Objective: Brucellosis is a common zoonosis in many regions throughout the world, especially inTurkey. Infection is frequently transmitted to humans via discharges of infected animals orunpasteurized dairy products. It may lead to complications regarding different organ systems. Inthis retrospective study, it was aimed to understand the clinical and epidemiological properties ofthe brucellosis s: laboratory tests, systemic involvements and complications. Materials and Methods: The clinical and laboratory characteristics of 81 patients with brucellosistreated in our clinic within an 1 year period were investigated retrospectively. Diagnostic criteriawere standard tube agglutination test at a titer of ≥ 1/160 with symptoms suggestive of brucellosis. Results: The mean age was 35.9±15.75 years. Overall, 86.4% of the cases had a history ofingestion of contaminated dairy products. 81.48% of cases were diagnosed in spring andsummer. The main symptoms were fever, arthralgia, sweating, and myalgia. Increased C-reactiveprotein in 47 (58%) patients, increased serum transaminase levels in 19 (23.45%) patients,anemia in 37 (45.7%) patients and leukocytosis in 4 (4.9%) patients were detected.Osteoarticular involvement was present in 8.6% and hepatitis in 8.6%.Conclusion: Our study didn t make novel contribution to the results and related suggestions thathave been previously announced in our country. Brucellosis, which is a systemic disease withmultiorgan involvement presenting with various clinical signs, is a common problem in ourcountry. It should be considered in patients with chronic signs or symptoms associated withmultiorgan involvement, especially in endemic regions.