Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas

SHANG, Han-bing; ZHAO, Wei-guo; ZHANG, Wei-feng

Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas

Han-bing SHANG, (Rui Jin Hospital, Shanghai Jiao Tong University, Faculty of Medicine, Department of Neurosurgery, Shanghai, China)

Wei-guo ZHAO, (Rui Jin Hospital, Shanghai Jiao Tong University, Faculty of Medicine, Department of Neurosurgery, Shanghai, China)

Wei-feng ZHANG (Rui Jin Hospital, Shanghai Jiao Tong University, Faculty of Medicine, Department of Neurosurgery, Shanghai, China)

Turkish Neurosurgery

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Yıl: 2012 Cilt: 22 Sayı: 5 Sayfa Aralığı: 558 - 565 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas

Öz:

AMAÇ: Beyin gliomlu hastalarda preoperatif değerlendirme için manyetik rezonans spektroskopisi (MRS), kan oksijen seviyesine bağımlı görüntüleme (BOLD) ve difüzyon tensor görüntülemenin (DTI) önemini değerlendirmek. YÖNTEM ve GEREÇLER: Arka arkaya 23 gliom hastasında ameliyat öncesinde MRS, BOLD ve DTI yapıldı. Görüntülerin özellikleri histopatolojik sonuçlara göre değerlendirildi. BULGULAR: Gliomlarda kolin (Cho) /kreatin (Cr) oranı ve Cho tepe değerinde önemli artış varken N-asetilaspartat (NAA) tepe değerinde azalma görülür. Cho/Cr ve Cho/NAA oranı artışı ve bir lipid tepe değerinin varlığı yüksek dereceli malignansi ile tutarlıydı. Bir motor görev paradigması kullanılarak 20 hastada bir motor aktivasyon taraması yapıldı. Beş vakada motor aktivasyonlarda deformasyon ve displasman bulundu. Peritümöral beyaz madde kanalları ve tümör kenarı görünür difüzyon katsayısı (ADC) ve fraksiyonel anisotropi (FA) haritaları kullanılarak tanımlandı. Üç beyaz madde kanalı değişme paterni tanımlandı: displasman, infiltrasyon ve bozulma. Bu 23 hasta içinde 6 hastada tamamen tümör rezeksiyonu yapıldı, 8 hastada subtotal rezeksiyon yapıldı ve 9 hastada kısmi rezeksiyon yapıldı. Ameliyattan sonra hiçbir hastada ikincil nörolojik defisit görülmedi. SONUÇ: MRS, BOLD ve DTI tekniklerinin kombinasyonu beyin gliomlarında cerrahi öncesi uygun planlamayı mümkün kılar.

Anahtar Kelime:

Konular: Cerrahi

Beyin gliomlu hastalarda multimodal işlevsel manyetik rezonans görüntüleme teknikleri kullanılarak preoperatif değerlendirme

Öz:

AIM: To evaluate the value of magnetic resonance spectroscopy (MRS), blood oxygen level-dependent imaging (BOLD) and diffusion tensor imaging (DTI) for preoperative assessment in patients with brain gliomas. MaterIal and Methods: Twenty-three consecutive glioma patients underwent MRS, BOLD and DTI before operation. The characteristics of images were analysed according to histopathological results. Results: There is significant elevation of the choline (Cho) /creatine (Cr) ratio, Cho peak and depression of the N-acetylaspartate (NAA) peak in gliomas. Elevation of the Cho/Cr, Cho/NAA ratio and the presence of a lipids peak, were consistent with high-grade malignancy. A motor activation scan was achieved by using a motor task paradigm in 20 patients. Deformation and displacement of the motor activations was found in 5 cases. The margin of tumor and peritumoural white matter tracts were identified using apparent diffusion coefficient (ADC) and fractional anisotropy (FA) maps. Three patterns of white matter tracts alteration were identified: displacement, infiltration, and disruption. In all 23 patients, the tumors were completely resected in 6 patients, subtotal resected in 8 patients, partial resected in 9 patients. No secondary neurological deficit was occurred in all patients after operation. ConclusIon: The combination of MRS, BOLD, and DTI techniques allows appropriate presurgical planning of brain gliomas.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SHANG H, ZHAO W, ZHANG W (2012). Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. , 558 - 565.
Chicago	SHANG Han-bing,ZHAO Wei-guo,ZHANG Wei-feng Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. (2012): 558 - 565.
MLA	SHANG Han-bing,ZHAO Wei-guo,ZHANG Wei-feng Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. , 2012, ss.558 - 565.
AMA	SHANG H,ZHAO W,ZHANG W Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. . 2012; 558 - 565.
Vancouver	SHANG H,ZHAO W,ZHANG W Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. . 2012; 558 - 565.
IEEE	SHANG H,ZHAO W,ZHANG W "Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas." , ss.558 - 565, 2012.
ISNAD	SHANG, Han-bing vd. "Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas". (2012), 558-565.

APA	SHANG H, ZHAO W, ZHANG W (2012). Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. Turkish Neurosurgery, 22(5), 558 - 565.
Chicago	SHANG Han-bing,ZHAO Wei-guo,ZHANG Wei-feng Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. Turkish Neurosurgery 22, no.5 (2012): 558 - 565.
MLA	SHANG Han-bing,ZHAO Wei-guo,ZHANG Wei-feng Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. Turkish Neurosurgery, vol.22, no.5, 2012, ss.558 - 565.
AMA	SHANG H,ZHAO W,ZHANG W Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. Turkish Neurosurgery. 2012; 22(5): 558 - 565.
Vancouver	SHANG H,ZHAO W,ZHANG W Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. Turkish Neurosurgery. 2012; 22(5): 558 - 565.
IEEE	SHANG H,ZHAO W,ZHANG W "Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas." Turkish Neurosurgery, 22, ss.558 - 565, 2012.
ISNAD	SHANG, Han-bing vd. "Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas". Turkish Neurosurgery 22/5 (2012), 558-565.