Çölyak Hastalığı

KULOĞLU, Zafer

Çölyak Hastalığı

Zafer KULOĞLU (Ankara Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim Dalı, Ankara, Türkiye)

Türkiye Çocuk Hastalıkları Dergisi

15 3

Yıl: 2014 Cilt: 8 Sayı: 2 Sayfa Aralığı: 105 - 111 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Çölyak Hastalığı

Öz:

Çölyak hastalığı (ÇH) oldukça sık görülen bir hastalıktır. Klasik ÇH küçük yaşlarda ortaya çıkarken, atipik hastalık büyükçocuklarda ortaya çıkma eğilimindedir. Değişik klinik bulgular ve tanı- tarama yöntemleri hakkındaki bilgi birikimin artma- sı hastalıktan etkilenen çocukların erken tanı almasına ve uygun müdahalesine olanak sağlamıştır. Serolojik testler dahagüvenilir hale gelmesine rağmen, özellikle 2 yaş altındaki çocuklarda testlerle ilgili sorunlar devam etmektedir. Çölyakhastalarının büyük bir kısmı HLA DQ2 veya DQ8 kodlayan genleri taşırlar. Bu genlerin negatifliği ÇH olasılığını dışlamakiçin yararlı olabilir. Çölyak hastalığına tanı koymak için Glutensiz diyet başlanmadan önce, gluten içeren diyet altında du- odenal biyopsi yapılmalıdır. Glutensiz diyet asemptomatik olan hastalar da dahil ÇH tanısı alan tüm çocuklara verilmelidir.

Anahtar Kelime:

Konular: Pediatri

Celiac Disease

Öz:

Celiac disease is extremely common. The classical presentation tends to occur in younger children, while atypicalpresentations occur at an older age. Knowledge about the varied clinical manifestations together with CD screeningand diagnosis lead to appropriate early diagnosis and intervention in affected children. Although serologic testing hasbecome more reliable, there still remain significant problems with testing, particularly in children under 2 years old.Genes encoding HLA DQ2 or DQ8 are found in the vast majority of those with CD, and negative test results can beuseful in ruling out the disorder. All patients should undergo a duodenal biopsy while on a gluten-containing diet in orderto diagnose CD before a gluten-free diet (GFD) is recommended. A GFD should be offered to all children diagnosed withCD even when perceived as asymptomatic.

Anahtar Kelime:

Konular: Pediatri

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	KULOĞLU Z (2014). Çölyak Hastalığı. , 105 - 111.
Chicago	KULOĞLU Zafer Çölyak Hastalığı. (2014): 105 - 111.
MLA	KULOĞLU Zafer Çölyak Hastalığı. , 2014, ss.105 - 111.
AMA	KULOĞLU Z Çölyak Hastalığı. . 2014; 105 - 111.
Vancouver	KULOĞLU Z Çölyak Hastalığı. . 2014; 105 - 111.
IEEE	KULOĞLU Z "Çölyak Hastalığı." , ss.105 - 111, 2014.
ISNAD	KULOĞLU, Zafer. "Çölyak Hastalığı". (2014), 105-111.

APA	KULOĞLU Z (2014). Çölyak Hastalığı. Türkiye Çocuk Hastalıkları Dergisi, 8(2), 105 - 111.
Chicago	KULOĞLU Zafer Çölyak Hastalığı. Türkiye Çocuk Hastalıkları Dergisi 8, no.2 (2014): 105 - 111.
MLA	KULOĞLU Zafer Çölyak Hastalığı. Türkiye Çocuk Hastalıkları Dergisi, vol.8, no.2, 2014, ss.105 - 111.
AMA	KULOĞLU Z Çölyak Hastalığı. Türkiye Çocuk Hastalıkları Dergisi. 2014; 8(2): 105 - 111.
Vancouver	KULOĞLU Z Çölyak Hastalığı. Türkiye Çocuk Hastalıkları Dergisi. 2014; 8(2): 105 - 111.
IEEE	KULOĞLU Z "Çölyak Hastalığı." Türkiye Çocuk Hastalıkları Dergisi, 8, ss.105 - 111, 2014.
ISNAD	KULOĞLU, Zafer. "Çölyak Hastalığı". Türkiye Çocuk Hastalıkları Dergisi 8/2 (2014), 105-111.