Investigation of some hematological and biochemical parameters in pregnancy and early puerperium

TİFTİK, Ali Muhtar; AKDAĞ, TURAN; SARIYILDIZ, LEVENT

Investigation of some hematological and biochemical parameters in pregnancy and early puerperium

Levent SARIYILDIZ, (Sağlık Bakanlığı, Dr. Faruk Sükan Doğum ve Çocuk Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Konya, Türkiye)

Turan AKDAĞ, (Konya Üniversitesi, Meram Tıp Fakültesi, Biyokimya Anabilim Dalı, Konya, Türkiye)

Ali Muhtar TİFTİK (Konya Üniversitesi, Meram Tıp Fakültesi, Biyokimya Anabilim Dalı, Konya, Türkiye)

Journal of Clinical and Analytical Medicine

5 0

Yıl: 2013 Cilt: 4 Sayı: 2 Sayfa Aralığı: 99 - 103 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Investigation of some hematological and biochemical parameters in pregnancy and early puerperium

Öz:

Amaç: Çalışmanın amacı gebelikte ve doğum sonrasında bazı biyokimyasalparametreleri araştırmaktır. Çalışmada hamilelik boyunca her üç trimesterde ve doğumdan sonra 40. günde lökosit (WBC), eritrosit (RBC), hematokrit(HCT) hemoglobin (HGB), total kolesterol, trigliserid, magnezyum (Mg), kalsiyum (Ca), demir (Fe), total demir bağlama kapasitesi (TIBC) değerlerinin incelenmesi amaçlandı. Gereç ve Yöntem: Çalışma Dr. Faruk Sükan Doğum ve Çocuk Hastanesi gebe polikliniğine başvuran 20-35 yaşları arasında gönüllü metabolik hastalığı olmayan toplam toplam 20 hamile kadın üzerinde gerçekleştirildi. Çalışmaya katılan 20 hamileden doğum öncesi 3 Trimester vedoğumdan sonra 40. gün kan örnekleri alınarak serum WBC, RBC, HCT, HGBve Fe, TIBC, Ca, Mg, trigliserid, total kolesterol kan düzeyleri çalışıldı. Bulgular: RBC, HGB ve HCT seviyelerinde 2. trimesterde önemli bir azalmanın olduğu tespit edildi (p<0,01). Son trimesterde hamileliğin başlangıcındaki seviyeye yakın bir düzeye tekrar ulaşıldığı ve doğumdan sonra RBC ve HGB seviyelerinde 1. trimestere göre önemli bir yükselmenin olduğu tespit edildi (p<0,01). HCT düzeyinin hamileliğin başlangıcındaki düzeyinde olduğu görüldü. TIBCdüzeyinde 2. trimesterde bir artış olduğu, 3. trimester ve doğum sonrasında ise düşmenin devam ettiği ve hamilelik sonrasında en düşük düzeye indiği görüldü. Fe, TIBC, Ca ve Mg seviyelerinde hamilelik boyunca bir azalma görülürken doğumdan sonra ise Ca ve Mg seviyelerinin hamileliğin başlangıcına göre arttığı, Fe düzeyinin ise istatistiksel olarak önemli bir artış göstermesine rağmen hamileliğin başlangıcına kıyasla düşük düzeyde kaldığı tespit edildi (P<0,05). Hamileliğin başlangıcından itibaren doğuma kadar trigliserid, total kolesterol ve WBC düzeylerinde istatistiksel açıdan önemli artışlar izlendi (P<0,01). Doğumdan sonra WBC sayısında istatiksel olarak önemli bir azalmanın meydana geldiği; trigliserid, total kolestrol seviyelerinde ise hamilelikboyunca meydana gelen artışa rağmen doğum sonrasında istatistiksel açıdan önemli bir azalmanın olduğu tespit edildi (P<0,01). Sonuç: Gebelik boyunca meydana gelen metabolik değişiklikler annenin ve fetusun sağlığını etkilediği görülmektedir. Bu parametrelerin hamilelik öncesinden başlamak üzere hamilelik sırasında da araştırılıp rutin olarak incelenmesi, takip edilmesi ve yetersizliklerin önlenmesi hem sağlıklı bir hamilelik dönemi geçirilmesi hemde fetusun normal gelişimi açısından oldukça önemlidir.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Hamilelikte ve erken puerperiumda bazı hematolojik ve biyokimyasal parametrelerin araştırılması

Öz:

Aim and Material and Method: The aim of the study was investigate some biochemical parameters in pregnancy and after birth. In this study, we determined the levels of serum Fe, TIBC, Ca, Mg, triglyceride, total cholesterol, and whole blood WBC, RBC, HCT, HGB in twenty pregnant women whose age ranges were 20-35 yr. The samples were collected before the birth for three times (during three trimester) and after the forty days of birth for only once. Results: Our findings show that levels of triglyceride, total cholesterol and RBC statistically increased ( p<0.01) in pregnant women from the first trimester to the birth. Levels of RBC statistically (p<0.01) decreased more in the forth day after the birth than the first trimester of pregnancy. Although we determined statiscally important low levels of triglyceride, total cholesterol after the birth, we also concluded that those low levels were higher than those at the beginning of pregnancy. Although our findings showed statistically important low levels of Fe, TIBC, Ca and Mg since the first trimester during pregnancy, Ca and Mg levels increased more in the forth day after birth than those at the beginning of pregnancy. Furthermore, Fe levels showed an important increase (p<0.05) but did not reach the levels that were at the beginning of pregnancy. In the second trimester an increase and in the third trimester, in the forth day of the birth decreases in TIBC levels were determined. At the end of the pregnancy, the lowest levels of TIBC were determined. We concluded statistically important (p<0.01) low levels of RBC, HGB and HCT in the second trimester. However, it reached the levels that were at the beginning of pregnancy in the third trimester. Whereas the levels of RBC and HGB in the forth day of the birth were higher than (p<0.01) those at the first trimester, hematocrit levels were similar to the level that were at the beginning of pregnancy. Discussion: Metabolic change that occur during pregnancy affect the health of both mother and fetus. Before and during pregnancy routine investigation and monitoring of the biochemical parameters will be important for prevention of deficiency for the healthy pregnancy and fetus.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SARIYILDIZ L, AKDAĞ T, TİFTİK A (2013). Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. , 99 - 103.
Chicago	SARIYILDIZ LEVENT,AKDAĞ TURAN,TİFTİK Ali Muhtar Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. (2013): 99 - 103.
MLA	SARIYILDIZ LEVENT,AKDAĞ TURAN,TİFTİK Ali Muhtar Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. , 2013, ss.99 - 103.
AMA	SARIYILDIZ L,AKDAĞ T,TİFTİK A Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. . 2013; 99 - 103.
Vancouver	SARIYILDIZ L,AKDAĞ T,TİFTİK A Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. . 2013; 99 - 103.
IEEE	SARIYILDIZ L,AKDAĞ T,TİFTİK A "Investigation of some hematological and biochemical parameters in pregnancy and early puerperium." , ss.99 - 103, 2013.
ISNAD	SARIYILDIZ, LEVENT vd. "Investigation of some hematological and biochemical parameters in pregnancy and early puerperium". (2013), 99-103.

APA	SARIYILDIZ L, AKDAĞ T, TİFTİK A (2013). Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. Journal of Clinical and Analytical Medicine, 4(2), 99 - 103.
Chicago	SARIYILDIZ LEVENT,AKDAĞ TURAN,TİFTİK Ali Muhtar Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. Journal of Clinical and Analytical Medicine 4, no.2 (2013): 99 - 103.
MLA	SARIYILDIZ LEVENT,AKDAĞ TURAN,TİFTİK Ali Muhtar Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. Journal of Clinical and Analytical Medicine, vol.4, no.2, 2013, ss.99 - 103.
AMA	SARIYILDIZ L,AKDAĞ T,TİFTİK A Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. Journal of Clinical and Analytical Medicine. 2013; 4(2): 99 - 103.
Vancouver	SARIYILDIZ L,AKDAĞ T,TİFTİK A Investigation of some hematological and biochemical parameters in pregnancy and early puerperium. Journal of Clinical and Analytical Medicine. 2013; 4(2): 99 - 103.
IEEE	SARIYILDIZ L,AKDAĞ T,TİFTİK A "Investigation of some hematological and biochemical parameters in pregnancy and early puerperium." Journal of Clinical and Analytical Medicine, 4, ss.99 - 103, 2013.
ISNAD	SARIYILDIZ, LEVENT vd. "Investigation of some hematological and biochemical parameters in pregnancy and early puerperium". Journal of Clinical and Analytical Medicine 4/2 (2013), 99-103.