Awareness and use of folic acid among reproductive age and pregnant women
Yıl: 2013 Cilt: 14 Sayı: 2 Sayfa Aralığı: 87 - 91 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Awareness and use of folic acid among reproductive age and pregnant women
Öz: Amaç: Perikonsepsiyonal dönemde ve 1. trimester boyunca folik asit desteği nöral tüp defektini (NTD) azaltmaktadır. Çalışmamızda hastanemize muayene için gelen üreme çağındaki hastalar ile birlikte geb kadınların folik asit kullanımını ve bunlara etki eden faktörleri araştırmayı amaçladık. Gereç ve Yöntemler: Ocak 2012- Haziran 2012 tarihleri arasında hasanemiz Kadın Hastalıkları ve Doğum polikliniğine gelen 817 hastaya (345 gebe, 472 gebe değil) sosyodemografik bilgiler ve folik asit kullanımı ile ilgili soruları içeren bir anket uygulandı. Bulgular: Hastaların % 48.2si folik asidin doğumsal anomalileri önediğini bildirmiştir. Folik asit hakkındaki bilgi ve kullanımı ekonomik düzey ve eğitim düzeyi ile artmaktadır. Katılımcılar folik asit hakkındaki bilgileri en fazla sağlık çalışanlarından öğrendiklerini belirtmiştir. Gebe katılımcılar arasında, gebeliklerin % 88.2i planlı olmasına rağ- men sadece % 14.2de prekonsepsiyonel dönemden başlayarak folik asit kullanılmıştır. Gebeliğin ilk 3 ayında folik asit kullanım oranı ise48.6dır. Gebeliğin hiçbir döneminde folik asit kullanmayanlar % 18.4, kullanıp kullanmadığını bilmeyenler ise % 29.3dür. Çalışmaya katılan sağlık çalışanlarının % 94.4ü folik asidi bilirken, bunların % 28.3de gebelik öncesinde folik asit kullandıkları saptandı. Sonuç: Ülkemizde NTD sıklığının göreceli olarak yüksek olduğu düşünüldüğünde doğurganlık dönemindeki kadınların NTD ve folik asit kullanımı hakkında yeterli bilgiye sahip olmadıkları, bu konuyu iyi bilen sağlık çalışanlarının ise gebelik öncesi dönemde yüksek oran- da folik asit kullanmadıkları görülmüştür. Gebelik öncesi folik asit kullanımının azlığı, üreme çağındaki kadınların folik asitle ilgili daha ayrıntılı bilgilendirilmeleri gerektiğini düşündürmektedir. Bu amaçla öncelikle ebe, hemşire ve aile hekimleri gibi hastaların ilk etapta ulaşacağı sağlık personelinin hastaları bilgilendirme yönünde eğitilmesi ve bu kişilerin, doğurganlık çağındaki tüm kadınlara NTDnin önlenmesinde folik asidin etkisinin duyurulması için çalışmalar yapmaları gerekmektedir. (J Turkish-German Gynecol Assoc 2013; 14: 87-91) %
Anahtar Kelime: Konular:
Üreme çağında ve gebe kadınlarda folik asit hakkında bilgi düzeyi ve kullanım durumu
Öz: Objective: Folic acid supplementation during the pre-conception period and first trimester of pregnancy reduces the incidence of neural tube defects (NTDs). In this study, our aim is to investigate knowledge and use of folic acid among women attending our clinic. Material and Methods: Between January 2012 and June 2012, 817 participants, consisting of 345 pregnant and 472 non-pregnant women, were enrolled in this survey. A questionnaire including socio-demographic information, knowledge and use of folic acid was applied. Results: 48.2% of participants were aware of folic acid for the prevention of congenital anomalies. Knowledge and use of folic acid increase with socio-economic status and educational level. Participants who were already knowledgeable about folic acid cited health care professionals as common sources of information. Although 88.2% of the pregnancies were planned among the currently pregnant women, only 14.2% of them stated that they had used folic acid in the pre-conception period. The use of folic acid during the first trimester among pregnant women was 48.6%. Furthermore, 18.4% of participants had not used folic acid and 29.3% of them had not remembered whether they had or not. Even though 94.4% of health care professionals had heard about folic acid, 28.3% reported that they had used folic acid before pregnancy. Conclusion: It is thought that there is a relatively high incidence of NTD in Turkey, which is due to inadequate information about NTDs and the use of folic acid. Primarily health care professionals such as midwives, nurses and family physicians should aim to inform all reproductive age women about folic acid for the prevention of NTDs, who should be encouraged to take the supplement when planning pregnancy. (J Turkish-German Gynecol Assoc 2013; 14: 87-91)
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- Coskun A, Özdemir Ö. Evaluation of nutrition and mineral-vitamin use during pregnancy. J Turk Soc Obstet Gynecol 2009; 6: 155-70.
- Çoşar E, Köken G, Köken R, Şahin FK, Yeşildağer E, Arıöz DT, et al. Neural tube defects and pregnancy. J Turk Soc Obstet Gynecol. 2009; 6: 193-6.
- Tunçbilek E, Boduroglu K. Nöral tüp defektlerinin önlenmesi. Sürekli Tıp Egitimi Dergisi 1998; 7: 225-7.
- Miner SE, Evrovski J, Cole DE. Clinic chemistry and molecular biol- ogy of homocysteine metabolism: an update. Clin Biochem 1997; 30: 189-201.
- American Academy of Paediatrics, Policy statement. Folic acid for the prevention of neural tube defects. Paediatrics September 1993; 92: 493-4.
- Friel JK, Frecker M, Frase FC. Nutritional patterns of mothers of children with neural tube defects in Newfoundland. Am J Med Genet 1995; 55: 195-9.
- Czeizel AE. Primary prevention of neural tube defects and some other major congenital abnormalities: recommendations for the appropriate use of folic acid during pregnancy. Paediatr Drugs 2000; 2: 437-49.
- Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet 1991; 338: 131-7.
- Van Allen MI, Fraser FC, Dallaire L, Allanson J, McLeod DR, Andermann E, et al. Recommendations on the use of folic acid supplementation to prevent the recurrence of neural tube defects. Clinical Teratology Committee, Canadian College of Medical Geneticists. CMAJ 1993; 149: 1239-43.
- Rasmussen LB, Andersen NL, Andersson G, Lange AP, Rasmussen K, Skak-Iversen L, et al. Folate and neural tube defects. Recommendations from a Danish working group. Dan Med Bull 1998; 45: 213-7.
- Botto LD, Lisi A, Robert-Gnansia E, Erickson JD, Vollset SE, Mastroiacovo P, et al. International retrospective cohort study of neural tube defects in relation to folic acid recommendations: are the recommendations working? BMJ 2005; 330: 571.
- Kondo A, Kamihira O, Shimosuka Y, Okai I, Gotoh M, Ozawa H. Awareness of the role of folic acid, dietary folate intake and plasma folate concentration in Japan. J Obstet Gynaecol Res 2005; 31: 172-7.
- Pérez-Escamilla R. Periconceptional folic acid and neural tube defects: Public health issues. Bull Pan Am Health Organ 1995; 29: 250-63.
- EUROCAT Working Group. 15 Years of Surveillance of Congenital Abnormalities in Europe 1980-1994. Report No. 7. Brussels: Scientific Institute of Public Health-Louis Pasteur, 1997; 50-79.
- Tunçbilek E, Temel E, Özalp İ, Teziç T, Köse R, Üstündağ M, Haznedaroğlu D, Kaptan H. Genetic diseases. Handbook for health personnel 2002. T.C. Ministry of Health General Directory of Health Project, T.R. Ministry of Health General Directorate of Mother and Child Health and Family Planning, Ankara.
- Unusan N. Assesment of Turkish womens knowledge concerning folic acid and prevention of birth defects. Public Health Nutr 2004; 7: 851-55.
- Yüce MA, Candaş T, Sayın NC, Balkanlı-Kaplan P, Güçer F, Yardım T. Olgularımızda gebelik öncesi ve gebelikte folik asit kullanımı. Türk Fertilite Dergisi 2001; 9: 251-7.
- Turgul O, Anli N, Mandiracioglu A, Bati H, Akkol S. The regional campaign for women on awareness of neural tube defects and folic acid in Narlidere, Izmir: a community-based intervention. Eur J Contracept Reprod Health Care 2009; 14: 69-74.
- Baykan Z, Oztürk A, Poyrazoğlu S, Gün I. Awareness, knowledge, and use of folic acid among women: a study from Turkey. Arch Gynecol Obstet 2011; 283: 1249-53.
- Bener A, Al Maadid MG, Al-Bast DA, Al-Marri S. Maternal knowl- edge, attitude and practice on folic acid intake among Arabian Qatari women. Reprod Toxicol 2006; 21: 21-5.
- Nawapun K, Phupong V. Awareness of the benefits of folic acid and prevalence of the use of folic acid supplements to prevent neural tube defects among Thai women. Arch Gynecol Obstet 2007; 276: 53-7.
- Ren A, Zhang L, Li Z, Hao L, Tian Y, Li Z. Awareness and use of folic acid, and blood folate concentrations among pregnant women in northern China-an area with a high prevalence of neural tube defects. Reprod Toxicol 2006; 22: 431-6.
- French MR, Barr SI, Levy-Milne R. Folate intakes and awareness of folate to prevent neural tube defects: a survey of women living in Vancouver, Canada. J Am Diet Assoc 2003; 103: 181-5.
- Forster DA, Wills G, Denning A, Bolger M. The use of folic acid and other vitamins before and during pregnancy in a group of women in Melbourne, Australia. Midwifery 2009; 25: 134-46.
- Bekkers RL, Eskes TK. Periconceptional folic acid intake in Nijmegen, The Netherlands. Lancet 1999; 353: 292.
- Morin P, De Wals P, St-Cyr-Tribble D, Niyonsenga T, Payette H. Pregnancy planning: a determinant of folic acid supplements use for the primary prevention of neural tube defects. Can J Public Health 2002; 93: 259-63.
- Aydınlı K, Çağdaş A, Kayserili H, Kuseyri F, Tükel T, Eriş H, et al. Prekonsepsiyonel folik asit ve multivitamin tedavisinin nonsend- romik nöral tüp defektlerinin yineleme riski üzerine etkisi. Türkiye Klinikleri Jinekoloji-Obstetrik Dergisi 1999; 9: 183-9.
- Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Recomm Rep 1992; 41: 1-7.
- U.S. Preventive Services Task Force. Folic acid for the prevention of neural tube defects: US. preventive services task force recom- mendation statement. Annals of Internal Medicine 2009; 150: 626-31.
- Abdulrazzaq YM, Al-Gazali LI, Bener A, Hossein M, Verghese M, Dawodu A, Folic acid awareness and intake survey in the United Arab Emirates. Reprod Toxicol 2003; 17: 171-6.
- Coll O, Pisa S, Palacio M, Quinto L, Cararach V. Awareness of the use of folic acid to prevent neural tube defects in a Mediterranean area. Eur J Obstet Gynecol Reprod Biol 2004; 115: 173-7.
- Food and Drug Administration. Food standards: amendment of standards of identity for enriched grain products to require addi- tion of folic acid. Federal Register 1996; 61: 8781-97.
- Health Canada. Mandatory fortification of flour and pasta with folic acid- Schedule 25, 1998. Regulatory impact analysis statement.
- The World Health Report. Reducing risks, promoting healthy life. WHO Publications, 2002.
- Hirsch S, Sanchez H, Albala C, de la Maza MP, Barrera G, Leiva L, et al. Colon cancer in Chile before and after the start of the flour fortification program with folic acid. Eur J Gastroenterol Hepatol 2009; 21: 436-9.
- Yajnik CS, Deshpande SS, Jackson AA, Refsum H, Rao S, Fisher DJ, et al. Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study. Diabetologia 2008; 5: 29-38.
| APA | KÖKEN G, DEREBENT UYSAL A, erol o, SAYGIN N, AYIK H, KARACA M (2013). Awareness and use of folic acid among reproductive age and pregnant women. , 87 - 91. |
| Chicago | KÖKEN Gülnihal N.,DEREBENT UYSAL Aysel,erol onur,SAYGIN Nimet,AYIK Hülya,KARACA MEHMET Awareness and use of folic acid among reproductive age and pregnant women. (2013): 87 - 91. |
| MLA | KÖKEN Gülnihal N.,DEREBENT UYSAL Aysel,erol onur,SAYGIN Nimet,AYIK Hülya,KARACA MEHMET Awareness and use of folic acid among reproductive age and pregnant women. , 2013, ss.87 - 91. |
| AMA | KÖKEN G,DEREBENT UYSAL A,erol o,SAYGIN N,AYIK H,KARACA M Awareness and use of folic acid among reproductive age and pregnant women. . 2013; 87 - 91. |
| Vancouver | KÖKEN G,DEREBENT UYSAL A,erol o,SAYGIN N,AYIK H,KARACA M Awareness and use of folic acid among reproductive age and pregnant women. . 2013; 87 - 91. |
| IEEE | KÖKEN G,DEREBENT UYSAL A,erol o,SAYGIN N,AYIK H,KARACA M "Awareness and use of folic acid among reproductive age and pregnant women." , ss.87 - 91, 2013. |
| ISNAD | KÖKEN, Gülnihal N. vd. "Awareness and use of folic acid among reproductive age and pregnant women". (2013), 87-91. |
| APA | KÖKEN G, DEREBENT UYSAL A, erol o, SAYGIN N, AYIK H, KARACA M (2013). Awareness and use of folic acid among reproductive age and pregnant women. Journal of the Turkish-German Gynecological Association, 14(2), 87 - 91. |
| Chicago | KÖKEN Gülnihal N.,DEREBENT UYSAL Aysel,erol onur,SAYGIN Nimet,AYIK Hülya,KARACA MEHMET Awareness and use of folic acid among reproductive age and pregnant women. Journal of the Turkish-German Gynecological Association 14, no.2 (2013): 87 - 91. |
| MLA | KÖKEN Gülnihal N.,DEREBENT UYSAL Aysel,erol onur,SAYGIN Nimet,AYIK Hülya,KARACA MEHMET Awareness and use of folic acid among reproductive age and pregnant women. Journal of the Turkish-German Gynecological Association, vol.14, no.2, 2013, ss.87 - 91. |
| AMA | KÖKEN G,DEREBENT UYSAL A,erol o,SAYGIN N,AYIK H,KARACA M Awareness and use of folic acid among reproductive age and pregnant women. Journal of the Turkish-German Gynecological Association. 2013; 14(2): 87 - 91. |
| Vancouver | KÖKEN G,DEREBENT UYSAL A,erol o,SAYGIN N,AYIK H,KARACA M Awareness and use of folic acid among reproductive age and pregnant women. Journal of the Turkish-German Gynecological Association. 2013; 14(2): 87 - 91. |
| IEEE | KÖKEN G,DEREBENT UYSAL A,erol o,SAYGIN N,AYIK H,KARACA M "Awareness and use of folic acid among reproductive age and pregnant women." Journal of the Turkish-German Gynecological Association, 14, ss.87 - 91, 2013. |
| ISNAD | KÖKEN, Gülnihal N. vd. "Awareness and use of folic acid among reproductive age and pregnant women". Journal of the Turkish-German Gynecological Association 14/2 (2013), 87-91. |
