Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay

AKKAYA, Nuray; Demir, Esref; kaya, bülent

Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay

Eşref DEMİR, (Akdeniz Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Antalya, Türkiye)

Nuray AKKAYA, (Akdeniz Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Antalya, Türkiye)

Bülent KAYA (Akdeniz Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Antalya, Türkiye)

Turkish Journal of Biology

1 0

Yıl: 2014 Cilt: 38 Sayı: 1 Sayfa Aralığı: 31 - 39 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay

Öz:

Nanogenotoxicity is an emergent field, relevant for estimating the potential genotoxic risk of nanomaterials. In this study we investigated the genotoxic potential of zinc oxide (ZnO, ≤35 and 50 nm) and titanium dioxide (TiO2, 21 and 50 nm) nanoparticles (NPs) in the nuclei of Allium cepa root meristem cells by using a modified alkaline comet assay. ZnO and TiO2 NPs were supplied to cells treated in vitro at 3 different concentrations (10, 100, and 1000 μg/mL). For the comet assay, our results indicate a dose-dependent increment in DNA damage in cells exposed to 100 and 1000 μg/mL of ZnO NPs (≤35 and 50 nm) for percentage of DNA tail (% DNA tail). On the other hand, the results from TiO2 NPs indicated that the DNA damage in the cells exposed to only the highest concentration (1000 μg/mL) of TiO2 NPs (21 nm) is statistically significant in comparison to the control cells, while all concentrations of TiO2 NPs (50 nm) are stat

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Konular: Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Demir E, AKKAYA N, kaya b (2014). Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. , 31 - 39.
Chicago	Demir Esref,AKKAYA Nuray,kaya bülent Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. (2014): 31 - 39.
MLA	Demir Esref,AKKAYA Nuray,kaya bülent Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. , 2014, ss.31 - 39.
AMA	Demir E,AKKAYA N,kaya b Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. . 2014; 31 - 39.
Vancouver	Demir E,AKKAYA N,kaya b Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. . 2014; 31 - 39.
IEEE	Demir E,AKKAYA N,kaya b "Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay." , ss.31 - 39, 2014.
ISNAD	Demir, Esref vd. "Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay". (2014), 31-39.

APA	Demir E, AKKAYA N, kaya b (2014). Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. Turkish Journal of Biology, 38(1), 31 - 39.
Chicago	Demir Esref,AKKAYA Nuray,kaya bülent Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. Turkish Journal of Biology 38, no.1 (2014): 31 - 39.
MLA	Demir Esref,AKKAYA Nuray,kaya bülent Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. Turkish Journal of Biology, vol.38, no.1, 2014, ss.31 - 39.
AMA	Demir E,AKKAYA N,kaya b Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. Turkish Journal of Biology. 2014; 38(1): 31 - 39.
Vancouver	Demir E,AKKAYA N,kaya b Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay. Turkish Journal of Biology. 2014; 38(1): 31 - 39.
IEEE	Demir E,AKKAYA N,kaya b "Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay." Turkish Journal of Biology, 38, ss.31 - 39, 2014.
ISNAD	Demir, Esref vd. "Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay". Turkish Journal of Biology 38/1 (2014), 31-39.