This article is an overview of some of the main issues seen in the context of immigration. As an epilogue, it relates to the other articles in this Special Issue, as well. In particular, the European scene is examined on the basis of re- search conducted over the last decades. There is also an emphasis on family relations and acculturation as well as their interface. Immigration and acculturation over half a century are introduced through a historical perspective noting that multiphasic and multidisciplinary approaches are needed to understand the myriad factors involved. In particular, cultural and developmental viewpoints are promising. Acculturation research has focused on the accul- turating migrant, without due attention to the context of acculturation. In particular, prejudice and discrimination are the greatest challenges. This approach leaves something to be desired, since immigration is a very complex human phenomenon involving issues ranging from micro to macro levels of analysis. While the former concerns individual factors, including the family, the latter includes historic, sociological, economic, and legal aspects and applications. Focusing on the acculturating (or non-acculturating) individual or family without a contextual approach can lead to dispositional attributions, even blaming the victim , that is, social psychological processes not conducive to under- standing and promoting the well-being of the immigrant or the host society. In this context, there is a further need for research to address policies and to suggest solutions for improvement. In particular, concerted efforts that prove to be beneficial for the family, women and children are badly needed. Turkish psychologists and social scientists would do well to attend to these very important topics of study.