Effects of lymphadenopathy on pulmonary function tests in sarcoidosis

GÖRGÜNER, Ali Metin; MERAL, Mehmet; YILMAZEL UÇAR, Elif; Aydin, Yener; Akgün, Metin; Aras, Omer; BİLEN, Yusuf; ALPER, Fatih

Effects of lymphadenopathy on pulmonary function tests in sarcoidosis

Ömer ARAZ, (Atatürk Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Erzurum, Türkiye)

Elif YILMAZEL UÇAR, (Atatürk Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Erzurum, Türkiye)

Yener AYDIN, (Atatürk Üniversitesi, Tıp Fakültesi, Göğüs Kalp Damar Cerrahisi Anabilim Dalı, Erzurum, Türkiye)

Mehmet MERAL, (Atatürk Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Erzurum, Türkiye)

Yusuf BİLEN, (Atatürk Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Erzurum, Türkiye)

Fatih ALPER, (Atatürk Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Erzurum, Türkiye)

Ali Metin GÖRGÜNER, (Atatürk Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Erzurum, Türkiye)

Metin AKGÜN (Atatürk Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Erzurum, Türkiye)

Türk Toraks Dergisi

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Yıl: 2013 Cilt: 14 Sayı: 4 Sayfa Aralığı: 152 - 157 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Effects of lymphadenopathy on pulmonary function tests in sarcoidosis

Öz:

AMAÇ: Sarkoidoz hastalarının takibinde Solunum Fonksiyon Testi (SFT) önemli bir parametredir. Biz, sarkoidozlu hastalarda parankim tutulumunu göz önünde bulundurarak lenfadenopati (LAP) varlığının solunum fonksiyon testi üzerine etkisini araştırmayı amaçladık. GEREÇ VE YÖNTEMLER: Çalışmamıza sarkoidoz tanısı konmuş, 63 hasta retrospektif olarak alındı. Hastalara SFT yapıldı. PA akciğer grafisi ve yüksek çözünürlüklü bilgisayarlı tomografi’leri (YÇBT) çekildi. Tüm hastaların bronkoskopik incelemeleri ve SFT’yi etkiley- en olası faktörler değerlendirildi. BULGULAR: Bronkoskopik bulgular ile SFT parametreleri arasında istatiksel olarak anlamlı ilişki vardı (p<0,01). Zorlu vital kapasitenin (FVC) ve 1. saniye zorlu ekspiratuvar volümün (FEV1) bronşlara komşuluğu olan LAP’dan daha çok etkilendiği tespit edildi. YÇBT’de parankim tutulumu derecesi göz önüne alındığında FVC ve FEV1’in hiler, intrahiler ve lober LAP varlığında istatiksel olarak daha fazla etkilendiği gözlendi (p=0,001). SONUÇ: Sarkoidoz hastalarında, hastalığın parankim tutulumu yanında, özel yerleşimli lenf nodu tutulumunun da SFT parame- treleri üzerinde önemli bir etkiye sahip olduğunu tespit ettik.

Anahtar Kelime:

Konular: Solunum Sistemi Kulak, Burun, Boğaz

Sarkoidoz’lu hastalarda lenfadenopatinin solunum fonksiyon testi üzerine etkisi

Öz:

OBJECTIVE: The pulmonary function test (PFT) is an important qu- antification test in the follow-up of sarcoidosis patients. We aimed to investigate the effect of lymphadenopathy (LAP) after controlling pulmonary parenchymal involvement on pulmonary function tests (PFTs) in the context of sarcoidosis. MATERIAL AND METHODS: A total of 63 sarcoidosis patients were enrolled retrospectively in the study. Respiratory functions were evaluated via PFTs. Radiological evaluations of the patients were made with chest x-ray and high-resolution computerized to- mography (HRCT). Bronchoscopic investigations were performed on all patients. Possible factors that affect PFTs were evaluated. RESULTS: There was a statistically significant correlation between the bronchoscopic findings and PFTs parameters (p<0.01). Forced vital capacity (FVC) was affected more in the presence of LAP in the adjacent bronchi and, it was similar the same for forced expiratory volume in the first second (FEV1). Considering the grade of HRCT findings, the presence of hilar LAP, intrahilar LAP and lobar LAP had a statistically significant effect on FVC and FEV1 (p=0.001). CONCLUSION: We revealed that in addition to parenchymal in- volvement of the disease, the special localization of lymph node involvement also has an important effect on the PFTs parameters of sarcoidosis patients.

Anahtar Kelime:

Konular: Solunum Sistemi Kulak, Burun, Boğaz

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Aras O, YILMAZEL UÇAR E, Aydin Y, MERAL M, BİLEN Y, ALPER F, GÖRGÜNER A, Akgün M (2013). Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. , 152 - 157.
Chicago	Aras Omer,YILMAZEL UÇAR Elif,Aydin Yener,MERAL Mehmet,BİLEN Yusuf,ALPER Fatih,GÖRGÜNER Ali Metin,Akgün Metin Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. (2013): 152 - 157.
MLA	Aras Omer,YILMAZEL UÇAR Elif,Aydin Yener,MERAL Mehmet,BİLEN Yusuf,ALPER Fatih,GÖRGÜNER Ali Metin,Akgün Metin Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. , 2013, ss.152 - 157.
AMA	Aras O,YILMAZEL UÇAR E,Aydin Y,MERAL M,BİLEN Y,ALPER F,GÖRGÜNER A,Akgün M Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. . 2013; 152 - 157.
Vancouver	Aras O,YILMAZEL UÇAR E,Aydin Y,MERAL M,BİLEN Y,ALPER F,GÖRGÜNER A,Akgün M Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. . 2013; 152 - 157.
IEEE	Aras O,YILMAZEL UÇAR E,Aydin Y,MERAL M,BİLEN Y,ALPER F,GÖRGÜNER A,Akgün M "Effects of lymphadenopathy on pulmonary function tests in sarcoidosis." , ss.152 - 157, 2013.
ISNAD	Aras, Omer vd. "Effects of lymphadenopathy on pulmonary function tests in sarcoidosis". (2013), 152-157.

APA	Aras O, YILMAZEL UÇAR E, Aydin Y, MERAL M, BİLEN Y, ALPER F, GÖRGÜNER A, Akgün M (2013). Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. Türk Toraks Dergisi, 14(4), 152 - 157.
Chicago	Aras Omer,YILMAZEL UÇAR Elif,Aydin Yener,MERAL Mehmet,BİLEN Yusuf,ALPER Fatih,GÖRGÜNER Ali Metin,Akgün Metin Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. Türk Toraks Dergisi 14, no.4 (2013): 152 - 157.
MLA	Aras Omer,YILMAZEL UÇAR Elif,Aydin Yener,MERAL Mehmet,BİLEN Yusuf,ALPER Fatih,GÖRGÜNER Ali Metin,Akgün Metin Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. Türk Toraks Dergisi, vol.14, no.4, 2013, ss.152 - 157.
AMA	Aras O,YILMAZEL UÇAR E,Aydin Y,MERAL M,BİLEN Y,ALPER F,GÖRGÜNER A,Akgün M Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. Türk Toraks Dergisi. 2013; 14(4): 152 - 157.
Vancouver	Aras O,YILMAZEL UÇAR E,Aydin Y,MERAL M,BİLEN Y,ALPER F,GÖRGÜNER A,Akgün M Effects of lymphadenopathy on pulmonary function tests in sarcoidosis. Türk Toraks Dergisi. 2013; 14(4): 152 - 157.
IEEE	Aras O,YILMAZEL UÇAR E,Aydin Y,MERAL M,BİLEN Y,ALPER F,GÖRGÜNER A,Akgün M "Effects of lymphadenopathy on pulmonary function tests in sarcoidosis." Türk Toraks Dergisi, 14, ss.152 - 157, 2013.
ISNAD	Aras, Omer vd. "Effects of lymphadenopathy on pulmonary function tests in sarcoidosis". Türk Toraks Dergisi 14/4 (2013), 152-157.