The musculoskeletal metastasis of the lung cancers is rare and locates usually at the spine, pelvis and femur. The cranial metastasis of lung cancer is very rare and generally in small size. Large bone destruction is not reported yet. Fifty six years old male patient was admitted to our hospital with the complaints of cough and respiratory difficulty. The needle biopsy of the lung revealed the diagnosis of squamous cell lung carcinoma (Grade 4) and the patient underwent palliative radiotherapy. The patient was admitted to our hospital 6 month later with rapidly growing mass lesion on the forehead. The radiological examination showed an extraaxial mass lesion 10x9x8 cm in size, which compressed on the brain tissue and caused large destruction in the frontal bone. The mass lesion was removed surgically, the brain tissue was decompressed and the bone defect was repaired with synthetic material. Although similar cases were reported previously, a lung carcinoma, which caused bone defect in this size, was not reported. For such metastases, removal of the mass lesion and cranioplasty are suggested.