Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature

MAQBOOL, Mohammad; AJAZ, Hakeem; FARHAT, Mustafa; BABA, Khalil; KHURSHEED, Nayil; BHAT, Salma; MAKHDOOM, Rumana; BASHARAT, Mubeen; RAMZAN, Altaf; AHMAD, Rayees; MOHSIN, Rasool; YAMEEN, Bhat; IQBAL, Lone

Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature

Rumana MAKHDOOM, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Altaf RAMZAN, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Nayil KHURSHEED, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Salma BHAT, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Khalil BABA, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Rasool MOHSIN, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Mubeen BASHARAT, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Bhat YAMEEN, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Rayees AHMAD, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Lone IQBAL, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Mohammad MAQBOOL, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Hakeem AJAZ, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Mustafa FARHAT, (Skims, Department of Pathology, Srinagar, Kashmir, India)

Diğer Yazarlar

Turkish Neurosurgery

1 0

Yıl: 2013 Cilt: 23 Sayı: 6 Sayfa Aralığı: 700 - 706 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature

Öz:

AMAÇ: Tek bir kuruluştan kordomaların klinikopatolojik özelliklerini incelemek. YÖNTEM ve GEREÇLER: Bu çalışma, 2006 ile 2010 yılları arasındaki 5 yıllık bir dönemde Srinagardaki Sher-i-Kashmir Tıp Bilimleri Enstitüsündetanı konmuş 18 kordoma olgusunun retrospektif bir analizidir. BULGULAR: Hastaların ortalama yaşı 46,72 yıldı. Erkeklerin sayısı kadınlardan fazlaydı. En sık tutulan bölge sakrumdu. Histopatolojik olarakolguların çoğu konvansiyonel kordomayken kondroid tipte dört olgu vardı. Kemik metastazıyla gelen tek bir dediferansiye kordoma olgusugörüldü. Çoğu hasta cerrahi ve radyoterapiye iyi sonuç verdi. Bir hastada yerel nüks oldu ve dediferansiye varyantın bulunduğu bir hasta datakip sırasında öldü. SONUÇ: Lokal olarak agresif olmalarına rağmen kordomalar rejeksiyon ve postoperatif radyoterapiyle etkin bir şekilde tedavi edilebilir.

Anahtar Kelime:

Konular: Cerrahi

Kordomanın Klinikopatolojik Özellikleri: Bir Kurum deneyimi ve Literatür derlemesi

Öz:

AIM: To study the clinicopathologic characteristics of chordomas from a single institution.MATERIAL and METHODS: This study is a retrospective analysis of 18 cases of chordomas diagnosed over a period of 5-years at Sher-i-KashmirInstitute of Medical Sciences, Srinagar, from 2006 to 2010.results: The overall mean age of the patients was 46.72 years. Males outnumbered females. Sacrum was the commonest site involved.Histopathologically, the majority of cases were conventional chordoma with four cases of chondroid variety. There was a single case ofdedifferentiated chordoma that presented with bone metastasis. Most patients did well after surgery and radiotherapy. One patient had alocal recurrence and one patient with dedifferentiated variant died on follow-up. CONCLUSION: Though locally aggressive, chordomas are effectively treated with resection and postoperative radiotherapy.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	MAKHDOOM R, RAMZAN A, KHURSHEED N, BHAT S, BABA K, MOHSIN R, BASHARAT M, YAMEEN B, AHMAD R, IQBAL L, MAQBOOL M, AJAZ H, FARHAT M (2013). Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. , 700 - 706.
Chicago	MAKHDOOM Rumana,RAMZAN Altaf,KHURSHEED Nayil,BHAT Salma,BABA Khalil,MOHSIN Rasool,BASHARAT Mubeen,YAMEEN Bhat,AHMAD Rayees,IQBAL Lone,MAQBOOL Mohammad,AJAZ Hakeem,FARHAT Mustafa Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. (2013): 700 - 706.
MLA	MAKHDOOM Rumana,RAMZAN Altaf,KHURSHEED Nayil,BHAT Salma,BABA Khalil,MOHSIN Rasool,BASHARAT Mubeen,YAMEEN Bhat,AHMAD Rayees,IQBAL Lone,MAQBOOL Mohammad,AJAZ Hakeem,FARHAT Mustafa Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. , 2013, ss.700 - 706.
AMA	MAKHDOOM R,RAMZAN A,KHURSHEED N,BHAT S,BABA K,MOHSIN R,BASHARAT M,YAMEEN B,AHMAD R,IQBAL L,MAQBOOL M,AJAZ H,FARHAT M Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. . 2013; 700 - 706.
Vancouver	MAKHDOOM R,RAMZAN A,KHURSHEED N,BHAT S,BABA K,MOHSIN R,BASHARAT M,YAMEEN B,AHMAD R,IQBAL L,MAQBOOL M,AJAZ H,FARHAT M Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. . 2013; 700 - 706.
IEEE	MAKHDOOM R,RAMZAN A,KHURSHEED N,BHAT S,BABA K,MOHSIN R,BASHARAT M,YAMEEN B,AHMAD R,IQBAL L,MAQBOOL M,AJAZ H,FARHAT M "Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature." , ss.700 - 706, 2013.
ISNAD	MAKHDOOM, Rumana vd. "Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature". (2013), 700-706.

APA	MAKHDOOM R, RAMZAN A, KHURSHEED N, BHAT S, BABA K, MOHSIN R, BASHARAT M, YAMEEN B, AHMAD R, IQBAL L, MAQBOOL M, AJAZ H, FARHAT M (2013). Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. Turkish Neurosurgery, 23(6), 700 - 706.
Chicago	MAKHDOOM Rumana,RAMZAN Altaf,KHURSHEED Nayil,BHAT Salma,BABA Khalil,MOHSIN Rasool,BASHARAT Mubeen,YAMEEN Bhat,AHMAD Rayees,IQBAL Lone,MAQBOOL Mohammad,AJAZ Hakeem,FARHAT Mustafa Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. Turkish Neurosurgery 23, no.6 (2013): 700 - 706.
MLA	MAKHDOOM Rumana,RAMZAN Altaf,KHURSHEED Nayil,BHAT Salma,BABA Khalil,MOHSIN Rasool,BASHARAT Mubeen,YAMEEN Bhat,AHMAD Rayees,IQBAL Lone,MAQBOOL Mohammad,AJAZ Hakeem,FARHAT Mustafa Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. Turkish Neurosurgery, vol.23, no.6, 2013, ss.700 - 706.
AMA	MAKHDOOM R,RAMZAN A,KHURSHEED N,BHAT S,BABA K,MOHSIN R,BASHARAT M,YAMEEN B,AHMAD R,IQBAL L,MAQBOOL M,AJAZ H,FARHAT M Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. Turkish Neurosurgery. 2013; 23(6): 700 - 706.
Vancouver	MAKHDOOM R,RAMZAN A,KHURSHEED N,BHAT S,BABA K,MOHSIN R,BASHARAT M,YAMEEN B,AHMAD R,IQBAL L,MAQBOOL M,AJAZ H,FARHAT M Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature. Turkish Neurosurgery. 2013; 23(6): 700 - 706.
IEEE	MAKHDOOM R,RAMZAN A,KHURSHEED N,BHAT S,BABA K,MOHSIN R,BASHARAT M,YAMEEN B,AHMAD R,IQBAL L,MAQBOOL M,AJAZ H,FARHAT M "Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature." Turkish Neurosurgery, 23, ss.700 - 706, 2013.
ISNAD	MAKHDOOM, Rumana vd. "Clinicopathological Characteristics of Chordoma: An Institutional Experience and a Review of the literature". Turkish Neurosurgery 23/6 (2013), 700-706.