GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction

GÖRGÜLÜ, Şevket; AKSU ÜNAL, Hale; ÇELIK, OMER; ÖNER, Ender; AKSU, HÜSEYİN; BAYCAN, ÖMER FARUK; SATILMIŞOĞLU, Hulusi; erturk, mehmet

GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction

Ender ÖNER, (İstanbul Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim Araştıma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Şevket GÖRGÜLÜ, (Acıbadem Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Adana, Türkiye)

Hale AKSU ÜNAL, (İstanbul Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim Araştıma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Ömer Faruk BAYCAN, (Sağlık Bakanlığı, Muş Devlet Hastanesi, Kardiyoloji Kliniği, Muş, Türkiye)

Mehmet ERTÜRK, (İstanbul Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim Araştıma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Ömer ÇELİK, (İstanbul Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim Araştıma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Hulusi SATILMIŞOĞLU, (İstanbul Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim Araştıma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Hüseyin AKSU (İstanbul Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim Araştıma Hastanesi, Kardiyoloji Kliniği, İstanbul, Türkiye)

Dicle Tıp Dergisi

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Yıl: 2015 Cilt: 42 Sayı: 2 Sayfa Aralığı: 170 - 174 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction

Öz:

Amaç: TIMI ve GRACE risk skorlarının koroner arter hastalığının ciddiyetinin ve yaygınlığının bir göstergesi olanSYNTAX skoru ile korelasyonunu değerlendirmeyi amaçladık. Yöntemler: ST elevasyonsuz miyokard infarktüsü nedeniyle acilimize başvuran ve koroner anjiyografi yapılanhastalar çalışmaya alındı. TIMI ve GRACE risk skorlarıhesaplandı, koroner arter hastalığının ciddiyeti ve yaygınlığı SYNTAX skor algoritması kullanılarak değerlendirildi. Bulgular: 145 hastayı (ortalama yaş 59,41±11.04 yıl,%29 bayan) değerlendirdik. GRACE risk skoru baz alındığında hastane içi ölüm için düşük riskli grupta SYNTAXskoru 12,22±8,70, orta riskli olanlarda 16,66±8,01, yüksek riskli olanlarda 22,48±11,42 idi (ANOVA, p<0,0001).SYNTAX skorları ve GRACE skorları arasında anlamlıpozitif korelasyon vardı (r=0,414, p<0,0001). SYNTAXskoru ile TIMI skoru arasında anlamlı ama daha zayıf birkorelasyon vardı (r=0,271, p=0,001). GRACE skoru yüksek (>33) SYNTAX skoru olan ve olmayan hastalar için iyibir ayırt etme kapasitesi göstermiştir, ROC eğrisi altındaalan 0,804 (CI 0,660-0,948, p=0,002); fakat TIMI skoruayırt etme kapasitesi göstermedi, ROC eğrisi altındakialan 0,532 (CI 0,358-0,749, p=0,749) idi. Sonuç: Yüksek GRACE risk skoru ciddi ve yaygın koroner arter hastalığı olan hastaları öngörmede faydalı olabilir.

Anahtar Kelime:

Konular: Cerrahi

ST yükselmesiz miyokard enfarktüsü hastalarında koroner arter hastalığı yaygınlığının GRACE ve TIMI skorlarıyla öngörülmesi

Öz:

Objective: We aimed to assess the correlation of TIMIand GRACE risk scores with the SYNTAX score as thesurrogate of severity and extent of coronary artery disease.Methods: Patients with non-ST elevation myocardial infarction admitted to our emergency department and undergoing coronary angiography were considered for thisstudy. TIMI and GRACE risk scores were calculated, andcoronary artery disease severity and extension were assessed by using the SYNTAX score algorithm.Results: We assessed 145 patients (mean age59.41±11.04 years, 29% female). Based on the GRACErisk score for in-hospital deaths, the SYNTAX risk scorewas 12.22±8.70 for the low-risk group, 16.66±8.01 for theintermediate-risk group, and 22.48±11.42 for the high-riskgroup (ANOVA, p<0.0001). There were significant positive correlations between the SYNTAX score and GRACEscores (r=0.414, p<0.0001). The SYNTAX score also hada significant but weaker correlation with the TIMI score(r=0.271, p=0.001). The GRACE score showed good discriminatory capacity between the patients with and without a high-risk (>33) SYNTAX score, with an area underthe ROC curve of 0.804 (CI 0.660-0.948, p=0.002); however, the TIMI score showed no predictive capacity andhad an area under the ROC curve of 0.532 (CI 0.358- 0.749, p=0.749). Conclusion: A GRACE score indicating high risk may behelpful in predicting patients with severe extended coronary artery disease

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ÖNER E, GÖRGÜLÜ Ş, AKSU ÜNAL H, BAYCAN Ö, erturk m, ÇELIK O, SATILMIŞOĞLU H, AKSU H (2015). GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. , 170 - 174.
Chicago	ÖNER Ender,GÖRGÜLÜ Şevket,AKSU ÜNAL Hale,BAYCAN ÖMER FARUK,erturk mehmet,ÇELIK OMER,SATILMIŞOĞLU Hulusi,AKSU HÜSEYİN GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. (2015): 170 - 174.
MLA	ÖNER Ender,GÖRGÜLÜ Şevket,AKSU ÜNAL Hale,BAYCAN ÖMER FARUK,erturk mehmet,ÇELIK OMER,SATILMIŞOĞLU Hulusi,AKSU HÜSEYİN GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. , 2015, ss.170 - 174.
AMA	ÖNER E,GÖRGÜLÜ Ş,AKSU ÜNAL H,BAYCAN Ö,erturk m,ÇELIK O,SATILMIŞOĞLU H,AKSU H GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. . 2015; 170 - 174.
Vancouver	ÖNER E,GÖRGÜLÜ Ş,AKSU ÜNAL H,BAYCAN Ö,erturk m,ÇELIK O,SATILMIŞOĞLU H,AKSU H GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. . 2015; 170 - 174.
IEEE	ÖNER E,GÖRGÜLÜ Ş,AKSU ÜNAL H,BAYCAN Ö,erturk m,ÇELIK O,SATILMIŞOĞLU H,AKSU H "GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction." , ss.170 - 174, 2015.
ISNAD	ÖNER, Ender vd. "GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction". (2015), 170-174.

APA	ÖNER E, GÖRGÜLÜ Ş, AKSU ÜNAL H, BAYCAN Ö, erturk m, ÇELIK O, SATILMIŞOĞLU H, AKSU H (2015). GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. Dicle Tıp Dergisi, 42(2), 170 - 174.
Chicago	ÖNER Ender,GÖRGÜLÜ Şevket,AKSU ÜNAL Hale,BAYCAN ÖMER FARUK,erturk mehmet,ÇELIK OMER,SATILMIŞOĞLU Hulusi,AKSU HÜSEYİN GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. Dicle Tıp Dergisi 42, no.2 (2015): 170 - 174.
MLA	ÖNER Ender,GÖRGÜLÜ Şevket,AKSU ÜNAL Hale,BAYCAN ÖMER FARUK,erturk mehmet,ÇELIK OMER,SATILMIŞOĞLU Hulusi,AKSU HÜSEYİN GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. Dicle Tıp Dergisi, vol.42, no.2, 2015, ss.170 - 174.
AMA	ÖNER E,GÖRGÜLÜ Ş,AKSU ÜNAL H,BAYCAN Ö,erturk m,ÇELIK O,SATILMIŞOĞLU H,AKSU H GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. Dicle Tıp Dergisi. 2015; 42(2): 170 - 174.
Vancouver	ÖNER E,GÖRGÜLÜ Ş,AKSU ÜNAL H,BAYCAN Ö,erturk m,ÇELIK O,SATILMIŞOĞLU H,AKSU H GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. Dicle Tıp Dergisi. 2015; 42(2): 170 - 174.
IEEE	ÖNER E,GÖRGÜLÜ Ş,AKSU ÜNAL H,BAYCAN Ö,erturk m,ÇELIK O,SATILMIŞOĞLU H,AKSU H "GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction." Dicle Tıp Dergisi, 42, ss.170 - 174, 2015.
ISNAD	ÖNER, Ender vd. "GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction". Dicle Tıp Dergisi 42/2 (2015), 170-174.