Yıl: 2015 Cilt: 43 Sayı: 1 Sayfa Aralığı: 60 - 74 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial

Öz:
Amaç Atriyum fibrilasyonlu (AF) hastalar AF kontrolü ve kardiyovasküler (KV) risk profili açısından değerlendirildi.Çalışma planı Türkiye genelinde 40 merkezden toplam 510 hasta (ort. (SS) yaş: 67.1 (12.3) yıl, %55.1i kadın) ile tek vizit temelinde gerçekleştirilen bu çalışmada; hastaların demografik özellikleri, AFnin özellikleri, Avrupa Kalp Ritmi Birliği (EHRA) AF kardiyak semptom sınıflamasına göre semptom sıklığı ve skoru, AF kontrolü, kardiyovasküler (KV) risk profili, AF tedavisi ve uygulanmakta olan tedavi yaklaşımlarının kanıta dayalı kılavuzlarla uyumu değerlendirildi.Bulgular Vizit gününde sinüs ritmi (%10.2) veya kalp hızının (KH) ≤80 vuru/dakika (%29.2) olduğu AF şeklinde olmak üzere AF kontrolü hastaların %39.4ünde mevcuttu. Kalıcı AF (%56.0) en sık gözlenen AF tipi olup, semptomlar V0 öncesi (%78.8) veya V0 esnasında (%56.5) olmak üzere hastaların %89.2sinde tespit edildi. Yaş (%72.4) ve hipertansyion (%70.0) en önemli KV risk faktörleri olarak saptandı. Hız ve ritm kontrol stratejilerinin kayıt vizitinde hastaların sırasıyla %76.5 ve %19.2sinde seçildiği belirlendi. Ort. (SS) EQ-5D skorları VAS için 63.1 (19.8) iken yararlanım endeksi için 0.62 (0.4) olarak bulundu.Sonuç Uluslararası, gözlemsel, kesitsel ve öncü çalışma niteliğindeki REALISE AF çalışmasına Türkiyeden katılan AFli hastaların gerçek yaşamdaki tedavi uygulamalarını yansıtan bu çalışmada, AF kontrolünün optimal düzeyde sağlanamadığı ve bu durumun hastalarda semptom sıklığı, fonksiyonel bozukluk ve yaşam kalitesi değişimlerinin yanı sıra KV olaylar nedeni ile hastanaye başvuru ve müdahale gereksiniminde artışa yol açtığı tespit edilmiştir.
Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Atriyum fibrilasyonlu (AF) hastalarda AF yönetimi ve kardiyovasküler risk profilinin değerlendirilmesi: Uluslararası, gözlemsel, kesitsel REALISE AF çalışması Türkiye verileri

Öz:
Objectives: To assess control of atrial fibrillation (AF) and cardiovascular (CV) risk profile of AF patients with previously established AF therapies. Study design: A total of 510 patients (mean (SD) age, 67.1 (12.3) years, 55.1% females) enrolled from 40 centers across Turkey were evaluated on a single-visit basis in terms of patient demographics, characteristics of underlying AF, the frequency and scoring of symptoms according to European Heart Rhythm Association AF cardiac symptoms classification, control of AF, cardiovascular (CV) risk profile, AF treatment and the consistency of current therapeutic practice with evidence-based guidelines. Results: AF was controlled in 39.4% of patients based on sinus rhythm on the day of visit (10.2%) and AF with HR ≤80 bpm (29.2%). Permanent AF was the most commonly iden- tified type of AF (56.0%). Symptoms were evident in 89.2% of patients either before V0 (78.8%) or at V0 (56.5%). Age (72.4%) and hypertension (70.0%) were the leading CV risk factors. Rate-control and rhythm-control strategies were cho- sen in 76.5 and 19.2% of patients at the enrollment visit. Mean (SD) of EQ-5D scores for VAS and for single index utility were 63.1 (19.8) and 0.62 (0.4), respectively. Conclusion: In this real life survey of AF patients from Tur- key participating in the global contemporary, international, observational, cross-sectional REALISE AF survey, AF was determined to be not optimally controlled, leading patients to experience frequent symptoms, functional impairment and al- tered QoL,as well as frequent hospital admissions for cardio- vascular events and a high requirement for procedures.
Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Diker E, BELLUR G, YILDIZ N, Izgi C, NADİTCH-BRULE L (2015). Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. , 60 - 74.
Chicago Diker Erdem,BELLUR Gökmen,YILDIZ Nurten,Izgi Cemil,NADİTCH-BRULE Lisa Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. (2015): 60 - 74.
MLA Diker Erdem,BELLUR Gökmen,YILDIZ Nurten,Izgi Cemil,NADİTCH-BRULE Lisa Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. , 2015, ss.60 - 74.
AMA Diker E,BELLUR G,YILDIZ N,Izgi C,NADİTCH-BRULE L Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. . 2015; 60 - 74.
Vancouver Diker E,BELLUR G,YILDIZ N,Izgi C,NADİTCH-BRULE L Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. . 2015; 60 - 74.
IEEE Diker E,BELLUR G,YILDIZ N,Izgi C,NADİTCH-BRULE L "Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial." , ss.60 - 74, 2015.
ISNAD Diker, Erdem vd. "Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial". (2015), 60-74.
APA Diker E, BELLUR G, YILDIZ N, Izgi C, NADİTCH-BRULE L (2015). Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. Türk Kardiyoloji Derneği Arşivi, 43(1), 60 - 74.
Chicago Diker Erdem,BELLUR Gökmen,YILDIZ Nurten,Izgi Cemil,NADİTCH-BRULE Lisa Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. Türk Kardiyoloji Derneği Arşivi 43, no.1 (2015): 60 - 74.
MLA Diker Erdem,BELLUR Gökmen,YILDIZ Nurten,Izgi Cemil,NADİTCH-BRULE Lisa Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. Türk Kardiyoloji Derneği Arşivi, vol.43, no.1, 2015, ss.60 - 74.
AMA Diker E,BELLUR G,YILDIZ N,Izgi C,NADİTCH-BRULE L Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. Türk Kardiyoloji Derneği Arşivi. 2015; 43(1): 60 - 74.
Vancouver Diker E,BELLUR G,YILDIZ N,Izgi C,NADİTCH-BRULE L Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial. Türk Kardiyoloji Derneği Arşivi. 2015; 43(1): 60 - 74.
IEEE Diker E,BELLUR G,YILDIZ N,Izgi C,NADİTCH-BRULE L "Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial." Türk Kardiyoloji Derneği Arşivi, 43, ss.60 - 74, 2015.
ISNAD Diker, Erdem vd. "Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial". Türk Kardiyoloji Derneği Arşivi 43/1 (2015), 60-74.