Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma
Yıl: 2013 Cilt: 14 Sayı: 4 Sayfa Aralığı: 210 - 215 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma
Öz: Amaç: Biz endometrioma bulunan ileri evre endometriozise sahip hastalar (evre 3/4) ve endometrioma dışı non-neoplastik adneksiyel kitle bulunan hastalar arasında preoperatif ortalama trombosit hac- mi (MPV) ve periferik sistemik inflamatuvar yanıt (SIR) belirteçlerinin (nötrofil / lenfosit oranı ve lenfosit/trombosit oranı) değerlerini karşı- laştırdık. Gereç ve Yöntemler: İnfertilite veya adneksiyel kitle ön tanısı ile opere edilen hastalar ile laparaskopik bilateral tubal ligasyon yapılan hastalar çalışmaya dahil edilmiştir. Bulgular: Hemoglobin düzeyi, lökosit sayısı, trombosit sayısı, nötrofil sayısı ve lenfosit sayısı açısından endometrioma saptanan ileri evre endometriosis hastaları (evre 3/4), endometrioma dışı adneksiyel kitle saptanan ve kontrol grubu hastaları arasında anlamlı farklılık saptan- mamıştır (p=0.970, p=0.902, p=0.373, p=0.501 ve p=0.463; sırasıyla). Endometrioma saptanan ileri evre endometriosis hastaları (evre 3/4), endometrioma dışı adneksiyel kitle saptanan ve kontrol grubu has- taları arasında aynı zamanda MPV (p=0.836), nötrofil / lenfosit oranı (NLR) (p=0.555) ve lenfosit/trombosit oranı (PLR) (p=0.358) açısın- dan istatistiksel olarak anlamlı farklılık tespit edilmemiştir. Ameliyat öncesi kanser antijen 125 (Ca 125) seviyeleri operasyonda endometri- oma saptanan (p=0.006) hastalarda anlamlı olarak yüksek bulunmuş- tur. Endometriomaların ortalama boyutu endometrioma dışı kitlelere göre daha düşük tespit edilmiştir (p=0.000). Sonuç: İleri evre endometriozis ve endometrioma bulunan hastaları preoperatif değerlendirme sırasında belirlemek; hastayı bilgilendir- mek ve uygun cerrahi yaklaşımı planlamak için çok önemlidir. Bu çalışmada MPV, NLR ve PLR değerlerininin hücresel veya moleküler düzeyde şiddetli inflamasyon varlığı kanıtlanmış olan ileri evre endo- metriozis hastalarında bu amaç için yararlı olmadığını gösterilmiştir. (J Turkish-German Gynecol Assoc 2013; 14: 210-5)
Anahtar Kelime: Konular:
Endometrioma bulunan ileri evre endometrioziste ortalama trombosit hacmi, nötrofil/lenfosit oranı ve trombosit/lenfosit oranının değerlendirilmesi
Öz: Objective: We compared the preoperative values of mean platelet volume (MPV) and peripheral systemic inflammatory response (SIR) markers (neutrophil/lymphocyte ratio and platelet/lymphocyte ratio) between patients with advanced-stage (stage 3/4) endometriosis hav- ing endometrioma (OMA) and patients with a non-neoplastic adnexal mass other than endometrioma (non-OMA). Material and Methods: Patients who underwent operations with the pre-diagnosis of infertility or adnexal mass and who underwent laparoscopic tubal ligation were included. Results: Haemoglobin levels, leucocyte count, platelet count, neu- trophil count and lymphocyte count were not significantly different between patients with advanced stage endometriosis having OMA, patients with non-OMA and patients in the control group (p=0.970, p=0.902, p=0.373, p=0.501 and p=0.463, respectively). Patients with stage 3/4 endometriosis having OMA, patients with non-OMA and control patients were also not significantly different in terms of MPV (p=0.836), neutrophil/lymphocyte ratio (NLR) (p=0.555) and plate- let/lymphocyte ratio (PLR) (p=0.358). Preoperative cancer antigen 125 (Ca-125) levels were significantly higher in patients with OMA (p=0.006). Mean size of the OMAs was significantly lower than non- OMAs (p=0.000). Conclusion: It is very important to determine advanced stage endo- metriosis and OMAs during preoperative evaluation in order to inform patients and plan an appropriate surgical approach. We demonstrate that MPV, NLR and PLR values are not useful for this purpose in pa- tients with advanced stage endometriosis that are proven to develop severe inflammation at either the cellular or molecular level. (J Turkish-German Gynecol Assoc 2013; 14: 210-5)
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Yavuzcan A, Çağlar M, ÜSTÜN Y, DİLBAZ S, YILDIZ E, ÖZKARA A, KUMRU S, Özdemir İ (2013). Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. , 210 - 215. |
| Chicago | Yavuzcan Ali,Çağlar Mete,ÜSTÜN Yusuf,DİLBAZ Serdar,YILDIZ ELİF,ÖZKARA Atilla,KUMRU Selahattin,Özdemir İsmail Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. (2013): 210 - 215. |
| MLA | Yavuzcan Ali,Çağlar Mete,ÜSTÜN Yusuf,DİLBAZ Serdar,YILDIZ ELİF,ÖZKARA Atilla,KUMRU Selahattin,Özdemir İsmail Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. , 2013, ss.210 - 215. |
| AMA | Yavuzcan A,Çağlar M,ÜSTÜN Y,DİLBAZ S,YILDIZ E,ÖZKARA A,KUMRU S,Özdemir İ Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. . 2013; 210 - 215. |
| Vancouver | Yavuzcan A,Çağlar M,ÜSTÜN Y,DİLBAZ S,YILDIZ E,ÖZKARA A,KUMRU S,Özdemir İ Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. . 2013; 210 - 215. |
| IEEE | Yavuzcan A,Çağlar M,ÜSTÜN Y,DİLBAZ S,YILDIZ E,ÖZKARA A,KUMRU S,Özdemir İ "Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma." , ss.210 - 215, 2013. |
| ISNAD | Yavuzcan, Ali vd. "Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma". (2013), 210-215. |
| APA | Yavuzcan A, Çağlar M, ÜSTÜN Y, DİLBAZ S, YILDIZ E, ÖZKARA A, KUMRU S, Özdemir İ (2013). Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. Journal of the Turkish-German Gynecological Association, 14(4), 210 - 215. |
| Chicago | Yavuzcan Ali,Çağlar Mete,ÜSTÜN Yusuf,DİLBAZ Serdar,YILDIZ ELİF,ÖZKARA Atilla,KUMRU Selahattin,Özdemir İsmail Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. Journal of the Turkish-German Gynecological Association 14, no.4 (2013): 210 - 215. |
| MLA | Yavuzcan Ali,Çağlar Mete,ÜSTÜN Yusuf,DİLBAZ Serdar,YILDIZ ELİF,ÖZKARA Atilla,KUMRU Selahattin,Özdemir İsmail Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. Journal of the Turkish-German Gynecological Association, vol.14, no.4, 2013, ss.210 - 215. |
| AMA | Yavuzcan A,Çağlar M,ÜSTÜN Y,DİLBAZ S,YILDIZ E,ÖZKARA A,KUMRU S,Özdemir İ Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. Journal of the Turkish-German Gynecological Association. 2013; 14(4): 210 - 215. |
| Vancouver | Yavuzcan A,Çağlar M,ÜSTÜN Y,DİLBAZ S,YILDIZ E,ÖZKARA A,KUMRU S,Özdemir İ Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma. Journal of the Turkish-German Gynecological Association. 2013; 14(4): 210 - 215. |
| IEEE | Yavuzcan A,Çağlar M,ÜSTÜN Y,DİLBAZ S,YILDIZ E,ÖZKARA A,KUMRU S,Özdemir İ "Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma." Journal of the Turkish-German Gynecological Association, 14, ss.210 - 215, 2013. |
| ISNAD | Yavuzcan, Ali vd. "Evaluation of mean platelet volume, neutrophil/ lymphocyte ratio and platelet/lymphocyte ratio in advanced stage endometriosis with endometrioma". Journal of the Turkish-German Gynecological Association 14/4 (2013), 210-215. |
