TY  - JOUR
TI  - Tumour necrosis factor-alpha gene polymorphism (-308 G-A) in Turkish pediatric thrombosis patients
AB  - Tumour necrosis factor-alpha (TNF-alpha) plays an important role in clot formation by activating platelets, monocytes and endothelial cells and inducing procoagulant substances such as negatively charged phospolipids or tissue factor. There is a genetically controlled inter-individual variation of TNF-alpha production.Carrying TNF2 allele could have a slight protective effect against the occurence of stroke in Sickle Cell Disease patients. We aimed to study this polymorphic site in Turkish children with the diagnosis of thrombosis.
AU  - HASİPEK, Metis
AU  - akar, nejat
PY  - 2002
JO  - Turkish Journal of Hematology
VL  - 19
IS  - 1
SN  - 1300-7777
SP  - 39
EP  - 41
DB  - TRDizin
UR  - http://search/yayin/detay/19670
ER  -