Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy

KÖKEN, Reşit; Bucak, Abdulkadir; Kuzu, Selçuk; Ulu, Şahin; AYÇİÇEK, Abdullah

Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy

Şahin ULU, (Kocatepe Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, Afyon, Türkiye)

Abdülkadir BUCAK, (Kocatepe Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, Afyon, Türkiye)

Reşit KÖKEN, (Afyon Kocatepe Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Afyonkarahisar, Türkiye)

Selçuk KUZU, (Kocatepe Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, Afyon, Türkiye)

Abdullah AYÇİÇEK (Kocatepe Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, Afyon, Türkiye)

Van Tıp Dergisi

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Yıl: 2015 Cilt: 22 Sayı: 1 Sayfa Aralığı: 10 - 13 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy

Öz:

Amaç: Adenotonsiller hipertrofi, 2-12 ya ş grubundaki çocuklarda üst solunum yolu obstrüksiyonunun s ık görülen bir nedenidir.Ortalama trombosit hacmi (MPV)trombosit aktivasyonu endekslerinden biridir ve trombosit üretim hızını yans ıtır. Hipoksidurumlar ında MPV ve trombosit üretim hızıartar. Çalış mam ızda, MPV düzeyleri ile adenotonsiller hipertrofi aras ındaki iliş kiyiincelemeyi amaçladık.Gereç ve Yöntem: Adenotonsiller hipertrofi tanıs ısonras ında opere edilen 67 hasta ve 41 ya ş vecinsiyet uyumlu sa ğlıklı birey çalış maya dahiledildi. Ara ş tır ılan belirteçler ve adenotonsillerhipertrofi aras ında kar ş ıla ş tırmalı çok değiş kenlianalizler yapıldı.Bulgular: Hastalar ve kontrol grubu ya ş vecinsiyet aç ıs ından benzerdi. Adenotonsiller hipertrofisi olan hastalar ın MPV ve trombosit da ğılım geniş liği(PDW) düzeyleri kontrol grubuna göre anlamlıolarak yüksek bulundu. (p<0,001, p <0,001) s ıras ı yla.Sonuç: Sonuçta MPV, obstrüksiyon ve hipoksi nedeniyle birçok kardiyovasküler komplikasyonaneden olabilen adenotonsiller hipertrofisinide ğerlendirmede klinisyenler için faydalı olabilir. Buhastalar ın de ğerlendirilmesinde olas ıkomplikasyonlar ıönlemekamac ı ylaoperasyonkarar ını hızlandırmak için MPV de ğerleri göz ardı edilmemelidir.

Anahtar Kelime:

Konular: Cerrahi

Ortalama trombosit hacmi adenotonsiller hipertrofisi olan çocuklarda hipoksi belirteci olarak potansiyel marker

Öz:

Objective: Adenotonsillar hypertrophy is a common cause of upper airway obstruction in children in the agegroup of 2-12 years. It is strongly associated with obstructive manifestations. Mean platelet volume (MPV) isone of the platelet activation markers. It reflects the platelet production rate which increases in hyopxia.Weaimed to evaluate the relationship between MPV levels and adenotonsillar hypertrophy.Materials and Methods: Sixty-seven patients which were operated after the diagnosis of adenotonsillarhypertrophy and 41 age and sex matched healthy subjects were enrolled to the study. Comparativemultivariate analyses between indicator factors and adenotonsillar hypertrophy were conducted. Results: Patients and control group were similar in terms of age and gender. MPV and platelet distributionwidth (PDW) levels of the patients with adenotonsillar hypertrophy were significantly higher than thecontrol group (p<0,001), (p<0,001) respectively.Conclusion: As a conclusion, MPV may be helpful for the clinicians to evaluate adenotonsillar hypertrophywhich may cause many cardiovascular complications due to obstruction and hypoxia. We should notoverlook MPV values while evaluating these patients because it may speed up operation decision to preventits complications.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ulu Ş, Bucak A, KÖKEN R, Kuzu S, AYÇİÇEK A (2015). Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. , 10 - 13.
Chicago	Ulu Şahin,Bucak Abdulkadir,KÖKEN Reşit,Kuzu Selçuk,AYÇİÇEK Abdullah Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. (2015): 10 - 13.
MLA	Ulu Şahin,Bucak Abdulkadir,KÖKEN Reşit,Kuzu Selçuk,AYÇİÇEK Abdullah Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. , 2015, ss.10 - 13.
AMA	Ulu Ş,Bucak A,KÖKEN R,Kuzu S,AYÇİÇEK A Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. . 2015; 10 - 13.
Vancouver	Ulu Ş,Bucak A,KÖKEN R,Kuzu S,AYÇİÇEK A Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. . 2015; 10 - 13.
IEEE	Ulu Ş,Bucak A,KÖKEN R,Kuzu S,AYÇİÇEK A "Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy." , ss.10 - 13, 2015.
ISNAD	Ulu, Şahin vd. "Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy". (2015), 10-13.

APA	Ulu Ş, Bucak A, KÖKEN R, Kuzu S, AYÇİÇEK A (2015). Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. Van Tıp Dergisi, 22(1), 10 - 13.
Chicago	Ulu Şahin,Bucak Abdulkadir,KÖKEN Reşit,Kuzu Selçuk,AYÇİÇEK Abdullah Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. Van Tıp Dergisi 22, no.1 (2015): 10 - 13.
MLA	Ulu Şahin,Bucak Abdulkadir,KÖKEN Reşit,Kuzu Selçuk,AYÇİÇEK Abdullah Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. Van Tıp Dergisi, vol.22, no.1, 2015, ss.10 - 13.
AMA	Ulu Ş,Bucak A,KÖKEN R,Kuzu S,AYÇİÇEK A Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. Van Tıp Dergisi. 2015; 22(1): 10 - 13.
Vancouver	Ulu Ş,Bucak A,KÖKEN R,Kuzu S,AYÇİÇEK A Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy. Van Tıp Dergisi. 2015; 22(1): 10 - 13.
IEEE	Ulu Ş,Bucak A,KÖKEN R,Kuzu S,AYÇİÇEK A "Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy." Van Tıp Dergisi, 22, ss.10 - 13, 2015.
ISNAD	Ulu, Şahin vd. "Mean platelet volume as a potential marker for predicting hypoxia in children with adenotonsillar hypertrophy". Van Tıp Dergisi 22/1 (2015), 10-13.