Aim: This study was aimed to present the demographic information about neonates who were hospitalized and followed in our neonatal clinic and who died during follow-up. Material and Methods: In this study, records of neonates who died in our Neonatal Clinic in five years (from 1 January 2007 to 31 December 2011) were evaluated retrospectively. Neonatal mortality rates, perinatal-maternal risk factors and causes of mortality were determined. Results: During the five years, 5491 patients admitted in our clinic and 167 of them died. The mortality rate was 3,04%. The rate of neonates who died in the first 24 hours was 15,6%, whereas 74,9% of them died in the first 7 days of life. The gender distribution of infant deaths was found 46.8% female and 53.2% male. The rate of consanguineous marriage was 28,1%. The rate of mothers <19 years of age was 2,3%; whereas >35 years of age was 14,3%. The rate of neonates who were born <37 weeks of gestational age was 61.6%, whereas 29,9% of them were <28 weeks of gestational age; 37,1% of them were <1000 g of birth weight and 64,6% of them were <2500 g. The most common causes of neonatal mortality were determined as respiratory distress syndrome and prematurity (24.6%), neonatal sepsis (14.9%) and congenital anomalies (10.2%). Other causes were found perinatal asphyxia (8.9%), other respiratory problems (pneumothorax, meconium aspiration syndrome, congenital diaphragm hernia, etc.) (8.9%), cyanotic congenital heart disease (8.4%), metabolic diseases (7.7%), intraventricular hemorrhage (7.7%), necrotizing enterocolitis (3.6%) and others (4.9%). Conclusion: Prematurity and congenital anomalies are still frequent reasons of neonatal deaths. To establish preventable mortality reasons and prevent relevant conditions can be helpful to decrease neonatal mortality rates.