse and erect plant that is widely cultivated to be eaten as a vegetable throughout Bangladesh, has been reported to possess a number of medicinal properties. The antihyperglycemic, antioxidant, and cytotoxic effects of the methanol extract of A. macrorrhizos rhizomes were investigated. The extract was given at a single dose (250 and 500 mg/kg) in alloxan-induced hyperglycemic mice. The extract at 500 mg/kg produced a significant (P < 0.05) decrease in the blood glucose level (55.49%) at 8 h of treatment when compared with the control and was comparable with the reference drug, metformin. The extract was also subjected to antioxidant potentiality and brine shrimp lethality bioassays. The IC50 value of the extract was 693.0 μg/mL and the LC50 was 188.14 μg/mL.

Anahtar Kelime: Alocasia macrorrhiza antineoplastic agents hyperglycaemia antioxidants diabetes alloxan rhizomes root vegetables plant extracts

Konular: Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	RAHMAN M, HOSSAIN A, SIDDIQUE S, BIPLAB K, UDDIN H (2012). Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. , 574 - 579.
Chicago	RAHMAN Masudur,HOSSAIN Aslam,SIDDIQUE Saiful Alam,BIPLAB Kaishar Parvej,UDDIN Helal Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. (2012): 574 - 579.
MLA	RAHMAN Masudur,HOSSAIN Aslam,SIDDIQUE Saiful Alam,BIPLAB Kaishar Parvej,UDDIN Helal Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. , 2012, ss.574 - 579.
AMA	RAHMAN M,HOSSAIN A,SIDDIQUE S,BIPLAB K,UDDIN H Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. . 2012; 574 - 579.
Vancouver	RAHMAN M,HOSSAIN A,SIDDIQUE S,BIPLAB K,UDDIN H Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. . 2012; 574 - 579.
IEEE	RAHMAN M,HOSSAIN A,SIDDIQUE S,BIPLAB K,UDDIN H "Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract." , ss.574 - 579, 2012.
ISNAD	RAHMAN, Masudur vd. "Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract". (2012), 574-579.

APA	RAHMAN M, HOSSAIN A, SIDDIQUE S, BIPLAB K, UDDIN H (2012). Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. Turkish Journal of Biology, 36(5), 574 - 579.
Chicago	RAHMAN Masudur,HOSSAIN Aslam,SIDDIQUE Saiful Alam,BIPLAB Kaishar Parvej,UDDIN Helal Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. Turkish Journal of Biology 36, no.5 (2012): 574 - 579.
MLA	RAHMAN Masudur,HOSSAIN Aslam,SIDDIQUE Saiful Alam,BIPLAB Kaishar Parvej,UDDIN Helal Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. Turkish Journal of Biology, vol.36, no.5, 2012, ss.574 - 579.
AMA	RAHMAN M,HOSSAIN A,SIDDIQUE S,BIPLAB K,UDDIN H Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. Turkish Journal of Biology. 2012; 36(5): 574 - 579.
Vancouver	RAHMAN M,HOSSAIN A,SIDDIQUE S,BIPLAB K,UDDIN H Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract. Turkish Journal of Biology. 2012; 36(5): 574 - 579.
IEEE	RAHMAN M,HOSSAIN A,SIDDIQUE S,BIPLAB K,UDDIN H "Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract." Turkish Journal of Biology, 36, ss.574 - 579, 2012.
ISNAD	RAHMAN, Masudur vd. "Antihyperglycemic, antioxidant, and cytotoxic activities of Alocasia macrorrhizos (L.) rhizome extract". Turkish Journal of Biology 36/5 (2012), 574-579.