TY  - JOUR
TI  - Changes in pressure waves after endoscopic intervention in patients with achalasia: A focus on peristaltic recovery of the esophageal body
AB  - Background/Aims: We conducted the present study to investigate the recovery of peristalsis of the esophageal body and evaluate the pressure changes observed on manometry before and after endoscopic intervention.Materials and Methods: Forty-five patients were diagnosed with achalasia, and 36 received endoscopic or surgical treatment. We collected the data of 24 patients who underwent manometry before and after treatment (pneumatic balloon dilatation, n=7; botulinum toxin injection, n=10; peroral endoscopic myotomy, n=7).Results: The lower esophageal sphincter (LES) resting pressure and nadir LES relaxation pressure decreased regardless of the achalasia subtype or type of endoscopic intervention following treatment (p<0.05). Among patients with a nadir LES relaxation pressure of <4 mmHg, 42.9% (6/14) exhibited partial esophageal peristaltic wave recovery. However, no patients with a nadir LES relaxation pressure of >4 mmHg exhibited peristaltic wave recovery (p=0.024). Of the six patients with peristaltic wave recovery, two had type I achalasia (15.4%), three had type II (33.3%), and one had type III (100.0%). The Eckardt score, symptom duration, and type of intervention were not associated with the recovery of peristaltic waves.Conclusion: Our results suggest that normalization of the nadir LES relaxation pressure can be a predictive factor for the recovery of esophageal peristalsis.
AU  - LEE, Tae Hee
AU  - HONG, Su Jin
AU  - HAN, Jae Pil
AU  - MYUNG, Yu Sik
AU  - KIM, Hyun Soo
AU  - LEE, Joon Seong
AU  - LEE, Moon Sung
AU  - PARK, Se Kyung
AU  - KİM, Shin Hee
AU  - JUNG, Hee Jae
AU  - GOONG, Hyeon Jeong
PY  - 2016
JO  - Turkish Journal of Gastroenterology
VL  - 27
IS  - 1
SN  - 1300-4948
SP  - 4
EP  - 9
DB  - TRDizin
UR  - http://search/yayin/detay/199201
ER  -