Objective: Susceptibility weighted imaging (SWI) is anovel magnetic resonance technique which uses tissuemagnetic susceptibility differences to generate a uniquecontrast, different from that of spin density, T1, T2, andT2*. The subject of this study is to display the usabilityand the lesion detection sensitivity of the susceptibilityweighted imaging sequence at the various clinic conditionin neuroradiology. Methods: Between February 2009 - May 2009 in Taksim Education and Research Hospital 180 patients, 93(51.7%) females and 87 (48.3%) males and mean ageis 51,6 (range between 5-86), are included to this study.T2* and SWI sequences were applied to all patients additional to conventional magnetic resonance imaging (MRI)sequences by using 1,5 Tesla MRI device (MagnetomAvanto; Siemens, Erlangen, Germany). Patients werecompared with conventional and T2 * sequences in termsof visibility and appearance characteristics of lesions. Results: In our study, we found out that, 12 patients havetraumatic and 10 patients have non-traumatic bleeding,17 patients have mass, 14 patients have micro bleeding spots, 18 patients have vascular malformations, 19patients have ischemic cerebral infarct, 5 patients havecerebral mineral depositions which is related to systemicor neurodegenerative disorders, 8 patients have multiplesclerosis and 48 patients have nonspecific findings. In 30patients no pathologic findings have been found. Conclusion: SWI sequence is a new MRI imaging sequence which is sensitive in detection of pathologies likemacro-micro bleeding, mineral depositions, low-flow vascular lesions, internal architecture of the cranial masses,and also showing hemorrhagic transformations in cerebral infarcts without anatomical detail loss.