The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer

ÖZYÜREK AKINCI, Berna; DADALI, YELİZ; KARAKAYA KARABULUT, JALE; DEMİRAĞ, Funda; YILMAZ DEMİRCİ, Nilgün; Şahin Duyar, Sezgi; ÖZMEN, ÖZLEM; Erdoğan, Yurdanur

The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer

Yurdanur ERDOĞAN, (Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Göğüs Cerrahisi Kliniği, Ankara, Türkiye)

Berna ÖZYÜREK AKINCI, (Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Göğüs Cerrahisi Kliniği, Ankara, Türkiye)

Özlem ÖZMEN, (Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Nükleer Tıp Kliniği, Ankara, Türkiye)

Nilgün YILMAZ DEMİRCİ, (Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Göğüs Cerrahisi Kliniği, Ankara, Türkiye)

Yeliz DADALI, (Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Radyoloji Kliniği, Ankara, Türkiye)

Funda DEMİRAĞ, (Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, Ankara, Türkiye)

JALE KARAKAYA KARABULUT, (Hacettepe Üniversitesi, Tıp Fakültesi, Biyoistatistik Anabilim Dalı, Ankara, Türkiye)

Sezgi ŞAHİN DUYAR (Beypazarı Devlet Hastanesi, Göğüs Kliniği, Ankara, Türkiye)

Molecular Imaging and Radionuclide Therapy

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Yıl: 2015 Cilt: 24 Sayı: 2 Sayfa Aralığı: 60 - 65 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer

Öz:

Amaç: Organize pnömoni (OP), respiratuvar bronşiyoller, alveoler kanallar ve alveollerde fibroblastik tıkaçların oluşturduğu polipoid yapılarla karakterize histopatolojik bir durumdur. Radyolojik olarak OPnin tipik, soliter-fokal ve infiltratif olmak üzere 3 karakteristik görünümü vardır. Pozitron Emisyon Tomografi-Bilgisayarlı Tomografiside (PET-BT) yüksek FDG tutulumu malin hastalıklarda olduğu gibi OP gibi benin hastalıklarda da görülebilir. Bu çalışmada maliniteyi taklit eden OPli olgulardaki PET-BT bulgularını değerlendirmeyi amaçladık. Yöntem: Çalışmamızda 2009-2013 yılları arasında Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim Araştırma Hastanesine dış merkezlerden akciğer grafisi veya toraks bilgisayarlı tomografisinde akciğer malinitesinden şüphelenilerek, ileri tetkik ve tedavi amaçlı yönlendirilen ve malinite ön tanısı ile PET-BT çekilen 50 OPli olgu dahil edildi. Retrospektif olarak radyolojik ve klinik özellikleri kayıt edildi. Bulgular: Çalışmaya dahil edilen olguların yaş ortalaması 58,2 idi. Yüzde 96sını (48) erkek hastalar oluşturmaktaydı. Radyolojik olarak PET- BTde 27 (%54) olguda fokal, 10 (%20) olguda hava bronkogramı içeren konsolidasyon (tipik), 1 (%2) olguda infiltratif ve 12 (%24) olguda da diğer görünümler (multiple nodüller, multiple kaviter lezyonlar) saptandı. PETBTde lezyonların maksimum standart tutulum değerlerinin (SUVmax) ortalaması 6,5 olarak hesaplandı. Çalışma grubunun %76sında en az bir istasyonda mediastinal lenf nodu tutulumu saptandı. Lenf nodlarının ortalama SUVmax değeri 3,27 idi. Sonuç: Organize pnömoniler PET-BTde yanlış pozitif sonuçlara yol açabilir. Ancak PET-BT maliniteden şüphe ediliyorsa yapılması gereken invaziv yöntemlere yol gösterici olarak kullanılabilir

Anahtar Kelime:

Konular: Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme

Akciğer Kanserini Taklit Eden Organize Pnömonili Olguların PET/BT Bulgularının Değerlendirilmesi

Öz:

Objective: Organizing pneumonia (OP) is a rare lung condition that is characterized by the presence of polypoid tissues due to fibroblastic plugs within respiratory bronchioles, alveolar ducts and sacs. The three main radiologic patterns of OP include typical, solitary-focal and infiltrative forms. The maximum standardized uptake value (SUVmax) on positron emission tomography-computed tomography (PET/CT) may be high in benign conditions such as OP as well as malignant diseases. The aim of our study was to investigate PET-CT characteristics of OP in patients mimicking lung cancer. Methods: The clinical and radiologic characteristics of 50 patients who were referred to our hospital for PET/CT evaluation due to suspicion of lung malignancy, and who were pathologically diagnosed as OP between 2009 and 2013 were retrospectively reviewed. Results: The mean age of the patients was 58.2 years. Ninety-six percent of patients (48) were male. Radiologic evaluation revealed 27 (54%) focal involvement, 10 (20%) consolidation with air-bronchogram (typical), 1 (2%) infiltrative and 12 (24%) other types of involvement (multiple nodules and cavitary lesions). The mean SUVmax value of the lesions on PET/CT was calculated as 6.5. Mediastinal lymph node involvement (at least one station) was detected in 76% of our study group with a mean SUVmax value of 3.27. Conclusion: OP may cause false positive results on PET/CT. However, PET/CT results may be used as a guide for invasive procedures that should be performed when there is suspicion of malignancy.

Anahtar Kelime:

Konular: Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Erdoğan Y, ÖZYÜREK AKINCI B, ÖZMEN Ö, YILMAZ DEMİRCİ N, DADALI Y, DEMİRAĞ F, KARAKAYA KARABULUT J, Şahin Duyar S (2015). The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. , 60 - 65.
Chicago	Erdoğan Yurdanur,ÖZYÜREK AKINCI Berna,ÖZMEN ÖZLEM,YILMAZ DEMİRCİ Nilgün,DADALI YELİZ,DEMİRAĞ Funda,KARAKAYA KARABULUT JALE,Şahin Duyar Sezgi The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. (2015): 60 - 65.
MLA	Erdoğan Yurdanur,ÖZYÜREK AKINCI Berna,ÖZMEN ÖZLEM,YILMAZ DEMİRCİ Nilgün,DADALI YELİZ,DEMİRAĞ Funda,KARAKAYA KARABULUT JALE,Şahin Duyar Sezgi The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. , 2015, ss.60 - 65.
AMA	Erdoğan Y,ÖZYÜREK AKINCI B,ÖZMEN Ö,YILMAZ DEMİRCİ N,DADALI Y,DEMİRAĞ F,KARAKAYA KARABULUT J,Şahin Duyar S The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. . 2015; 60 - 65.
Vancouver	Erdoğan Y,ÖZYÜREK AKINCI B,ÖZMEN Ö,YILMAZ DEMİRCİ N,DADALI Y,DEMİRAĞ F,KARAKAYA KARABULUT J,Şahin Duyar S The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. . 2015; 60 - 65.
IEEE	Erdoğan Y,ÖZYÜREK AKINCI B,ÖZMEN Ö,YILMAZ DEMİRCİ N,DADALI Y,DEMİRAĞ F,KARAKAYA KARABULUT J,Şahin Duyar S "The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer." , ss.60 - 65, 2015.
ISNAD	Erdoğan, Yurdanur vd. "The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer". (2015), 60-65.

APA	Erdoğan Y, ÖZYÜREK AKINCI B, ÖZMEN Ö, YILMAZ DEMİRCİ N, DADALI Y, DEMİRAĞ F, KARAKAYA KARABULUT J, Şahin Duyar S (2015). The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. Molecular Imaging and Radionuclide Therapy, 24(2), 60 - 65.
Chicago	Erdoğan Yurdanur,ÖZYÜREK AKINCI Berna,ÖZMEN ÖZLEM,YILMAZ DEMİRCİ Nilgün,DADALI YELİZ,DEMİRAĞ Funda,KARAKAYA KARABULUT JALE,Şahin Duyar Sezgi The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. Molecular Imaging and Radionuclide Therapy 24, no.2 (2015): 60 - 65.
MLA	Erdoğan Yurdanur,ÖZYÜREK AKINCI Berna,ÖZMEN ÖZLEM,YILMAZ DEMİRCİ Nilgün,DADALI YELİZ,DEMİRAĞ Funda,KARAKAYA KARABULUT JALE,Şahin Duyar Sezgi The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. Molecular Imaging and Radionuclide Therapy, vol.24, no.2, 2015, ss.60 - 65.
AMA	Erdoğan Y,ÖZYÜREK AKINCI B,ÖZMEN Ö,YILMAZ DEMİRCİ N,DADALI Y,DEMİRAĞ F,KARAKAYA KARABULUT J,Şahin Duyar S The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. Molecular Imaging and Radionuclide Therapy. 2015; 24(2): 60 - 65.
Vancouver	Erdoğan Y,ÖZYÜREK AKINCI B,ÖZMEN Ö,YILMAZ DEMİRCİ N,DADALI Y,DEMİRAĞ F,KARAKAYA KARABULUT J,Şahin Duyar S The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer. Molecular Imaging and Radionuclide Therapy. 2015; 24(2): 60 - 65.
IEEE	Erdoğan Y,ÖZYÜREK AKINCI B,ÖZMEN Ö,YILMAZ DEMİRCİ N,DADALI Y,DEMİRAĞ F,KARAKAYA KARABULUT J,Şahin Duyar S "The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer." Molecular Imaging and Radionuclide Therapy, 24, ss.60 - 65, 2015.
ISNAD	Erdoğan, Yurdanur vd. "The Evaluation of FDG PET/CT Scan Findings in Patients with Organizing Pneumonia Mimicking Lung Cancer". Molecular Imaging and Radionuclide Therapy 24/2 (2015), 60-65.