The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment

Süer, Arif Hikmet; TAŞTAN, Huri; KAZBEK, Baturay Kansu; EKMEKÇİ, Perihan; KAZAK BENGİSUN, ZÜLEYHA; ÖZİŞ, Salih Erpulat

The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment

Perihan EKMEKÇİ, (Ufuk Üniversitesi, Tıp Fakültesi, Dr. Rıdvan Ege Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Ankara, Türkiye)

ZÜLEYHA KAZAK BENGİSUN, (Ufuk Üniversitesi, Tıp Fakültesi, Dr. Rıdvan Ege Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Ankara, Türkiye)

Baturay Kansu KAZBEK, (Ufuk Üniversitesi, Tıp Fakültesi, Dr. Rıdvan Ege Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Ankara, Türkiye)

Salih Erpulat ÖZİŞ, (Ufuk Üniversitesi, Tıp Fakültesi, Dr. Rıdvan Ege Hastanesi, Genel Cerrahi Anabilim Dalı, Ankara, Türkiye)

Huri TAŞTAN, (Ufuk Üniversitesi, Tıp Fakültesi, Dr. Rıdvan Ege Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Ankara, Türkiye)

Arif Hikmet SÜER (Ufuk Üniversitesi, Tıp Fakültesi, Dr. Rıdvan Ege Hastanesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Ankara, Türkiye)

Ağrı

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Yıl: 2012 Cilt: 24 Sayı: 2 Sayfa Aralığı: 63 - 68 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment

Öz:

Amaç: Giderek artan sayıda yapılan günübirlik bir cerrahi girişim olan laparoskopik kolesistektomide ağrı tedavisi önemli bir sorun -dur. Her ne kadar laparoskopik cerrahi günübirlik bir girişim olarak kabul edilse de, hastalar sıklıkla ağrı nedeniyle hospitalize edil-mekte ve bu da opioid tüketimini ve opioidlerin sebep olduğu yan etkileri arttırmaktadır. Bu çalışmanın amacı, laparoskopik kolesis-tektomi sonrasında ağrı tedavisi için hasta kontrollü analjezi (PCA) yönteminde tramadole deksketoprofen trometamol eklenmesi -nin etkinliğini araştırmaktır.Gereç ve Yöntem: Çalışmaya 18-65 yaşları arasında ASA I-II risk grubundan 40 hasta alındı ve kapalı zarf yöntemi ile randomi -ze edildi. Grup TDde 600 mg tramadol ve 100 mg deksketoprofen, Grup Tde ise 600 mg tramadol 100 ml %0.9 normal saline ek-lenerek PCA hazırlandı. Postoperatif dönemde VAS >40 olması durumunda 8 mg lornoksikam iv verildi.Bulgular: Yan etki profli açısından (hipotansiyon, bradikardi, sedasyon) iki grup arasında istatistiksel olarak anlamlı bir fark yok-tu, fakat Grup Tde 4 hasta bulantıdan, 3 hasta ise kusmadan yakındı. Grup TDde opioid tüketimi daha düşük ve hasta memnu -niyeti daha yüksekti.Sonuç: Bu çalışma laparoskopik kolesistektomi sonrasında tramadole deksketoprofen trometamol eklenmesinin hasta kontrollü analjeziyönteminde VAS skorlarını düşürdüğünü, hasta memnuniyetini arttırdığını ve opioid tüketimini azalttığını göstermiştir.

Anahtar Kelime:

Konular: Cerrahi

Laparoskopik kolesistektomi sonrası ağrı tedavisinde hasta kontrollü analjezi yönteminde tramadole deksketoprofen trometamol eklenmesinin etkinliği

Öz:

Objectives: Pain treatment in laparoscopic cholecystectomy, which is performed in increasing numbers as an ambulatoryprocedure, is an important issue.Although laparoscopic cholecystectomy is regarded as an ambulatory procedure, patientsare often hospitalized due to pain and this increases opioid consumption and side efects caused by opioids. Tis study aimsat evaluating the efcacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia (PCA) in post-laparoscopic cholecystectomy pain treatment.Methods: 40 patients in ASA I-II risk groups aged between 18-65 years were enrolled in the study and were randomizedusing closed envelope method. In Group TD 600 mg tramadol and 100 mg dexketoprofen trometamol, in Group T 600 mgtramadol was added to 100 ml 0.9% normal saline for PCA. 8 mg lornoxicam iv was given if VAS >40 in the postoperativeperiod.Results: Tere was no statistically signifcant diference in terms of adverse efects (hypotension, bradycardia, sedation) but inGroup T 4 patients complained of nausea and 3 complained of vomiting. Opioid consumption was lower and patient satisfac -tion was higher in group TD.Conclusion: Tis study has shown that adding dexketoprofen trometamol to tramadol in patient controlled analgesia follow -ing laparoscopic cholecystectomy lowers VAS scores, increases patient satisfaction and decreases opioid consumption.Key words: Dexketoprofen trometamol; laparoscopic cholecystectomy; patient controlled analgesia; postoperative pain.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	EKMEKÇİ P, KAZAK BENGİSUN Z, KAZBEK B, ÖZİŞ S, TAŞTAN H, Süer A (2012). The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. , 63 - 68.
Chicago	EKMEKÇİ Perihan,KAZAK BENGİSUN ZÜLEYHA,KAZBEK Baturay Kansu,ÖZİŞ Salih Erpulat,TAŞTAN Huri,Süer Arif Hikmet The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. (2012): 63 - 68.
MLA	EKMEKÇİ Perihan,KAZAK BENGİSUN ZÜLEYHA,KAZBEK Baturay Kansu,ÖZİŞ Salih Erpulat,TAŞTAN Huri,Süer Arif Hikmet The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. , 2012, ss.63 - 68.
AMA	EKMEKÇİ P,KAZAK BENGİSUN Z,KAZBEK B,ÖZİŞ S,TAŞTAN H,Süer A The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. . 2012; 63 - 68.
Vancouver	EKMEKÇİ P,KAZAK BENGİSUN Z,KAZBEK B,ÖZİŞ S,TAŞTAN H,Süer A The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. . 2012; 63 - 68.
IEEE	EKMEKÇİ P,KAZAK BENGİSUN Z,KAZBEK B,ÖZİŞ S,TAŞTAN H,Süer A "The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment." , ss.63 - 68, 2012.
ISNAD	EKMEKÇİ, Perihan vd. "The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment". (2012), 63-68.

APA	EKMEKÇİ P, KAZAK BENGİSUN Z, KAZBEK B, ÖZİŞ S, TAŞTAN H, Süer A (2012). The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. Ağrı, 24(2), 63 - 68.
Chicago	EKMEKÇİ Perihan,KAZAK BENGİSUN ZÜLEYHA,KAZBEK Baturay Kansu,ÖZİŞ Salih Erpulat,TAŞTAN Huri,Süer Arif Hikmet The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. Ağrı 24, no.2 (2012): 63 - 68.
MLA	EKMEKÇİ Perihan,KAZAK BENGİSUN ZÜLEYHA,KAZBEK Baturay Kansu,ÖZİŞ Salih Erpulat,TAŞTAN Huri,Süer Arif Hikmet The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. Ağrı, vol.24, no.2, 2012, ss.63 - 68.
AMA	EKMEKÇİ P,KAZAK BENGİSUN Z,KAZBEK B,ÖZİŞ S,TAŞTAN H,Süer A The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. Ağrı. 2012; 24(2): 63 - 68.
Vancouver	EKMEKÇİ P,KAZAK BENGİSUN Z,KAZBEK B,ÖZİŞ S,TAŞTAN H,Süer A The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment. Ağrı. 2012; 24(2): 63 - 68.
IEEE	EKMEKÇİ P,KAZAK BENGİSUN Z,KAZBEK B,ÖZİŞ S,TAŞTAN H,Süer A "The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment." Ağrı, 24, ss.63 - 68, 2012.
ISNAD	EKMEKÇİ, Perihan vd. "The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment". Ağrı 24/2 (2012), 63-68.