Yıl: 2015 Cilt: 42 Sayı: 3 Sayfa Aralığı: 299 - 304 Metin Dili: Türkçe

Comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of Neutrophil/Lymphocyte ratio

Öz:
Amaç: Bizim çalışmamızdaki amacımız ülkemizde karbonmo- noksit (CO) zehirlenmesinin en sık nedeni olan kömür sobasın- dan kaynaklanan zehirlenmeler ile doğal gaz kaçaklarının yolaçtığı zehirlenmeler arasındaki epidemiyolojik, klinik, laboratu- ar ve prognoz farklılıklarını ortaya koymaktır. Ayrıca CO zehir- lenmelerinde oluşan klinik tablonun şiddeti, prognozu, kompli- kasyonları ile başvuru sırasındaki nötrofil/lenfosit oranı ( NLO )arasındaki ilişkiyi incelemeyi amaçladık. Yöntemler: Bu prospektif çalışmaya Ankara Eğitim ve Araş- tırma Hastanesi Acil Tıp Kliniğine 2009 Ekim2010 Nisantarihleri arasında başvuran akut karbonmonoksit zehirlenmesiolgularının tümü alındı. CO zehirlenmesi tanısı, anemnezindeCO zehirlenmesine neden olabilecek öykünün olması ile birliktekarboksihemoglobin (COHb) konsantrasyonunun % 10nun üs- tünde olması şeklinde konuldu. Çalışmamıza toplam 100 hastadahil edildi. Bulgular: 55 (%55) hasta kömür sobasıyla zehirlenirken, 45(%45) hasta doğal gaz kaynaklı zehirlenmişti. Doğal gazdanzehirlenen grubun ortalama COHb düzeyi anlamlı bir şekildedaha yüksekti (p=0,01). Doğal gaz grubunun ortalama Glas- kow koma skoru (GKS) değeri anlamlı bir şekilde daha düşüktü(p=0,018). Doğal gazdan zehirlenen grupta 17 hastanın HBO(hiperbarik oksi jen) tedavisi ihtiyacı olurken, kömür sobasındanzehirlenen grupta ise sadece 6 hastanın HBO tedavisi ihtiyacıoldu. Doğal gazdan zehirlenen grupta kömür sobasından ze- hirlenen gruba göre anlamlı bir şekilde HBO tedavisi ihtiyacıdaha fazlaydı. (p=0,001) NLO ile COHb oranı, troponin ve GKSdeğerleri arasında istatistiki olarak anlamlı bir ilişki bulunmadı(Sırasıyla; p=0,872, p=0,470, p=0,896). Sonuç: Doğal gaz kaynaklı CO zehirlenmeleri kömür sobasızehirlenmelerine göre daha toksik olabilmektedir. CO zehirlen- melerinde oluşan klinik tablonun şiddeti, prognozu, komplikas- yonları ile başvuru sırasındaki NLO arasında her hangi bir ilişkiyoktur.
Anahtar Kelime:

Kömür sobası ve doğal gaz kaynaklı karbonmonoksit zehirlenmelerinin karşılaştırılması ve Nötrofil/Lenfosit oranının değerlendirilmesi

Öz:
Objective: The aim of our study is to present the epi- demiologic, clinical, laboratory and prognosis differencesbetween the coal stove origin poisoning and natural gasleakages. We also aimed to investigate relationship be- tween the severity of clinical picture, prognosis, complica- tions develop in CO poisoning with neutrophil/lymphocyteratio (NLR) at the initial admission.Methods: All the acute carbon monoxide cases who ap- plied to Ankara Training and Research Hospital Emergen- cy Medicine Clinic between October 2009 and April 2010were included to this prospective study. CO poisoningdiagnosis was made by the history of CO poisoning withcarboxyl hemoglobin (COHb) concentration is over 10%.100 patients were included to our study.Results: Of the patients, 55(55%) were poisoned fromthe coal-stove and 45(45%) from natural gas leakage.The mean COHb level of the natural gas group was sig- nificantly high (p=0.01). The mean value of GCS of thenatural gas group was significantly lower (p=0.018). Thenumber of patients with indication for HBO therapy were17 and 6 in the natural gas group and coal-stove group,respectively, being significantly higher in the natural gasgroup(p=0.001). There was no statistically significant re- lationship between the value of NLR and values of COHb,troponin, and GCS (p=0.872, p=0.470, and p=0.896, re- spectively).Conclusions: Carbon monoxide poisoning from naturalgas leakage is more toxic than that from the coal-stove.There is no relationship between NLR at the time of pre- sentation and the severity of clinical findings, prognosisand complications
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA GÜNAYDIN Y, VURAL K, OK AKÇİL M, KATIRCI Y, KOCAŞABAN ÜÇÜZ D, YİĞİT Y, ÇOŞKUN F (2015). Comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of Neutrophil/Lymphocyte ratio. Dicle Tıp Dergisi, 42(3), 299 - 304.
Chicago GÜNAYDIN YAHYA KEMAL,VURAL Kubilay,OK AKÇİL Mehtap,KATIRCI Yvuz,KOCAŞABAN ÜÇÜZ Dilber,YİĞİT YAVUZ,ÇOŞKUN FİGEN Comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of Neutrophil/Lymphocyte ratio. Dicle Tıp Dergisi 42, no.3 (2015): 299 - 304.
MLA GÜNAYDIN YAHYA KEMAL,VURAL Kubilay,OK AKÇİL Mehtap,KATIRCI Yvuz,KOCAŞABAN ÜÇÜZ Dilber,YİĞİT YAVUZ,ÇOŞKUN FİGEN Comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of Neutrophil/Lymphocyte ratio. Dicle Tıp Dergisi, vol.42, no.3, 2015, ss.299 - 304.
AMA GÜNAYDIN Y,VURAL K,OK AKÇİL M,KATIRCI Y,KOCAŞABAN ÜÇÜZ D,YİĞİT Y,ÇOŞKUN F Comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of Neutrophil/Lymphocyte ratio. Dicle Tıp Dergisi. 2015; 42(3): 299 - 304.
Vancouver GÜNAYDIN Y,VURAL K,OK AKÇİL M,KATIRCI Y,KOCAŞABAN ÜÇÜZ D,YİĞİT Y,ÇOŞKUN F Comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of Neutrophil/Lymphocyte ratio. Dicle Tıp Dergisi. 2015; 42(3): 299 - 304.
IEEE GÜNAYDIN Y,VURAL K,OK AKÇİL M,KATIRCI Y,KOCAŞABAN ÜÇÜZ D,YİĞİT Y,ÇOŞKUN F "Comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of Neutrophil/Lymphocyte ratio." Dicle Tıp Dergisi, 42, ss.299 - 304, 2015.