Çocuklarda hematopoetik kök hücrenakli

Mehmet Akif YEŞİLİPEK (Bahçeşehir Üniversitesi Tıp Fakültesi, Çocuk Hematoloji Onkoloji Bilim Dalı, İstanbul, Türkiye)
Türk Pediatri Arşivi
4 0
Yıl: 2014 Cilt: 49 Sayı: 2 Sayfa Aralığı: 91 - 98 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Çocuklarda hematopoetik kök hücrenakli

Öz:
Kemik iliği nakli günümüzde periferik kan ve göbek kordon kanının da kök hücre kaynağı olarak kullanılabilmesi nedeniyle hematopo- etik kök hücre nakli (HKHN) olarak adlandırılmaktadır. Çocuklarda hematolojik malinitelere ek olarak hemoglobinopatiler, immün ye- tersizlikler, kemik iliği yetersizlikleri ve doğuştan metabolik hastalık- lar gibi birçok hastalıkta kesin tedavi yöntemi olarak kullanılmakta- dır. Altta yatan hastalık dışında nakil sürecinde gelişen enfeksiyonlar ve graft versus host hastalığı prognozu etkileyen en önemli etmen- ler olarak sayılabilir. Bu yazıda kök hücre kaynakları, hazırlama te- davileri, çocuklarda HKHN endikasyonları ve nakil sonrası sorunlar konularında özet bilgiler verilmesi amaçlanmıştır. (Türk Ped Arş 2014; 49: 91-8)
Anahtar Kelime:

Konular: Genel ve Dahili Tıp Hücre ve Doku Mühendisliği Transplantasyon Hematoloji Hücre Biyolojisi Pediatri

Hematopoetic stem cell transplantation in children

Öz:
Bone marrow transplantation is called hematopoetic stem cell trans- plantation (HSCT), since peripheral blood and umbilical cord blood can also be used as sources of stem cell currently. In children, bone marrow transplantation is used as a definite treatment method in many diseases including hemoglobinopaties, immune deficiencies, bone marrow failure and congenital metabolic diseases in addition o hematological malignancies. In addition to the underlying dise- ase, the most important factors which have an impact on prognosis nclude infections which develop during the process of transplan- ation and graft-versus-host disease. In this article, it was aimed to give brief information on stem cell sources, preparation therapies, HSCT indications and post-transplantation complications in child- ren. (Türk Ped Arş 2014; 49: 91-8)
Anahtar Kelime:

Konular: Genel ve Dahili Tıp Hücre ve Doku Mühendisliği Transplantasyon Hematoloji Hücre Biyolojisi Pediatri
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA YEŞİLİPEK M (2014). Çocuklarda hematopoetik kök hücrenakli. , 91 - 98.
Chicago YEŞİLİPEK Mehmet Akif Çocuklarda hematopoetik kök hücrenakli. (2014): 91 - 98.
MLA YEŞİLİPEK Mehmet Akif Çocuklarda hematopoetik kök hücrenakli. , 2014, ss.91 - 98.
AMA YEŞİLİPEK M Çocuklarda hematopoetik kök hücrenakli. . 2014; 91 - 98.
Vancouver YEŞİLİPEK M Çocuklarda hematopoetik kök hücrenakli. . 2014; 91 - 98.
IEEE YEŞİLİPEK M "Çocuklarda hematopoetik kök hücrenakli." , ss.91 - 98, 2014.
ISNAD YEŞİLİPEK, Mehmet Akif. "Çocuklarda hematopoetik kök hücrenakli". (2014), 91-98.
APA YEŞİLİPEK M (2014). Çocuklarda hematopoetik kök hücrenakli. Türk Pediatri Arşivi, 49(2), 91 - 98.
Chicago YEŞİLİPEK Mehmet Akif Çocuklarda hematopoetik kök hücrenakli. Türk Pediatri Arşivi 49, no.2 (2014): 91 - 98.
MLA YEŞİLİPEK Mehmet Akif Çocuklarda hematopoetik kök hücrenakli. Türk Pediatri Arşivi, vol.49, no.2, 2014, ss.91 - 98.
AMA YEŞİLİPEK M Çocuklarda hematopoetik kök hücrenakli. Türk Pediatri Arşivi. 2014; 49(2): 91 - 98.
Vancouver YEŞİLİPEK M Çocuklarda hematopoetik kök hücrenakli. Türk Pediatri Arşivi. 2014; 49(2): 91 - 98.
IEEE YEŞİLİPEK M "Çocuklarda hematopoetik kök hücrenakli." Türk Pediatri Arşivi, 49, ss.91 - 98, 2014.
ISNAD YEŞİLİPEK, Mehmet Akif. "Çocuklarda hematopoetik kök hücrenakli". Türk Pediatri Arşivi 49/2 (2014), 91-98.
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