Mikroarray Teknolojisi

BUDAK, Ferah; BAL, Salih Haldun

Mikroarray Teknolojisi

Salih Haldun BAL, (Uludağ Üniversitesi Tıp Fakültesi, Dr. Raşit DURUSOY Kan Merkezi, Bursa, Türkiye)

Ferah BUDAK (Uludağ Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Bursa, Türkiye)

Uludağ Üniversitesi Tıp Fakültesi Dergisi

38 0

Yıl: 2012 Cilt: 38 Sayı: 3 Sayfa Aralığı: 227 - 233 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Mikroarray Teknolojisi

Öz:

Mikroarray teknolojisi, mikroskop lamı gibi cam, plastik veya silikondan yapılmış katı bir yüzey üzerine cDNA, protein gibi yapıların sabitlenmesi ile elde edilen mikroarraylerin kullanıldığı bir yöntemdir. Yüzeye sabitlenen yapının türüne göre DNA mikroarray ve protein mikro- array isimlerini alır. Yüksek verimli teknoloji olarak kabul edilen bu yöntem ile bir deneyde çok büyük miktarda veri elde edilebilir. ÖrneğinDNA mikroarray ile tek bir deneyde insan genomunun tamamı analiz edilebilir. Elde edilen büyük miktardaki verinin değerlendirilebilmesiiçin biyoinformatik desteğe ve yüksek istatistiksel yöntemlere gerek duyulur. Bugün bazı kısıtlılıkları bulunsa da, gelecekte paha biçilmez birdeğere sahip olacaktır. Bu derlemenin amacı gelişmekte olan bu yönteme dikkat çekmektir.

Anahtar Kelime:

Konular: Tıbbi İnformatik Mikrobiyoloji

Microarray Technology

Öz:

Microarray technology is a method which uses a slide made of glass, plastic or silicon. Structures like cDNA, protein etc are spotted onto thisslide. Microarray is divided into two groups as DNA microarray and protein microarray according to the variety of the spotted structure. Thismethod that is accepted as a high throughput method provide large amount of data. For example, human genome can be analyzed with onlyone examination via DNA microarray. Because of huge amount of data, microarray technology needs a powerful bioinformatic support andadvanced statistical methods. Nowadays, despite some limitation of microarray that cause some difficulties, in the near future, it will becomean indispensable and invaluable method. The purpose of this rewiev is to draw attention to this developing method.

Anahtar Kelime:

Konular: Tıbbi İnformatik Mikrobiyoloji

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Bibliyografik

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APA	BAL S, BUDAK F (2012). Mikroarray Teknolojisi. , 227 - 233.
Chicago	BAL Salih Haldun,BUDAK Ferah Mikroarray Teknolojisi. (2012): 227 - 233.
MLA	BAL Salih Haldun,BUDAK Ferah Mikroarray Teknolojisi. , 2012, ss.227 - 233.
AMA	BAL S,BUDAK F Mikroarray Teknolojisi. . 2012; 227 - 233.
Vancouver	BAL S,BUDAK F Mikroarray Teknolojisi. . 2012; 227 - 233.
IEEE	BAL S,BUDAK F "Mikroarray Teknolojisi." , ss.227 - 233, 2012.
ISNAD	BAL, Salih Haldun - BUDAK, Ferah. "Mikroarray Teknolojisi". (2012), 227-233.

APA	BAL S, BUDAK F (2012). Mikroarray Teknolojisi. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 38(3), 227 - 233.
Chicago	BAL Salih Haldun,BUDAK Ferah Mikroarray Teknolojisi. Uludağ Üniversitesi Tıp Fakültesi Dergisi 38, no.3 (2012): 227 - 233.
MLA	BAL Salih Haldun,BUDAK Ferah Mikroarray Teknolojisi. Uludağ Üniversitesi Tıp Fakültesi Dergisi, vol.38, no.3, 2012, ss.227 - 233.
AMA	BAL S,BUDAK F Mikroarray Teknolojisi. Uludağ Üniversitesi Tıp Fakültesi Dergisi. 2012; 38(3): 227 - 233.
Vancouver	BAL S,BUDAK F Mikroarray Teknolojisi. Uludağ Üniversitesi Tıp Fakültesi Dergisi. 2012; 38(3): 227 - 233.
IEEE	BAL S,BUDAK F "Mikroarray Teknolojisi." Uludağ Üniversitesi Tıp Fakültesi Dergisi, 38, ss.227 - 233, 2012.
ISNAD	BAL, Salih Haldun - BUDAK, Ferah. "Mikroarray Teknolojisi". Uludağ Üniversitesi Tıp Fakültesi Dergisi 38/3 (2012), 227-233.