Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation

TUNAOĞLU, F. Sedef; OĞUZ, Deniz; KULA, SERDAR; OLGUNTÜRK, Rana

Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation

F. Sedef TUNAOĞLU, (Gazi Üniversitesi, Tıp Fakültesi, Pediatrik Kardiyoloji Bilim Dalı, Ankara, Türkiye)

Deniz OĞUZ, (Girilmedi)

Serdar KULA, (Girilmedi)

Rana OLGUNTÜRK (Girilmedi)

Gazi Medical Journal

2 0

Yıl: 2002 Cilt: 13 Sayı: 1 Sayfa Aralığı: 35 - 39 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation

Öz:

Bu çalışma romatizmal mitral yetmezliği olan hastaların sol ventrikül sistolik ve diastolik fonksiyonlarını değerlendirmek ve anjiotensin konverting enzim inhibitörü olan enapril tedavisine verdikleri yanıtı değerlendirmek amacıyla planlanmıştır. Yöntem: GÜTF Çocuk Kardiyolojisi Bilim dalında romatizmal mitral yetmezliği nedeniyle digoksin tedavisi alan ve klinik olarak asemptomatik olan 20 hastanın (ört yaş:14.0 ± 0.72 y) başlangıç ve enapril tedavisinin 20.günündeki sol ventrikül sistolik ve diastolik fonksiyonları ekokardiyografık kayıtlardan retrospektif olarak değerlendirilmiştir. Sonuçlar: Enapril tedavisinin ile sol ventrikül diastolik sonu (5.68^.1.19 vs 5.52-^.1.02 cm), sol ventrikül sistol sonu çapı (3.52-^0.98 vs 3.28-^1.04 cm), sol ventriküldiastolsonu volum (161.5±63.2vs 123.9±37.5 mi), sol ventrikül sistol sonu volum (58.8±33.4 vs 41.9-^.16.1 mi), kardiak output (9.08±1.18 vs 8.07±0.87 L/min/m2) düşme saptandı. Erken dolum hızı tepe değeri (1.49-^0.41 vs 1.45±0.57 m/sn), and deselerasyon zamanı (162..3±72.6 vs 156.4±63.l sn) ve izovolemik relaksasyon zamanı (75.4-^20.2 vs 65.16 m/sn) tedavi ile azalırken; A ve E süresi ,total diastolik zamanda uzama saptandı. Yorum: Sonuçlar enalapril tedavisinin ventrikülün ön ve art yükünü etkileyerek sistolik ve diastolik fonksiyonları düzelttiğini ve mitral yetmezlikli hastalarda yararlı olabileceğini göstermiştir.

Anahtar Kelime: Mitral kapak yetmezliği Ventriküler fonksiyon, sağ Romatizmal kalp hastalığı Ekokardiyografi Çocuk Geriyedönük çalışma Ventriküler fonksiyon, sol

Konular: Genel ve Dahili Tıp

Romatizmal mitral yetmezlikli hastaların sol ventrikül sistolik ve diastolik fonksiyonları

Öz:

Purpose: This study was performed to determine the left ventricular systolic and diastolic functions and assess the effects of short-term angiotensin converting inhibition by enalapril in children with rheumatic mitral régurgitation. Methods: Twelve patients (mean age: 14.0 ± 0.72 years) receiving digoxin were evaluated by echocardiography for left ventricular systolic and diastolic functions followed by enalapril treatment for 20 days. Echocardiography was -epeated at the end of the treatment. Results: Left ventricular end-diastolic dimension (5.68±1.19 vs 5.52±1.02 cm), left ventricular end-systolic dimension (3.52±0.98 vs 3.28±1.04 cm), left ventricular end-diastolic volume (161.5^63.2 vs 123.9^.37.5 ml), left ventricular end-systolic volume (58.8±33.4 vs 41.9±16.1 ml), and cardiac output (9.08±1.18 vs 8.07±0.87 L/min/m2) were reduced. Peak early fitting velocity (1.49±0.41 vs 1.45^.0.57 m/sec), and deceleration time (162.3^72.6 vs 156.4^.63.1 sec) were decreased as well as isovolumic relaxation time (75.4±20.2 vs 65.16 m/sec), and A duration, E duration and total diastolic time were prolonged. Conclusion: These data show that enalapril can normalize systolic and diastolic functions by altering loading conditions and be beneficial for children with mitral régurgitation.

Anahtar Kelime: Rheumatic Heart Disease Echocardiography Child Retrospective Studies Ventricular Function, Left Mitral Valve Insufficiency Ventricular Function, Right

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	TUNAOĞLU F, OĞUZ D, KULA S, OLGUNTÜRK R (2002). Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. , 35 - 39.
Chicago	TUNAOĞLU F. Sedef,OĞUZ Deniz,KULA SERDAR,OLGUNTÜRK Rana Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. (2002): 35 - 39.
MLA	TUNAOĞLU F. Sedef,OĞUZ Deniz,KULA SERDAR,OLGUNTÜRK Rana Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. , 2002, ss.35 - 39.
AMA	TUNAOĞLU F,OĞUZ D,KULA S,OLGUNTÜRK R Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. . 2002; 35 - 39.
Vancouver	TUNAOĞLU F,OĞUZ D,KULA S,OLGUNTÜRK R Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. . 2002; 35 - 39.
IEEE	TUNAOĞLU F,OĞUZ D,KULA S,OLGUNTÜRK R "Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation." , ss.35 - 39, 2002.
ISNAD	TUNAOĞLU, F. Sedef vd. "Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation". (2002), 35-39.

APA	TUNAOĞLU F, OĞUZ D, KULA S, OLGUNTÜRK R (2002). Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. Gazi Medical Journal, 13(1), 35 - 39.
Chicago	TUNAOĞLU F. Sedef,OĞUZ Deniz,KULA SERDAR,OLGUNTÜRK Rana Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. Gazi Medical Journal 13, no.1 (2002): 35 - 39.
MLA	TUNAOĞLU F. Sedef,OĞUZ Deniz,KULA SERDAR,OLGUNTÜRK Rana Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. Gazi Medical Journal, vol.13, no.1, 2002, ss.35 - 39.
AMA	TUNAOĞLU F,OĞUZ D,KULA S,OLGUNTÜRK R Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. Gazi Medical Journal. 2002; 13(1): 35 - 39.
Vancouver	TUNAOĞLU F,OĞUZ D,KULA S,OLGUNTÜRK R Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation. Gazi Medical Journal. 2002; 13(1): 35 - 39.
IEEE	TUNAOĞLU F,OĞUZ D,KULA S,OLGUNTÜRK R "Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation." Gazi Medical Journal, 13, ss.35 - 39, 2002.
ISNAD	TUNAOĞLU, F. Sedef vd. "Left ventricular systolic and diastolic functions in children with rheumatic mitral regurgitation". Gazi Medical Journal 13/1 (2002), 35-39.