Aim: To determine the level of problem-solving skills of health college nursing and midwifery students and affecting factors. Methods: No sampling was taken and the entire population (N=492) was included in the study. However, students who refused to participate in the study or failed to fi ll-in the questionnaire form properly (n=65) were excluded from the study. Therefore, a total of 427 (86.8%) students who fi lled in the questionnaire forms properly and volunteered to participate comprised the study group. The data were collected from April 15 to April 25, 2009, using an information form developed by the researchers and the Problem Solving Inventory that was originally developed by Heppner and Peterson, and adapted by Şahin, Şahin and Heppner (1993) into Turkish for use in our country. The percentage calculation, one-way ANOVA, Kruskall Wallis, Mann Whitney U test, student t- test and Tukey test were used in evaluating the data. Results: It was determined that 63.7% of the students were 18-21 years old, 93.0% were female, and 60.2% of the students mothers and 38.6% of their fathers had graduated from primary school. The total score that students received on the Problem Solving Inventory averaged 107.63 ± 12.57. There was a statistically signifi cant relationship between students Problem Solving Inventory point averages and some socio-demographic information such as the departments the students were enrolled in, gender, family type, and where he/she graduated from high school. Conclusion: In this study, the problem solving skills of students who were male, who were studying in nursing department, who graduated from health professions high schools, and who lived in a nuclear family were found to be higher than those of the other students. It is recommended that the curricula of midwifery programs focus further on teaching problem-solving knowledge and skills, and take advantage of problem-based teaching methods.