Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children

Şanal, Laser

Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children

Laser ŞANAL (Sağlık Bakanlığı, Ankara Meslek Hastalıkları Hastanesi, Mikrobiyoloji Laboratuvarı, Ankara, Türkiye)

Çocuk Enfeksiyon Dergisi

0 0

Yıl: 2013 Cilt: 7 Sayı: 1 Sayfa Aralığı: 7 - 12 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children

Öz:

Amaç: Bu çalışmada hastanemizde 2009-2011 yıllarıarasında, çocukluk çağı idrar kültürlerinden izole edi- len bakterilerin antibiyotik duyarlılıklarını belirlemeyiamaçladık. Her hastanenin kendi direnç profilini çıkarması ile klinisyenlerin idrar yolu enfeksiyonların- da ampirik antibiyotik seçiminde daha doğru kararlar verebileceğini düşündük. Ayrıca kısıtlı antibiyogram bildirimi ve akılcı antibiyotik kullanımı ile ilgili verilen eğitimler sonrasında direnç oranlarındaki değişimleri gözlemledik. Gereç ve Yöntemler: Bu amaçla 2009-2011 yılları arasında istenen 19138 adet idrar kültürü retrospektif olarak incelendi. Örnekler kanlı agar (premed, İstanbul-Türkiye) ve EMB (premed, İstanbul-Türkiye) besiyerlerine ekildi. Duyarlılık testleri NCCLS kriterleri doğrultusunda disk difüzyon yöntemiyle araştırıldı.Bulgular: İdrar kültürlerinde 2009 yılında 490 (%10.2)hastada, 2010 yılında 377 (%5.6) hastada, 2011 yılın-da ise 905 (%11.7) hastada üreme saptandı. En sık üreyen bakteri her üç yıl için de Escherichia coli’dir.Ampisilin, ko-trimaksazol, ampisilin sulbaktam ve amoksisilin klavulonik asit ampirik kullanımda dikkat edilmesi gereken ve yüksek direnç oranları göz önün-de bulundurulması gereken antibiyotiklerdir. Birinci veikinci kuşak sefalosporinler düşük direnç oranlarınedeniyle ampirik tedavide kullanılabilecek antibiyo-tiklerdir.Sonuç: Antibiyotik direnç oranları bölgeden bölgeyegösterdiği için klinisyenler idrar yolu enfeksiyonların- da ampirik antibiyotik yazarken o bölgenin verilerine göre seçim yaparlarsa tedavilerde başarı şansı dahayüksek olacaktır. Ayrıca akılcı antibiyotik kullanımı ile ilgili verilen eğitimler ve kısıtlı antibiyogram bildirimisonrasında direnç oranlarındaki düşüş umut vericidir. Eğitimlerin her yıl periyodik olarak tekrarlanması fay-dalı olacaktır. (J Pediatr Inf 2013; 7: 7-12)

Anahtar Kelime:

Konular: Enfeksiyon Hastalıkları

Çocukluklardan alınan idrar kültürlerinden izole edilen bakterilerin antibiyotik duyarlılıkları

Öz:

Objective: İn this study we aimed to determine anti-biotic susceptibility of bacteria isolated from child-hood urinary cultures in our hospital between 2009-2011.We thought that clinicians would make betterdecisions in selecting empirical antibiotics in urinarytract infections with every hospital publishing its ownresistance profile. In addition, we observed changesin resistance ratios after training in rationalistic antibi-otic useage and limited antibiogram notifications.Material and Methods: For this purpose, 19138 uri-nary cultures taken between 2009-2011 were anal-ysed, retrospectively. The samples were implantedinto blood agar (Premed, Türkiye) and EMB agar (Premed, Türkiye). Sensitivity tests were researched with the disk diffusion method in accordance with NCCLS criteria. Results: Reproduction was detected in 490 patients (10.2%) in 2009, in 377 patients (5.6%) in 2010, and in 905 patients (11.7%) in 2011. The most repro- duced bacteria was Escherichia coli in all three years. Ampicilline, co-trimaksazole, ampicilline sulbactam and amoxicillin-klavunat were the antibiotics which have to be given attention in using empirical usage and have to be taken into account for their high resis- tance ratios. First and second generation cephalo- sporins are the antibiotics that could be used for the empirical treatments due to their low level of resis- tance ratios. Conclusion: Due to the fact that antibiotic resistance ratios vary from region to region, clinicians would have more chance in treatment if they take into con- sideration the selective region’s data in writing empir-ical antibiotics in treatment of urinary tract infections.Besides,decline in resistance ratios after training inrationalistic antibiotic useage and limited antibiogramnotifications is hopeful. The repetition of trainingcourses periodically each year will be useful.(J Pediatr Inf 2013; 7: 7-12)

Anahtar Kelime:

Konular: Enfeksiyon Hastalıkları

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Cebe A, AyvazA, Yıldız N, Çetinkaya S. Urinary culture results in childhood urinary tract infection in Sivas, Turkey: Which could be the first treatment choice? Van Tıp Dergisi 2008; 15: 7-12.
2. Hacımustafaoğlu M. Urinary Tract Infections in Children. J Pediatr Inf 2011; 5: 258-63. [CrossRef]
3. Yen CW, Chen DH. Urinary tract infection in children. J Microbiol Immunol Infect 1999; 32: 199-205.
4. Bashir MF, Qazi JI, Ahmad N, Riaz S. Diversity of Urinary Tract Pathogens and Drug Resistant Isolates of Escherichia Coli in different age and gender Groups of Pakistanis. Tropical Journal of Pharmaceutical Research 2008; 7: 1025-31. [CrossRef]
5. Yılmaz R, Karaaslan E, Özçetin M, Arslan B, Kılınç M, Kazancı NÖ. Agents of urinary tract infections in children and their anti- biotic susceptibility. Çağdaş Tıp Dergisi 2012; 2: 17-21.
6. Gündüz T, Tosun S, Demirel MM, Ertan P. Antibiotic Resistance In Urinary Tract Infections of Childhood: Five years’ Results. Pamukkale Tıp Dergisi 2008; 1: 87-90.
7. Akram M, Shahid M, Khan AU. Etiology and antibiotic resistan- ce patterns of community-acquired urinary tract infections in J N M C Hospital Aligarh, India. Ann Clin Microbiol Antimicrob 2007; 6: 4. [CrossRef]
8. Ghedira Besbes L, Messaoudi A, Ben Meriem C, Guediche MN. Profile of antimicrobial resistance of agents causing urinary tract infections in children. Tunis Med 2004; 82: 299-305.
9. Bozkurt H, Güdücüoğlu H, Gülmez S, Aygül K, İzci H, Berktaş M. The antimicrobial susceptibility rates of E. coli strains isola- ted from urine cultures of adults group. Van Tıp Dergisi 2005; 12: 232-5.
10. Lutter SA, Currie ML, Mitz LB, Greenbaum LA. Antibiotic resis- tance patterns in children hospitalized for urinary tract infecti- ons. Arch Pediatr Adolesc Med 2005; 159: 924-8. [CrossRef]
11. Eiros Bouza JM, Ochoa Sangrador C. Etiological profile of uri- nary tract infections and antimicrobial susceptibility of urinary pathogens. An Pediatr (Barc) 2007; 67: 461-8. [CrossRef]
12. Borsari AG, Bucher B, Brazzola P, Simonetti GD, Dolina M, Bianchetti MG. Susceptibility of Escherichia coli strains isolated from outpatient children with community-acquired urinary tract infection in southern Switzerland. Clin Ther 2008; 30: 2090-5. [CrossRef]
13. Ferjani A, Mkaddemi H, Tilouche S, et al. Epidemiological and bacteriological characteristics of uropathogen bacteria isolated in a pediatric environment. Arch Pediatr 2011; 18: 230-4. [CrossRef]
14. Boualleque O, Saidani M, Ben Mohamed S, Mzouhi R. Bacteriologic features of urinary tract infections in children in the Sousse area, Tunisia. Tunis Med 2004; 82: 742-6.
15. Mohanna MA, Raja’a YA. Frequency and treatment of urinary tract infection in children subjected to urine culture, in Sana’a, Yemen. J Ayub Med Coll Abbottabad 2005; 17: 20-2.
16. Noemia P, Goldraich Manfroi and angelica Manfroi. Febrile urinary tract infection: Escherichia coli susceptibility to oral antimicrobials. Pediatric Nephrology 2002; 17: 173-6. [CrossRef]
17. Ziyaretli Şanlı K, Türel Ö, Hatipoğlu N, Yılmaz A, Şiraneci R. Gram Negative Bacteria Isolated From Pediatric Urine Samp- les And Their Antibiotic Susceptibility. JOPP Derg 2011; 3: 27- 34.
18. Younis N, Quol K, Al-Momani T, Al-Awaisheh F, Al-Kayed D. Antibiotic resistance in children with recurrent or complicated urinary tract infection JNMA J Nepal Med Assoc 2009; 48: 14-9.

APA	Şanal L (2013). Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. , 7 - 12.
Chicago	Şanal Laser Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. (2013): 7 - 12.
MLA	Şanal Laser Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. , 2013, ss.7 - 12.
AMA	Şanal L Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. . 2013; 7 - 12.
Vancouver	Şanal L Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. . 2013; 7 - 12.
IEEE	Şanal L "Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children." , ss.7 - 12, 2013.
ISNAD	Şanal, Laser. "Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children". (2013), 7-12.

APA	Şanal L (2013). Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. Çocuk Enfeksiyon Dergisi, 7(1), 7 - 12.
Chicago	Şanal Laser Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. Çocuk Enfeksiyon Dergisi 7, no.1 (2013): 7 - 12.
MLA	Şanal Laser Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. Çocuk Enfeksiyon Dergisi, vol.7, no.1, 2013, ss.7 - 12.
AMA	Şanal L Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. Çocuk Enfeksiyon Dergisi. 2013; 7(1): 7 - 12.
Vancouver	Şanal L Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children. Çocuk Enfeksiyon Dergisi. 2013; 7(1): 7 - 12.
IEEE	Şanal L "Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children." Çocuk Enfeksiyon Dergisi, 7, ss.7 - 12, 2013.
ISNAD	Şanal, Laser. "Antibiotic susceptibility of bacteria ısolated from urinary cultures taken from children". Çocuk Enfeksiyon Dergisi 7/1 (2013), 7-12.