An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups

TURĞAL, Mert; KARAAGAOGLU, ERGUN; Aydın, Emine; BEKSAÇ, Mehmet Sinan

An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups

Mehmet Sinan BEKSAÇ, (Boş)

Emine AYDIN, (Boş)

Mert TURĞAL, (Boş)

Ergun KARAAĞAOĞLU (Boş)

GORM:Gynecology Obstetrics & Reproductive Medicine

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Yıl: 2015 Cilt: 21 Sayı: 1 Sayfa Aralığı: 10 - 13 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups

Öz:

AMAÇ: Farklı yüksek riskli gebelik gruplarının değerlendiril- mesinde Beksaç Obstetrik İndeksi (BOİ/BOİp) nin kullanılabi- lirliğinin değerlendirilmesi. GEREÇ VE YÖNTEM: Bu çalışma 3 grup hastadan oluştu. Grup 1 kontrol hastalarını (n=65), Grup 2 MTHFR enzimi için homozigot veya compound heterozigot mutasyonu olan hasta- ları (n=140), Grup 3 ise otoantikor pozitifliği olan (Anti-dsDNA, anti-fosfolipid Ig G/M, anti-kardiolipin Ig G/M, ASMA, APA, ENA, anti-mitokondrial antikor varlığı bulunan) ancak herhangi bir herediter trombofilisi bulunmayan hastaları (n=76) içermek- teydi. Bu çalışmada (Yaşayan çocuk sayısı+π/10)/Gravida ola- rak tanımlanan BOİ farklı yüksek riskli gebelik gruplarında olumsuz klinik durumları göstermek için kullanıldı. BULGULAR: Ortalama BOİp değerleri (±SD) kontrol grubunda 0,41±0,22, MTHFR polimorfizm grubunda 0,29±0,21 ve otoan- tikor grubunda 0,40±0,23 idi. İstatistiksel anlamlılık MTHFR po- limorfizmi grubu ile diğer gruplar arasındaki farktan kaynaklan- maktaydı (p=0,002). SONUÇ: Farklı yüksek riskli gebelik gruplarında risk düzeyinin değerlendirilmesinde kullanılabileceğini gösterdik.

Anahtar Kelime:

Konular: Hematoloji Hücre Biyolojisi

Yüksek Riskli Gebelik Gruplarının Değerlendirilmesi için Bir Obstetrik İndeks

Öz:

OBJECTIVE: To validate the usability of Beksaç Obstetrics Index (BOI/BOIp) in the evaluation of dif- ferent high risk pregnancy groups. STUDY DESIGN: This study is consisted of 3 groups of patients; 1) Pregnancies without MTHFR poly- morphisms (n=65), 2) Pregnancies with methylenetetrahydrofolate reductase (MTHFR; homozygous or compound heterozygous) polymorphisms (n=140), 3) Pregnancies with autoimmune antibody positiv- ity without any other type of hereditary thrombophilia (Anti-dsDNA, anti-phospholipid Ig G/M, anti-car- diolipin Ig G/M, ASMA, APA, ENA, anti-mitochondrial antibodies) (n=76). In this study, BOI which is (number of child +π/10)/Gravida is used in order to demonstrate the risk levels/scale of different high risk pregnancy groups. RESULTS: The mean BOIp (±SD) values are 0,41±0,22; 0,29±0,21; and 0,40±0,23 for Control, MTHFR and Autoimmune groups respectively. We have demonstrated statistically significantly decreased BOIp level in MTHFR group compared to the other groups (p:0,002). CONCLUSION: We have demonstrated that BOI/BOIp can be used in the assessment of risk levels of different high risk pregnancy groups. Keywords: Perinatal morbidity & mortality, High risk pregnancy, Beksac obstetrics index

Anahtar Kelime:

Konular: Hematoloji Hücre Biyolojisi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	BEKSAÇ M, Aydın E, TURĞAL M, KARAAGAOGLU E (2015). An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. , 10 - 13.
Chicago	BEKSAÇ Mehmet Sinan,Aydın Emine,TURĞAL Mert,KARAAGAOGLU ERGUN An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. (2015): 10 - 13.
MLA	BEKSAÇ Mehmet Sinan,Aydın Emine,TURĞAL Mert,KARAAGAOGLU ERGUN An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. , 2015, ss.10 - 13.
AMA	BEKSAÇ M,Aydın E,TURĞAL M,KARAAGAOGLU E An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. . 2015; 10 - 13.
Vancouver	BEKSAÇ M,Aydın E,TURĞAL M,KARAAGAOGLU E An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. . 2015; 10 - 13.
IEEE	BEKSAÇ M,Aydın E,TURĞAL M,KARAAGAOGLU E "An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups." , ss.10 - 13, 2015.
ISNAD	BEKSAÇ, Mehmet Sinan vd. "An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups". (2015), 10-13.

APA	BEKSAÇ M, Aydın E, TURĞAL M, KARAAGAOGLU E (2015). An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. GORM:Gynecology Obstetrics & Reproductive Medicine, 21(1), 10 - 13.
Chicago	BEKSAÇ Mehmet Sinan,Aydın Emine,TURĞAL Mert,KARAAGAOGLU ERGUN An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. GORM:Gynecology Obstetrics & Reproductive Medicine 21, no.1 (2015): 10 - 13.
MLA	BEKSAÇ Mehmet Sinan,Aydın Emine,TURĞAL Mert,KARAAGAOGLU ERGUN An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. GORM:Gynecology Obstetrics & Reproductive Medicine, vol.21, no.1, 2015, ss.10 - 13.
AMA	BEKSAÇ M,Aydın E,TURĞAL M,KARAAGAOGLU E An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. GORM:Gynecology Obstetrics & Reproductive Medicine. 2015; 21(1): 10 - 13.
Vancouver	BEKSAÇ M,Aydın E,TURĞAL M,KARAAGAOGLU E An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups. GORM:Gynecology Obstetrics & Reproductive Medicine. 2015; 21(1): 10 - 13.
IEEE	BEKSAÇ M,Aydın E,TURĞAL M,KARAAGAOGLU E "An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups." GORM:Gynecology Obstetrics & Reproductive Medicine, 21, ss.10 - 13, 2015.
ISNAD	BEKSAÇ, Mehmet Sinan vd. "An Obstetrics Index for the Assessment of Risk Levels of High Risk Pregnancy Groups". GORM:Gynecology Obstetrics & Reproductive Medicine 21/1 (2015), 10-13.