Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning

Yıl: 2015 Cilt: 14 Sayı: 2 Sayfa Aralığı: 65 - 69 Metin Dili: Türkçe
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Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning

Öz:
Amaç: Bu retrospektif çalışmada; organofosfat zehirlenmesi olan hastalarda, acil servise başvuru sırasında ölçülen kırmızı küre dağılım genişliği (RDW) ve diğer hematolojik parametrelerin prognostik değerinin araştırılması amaçlanmaktadır. Gereç ve Yöntemler: 2008 ve 2013 yılları arasında acil servise organofosfat zehirlenmesi nedeniyle başvuran 15 yaş ve üzeri tüm hastalar çalışmaya dahil edildi. Hastaların yazılı ve elektronik dosyaları gözden geçirildi. Hematolojik parametreler kaydedildi. Mekanik ventilasyon ihtiyacı ana sonlanım noktası olarak kullanıldı. Bulgular: Çalışmaya toplam 72 hasta dahil edildi. Mekanik ventilasyon desteği verilen hastalar, destek verilmeyen hastalardan istatistiksel anlamlı olarak daha yüksek lökosit ve RDW değerlerine sahipti (sırasıyla, p=0,004 ve p<0,001). Mekanik ventilasyon ihtiyacını tahmin etme gücü açısından, RDW'nin ROC eğrisi altında kalan alanı 0,716 (0,581-0,852 %95 güven aralığı ile, p=0,010) idi. Mekanik ventilasyon ihtiyacını tahmin etmede organofosfat zehirlenmesi olan hastalarda; %14,5 kesim değeri ile RDW %73 sensitiviteye, %70 spesifisiteye ve %91 negatif prediktif değere sahipti. Sonuç: Organofosfat zehirlenmeli hastaların takibinde prognozu tahmin açısından RDW, kolay ve yararlı bir parametre olarak kullanılabilir.
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Organofosfat Zehirlenmeli Hastalarda Kırmızı Küre Dağılım Genişliğinin Prognostik Değeri

Öz:
Aim: The aim of this retrospective study was to investigate the prognostic value of red cell distribution width (RDW) and other hematological parameters measured on admission to the emergency department in patients with organophosphate poisoning.Materials and Methods: All patients aged >=15 years who were admitted to the emergency department from 2008 to 2013 on account of organophosphate poisoning were included in the study. The written and electronic medical charts of the patients were reviewed. Hematological parameters were recorded. Mechanical ventilation requirement was used as the primary endpoint. Results: A total of 72 patients were included in the study for evaluation. Mechanically ventilated patients had significantly higher leukocyte counts and RDW levels than non-ventilated patients (p=0.004 and p<0.001, respectively). The area under the receiver-operating characteristic curve of RDW levels for predicting mechanical ventilation requirement was 0.716 (95% CI: 0.581-0.852, p=0.010). RDW had a sensitivity of 73%, specificity of 70%, and negative predictive value of 91% with a cut-off value of 14.5% in predicting mechanical ventilation requirement in patients with organophosphate poisoning. Conclusion: RDW can be a valuable and easy-to-use parameter in estimating prognosis in the follow-up of patients with organophosphate poisoning. Conclusion: RDW can be a valuable and easy-to-use parameter in estimating prognosis in the follow-up of patients with organophosphate poisoning.
Anahtar Kelime:

Konular:
Fen > Tıp > Acil Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ERGİN M, ÖZER M, GÜNAYDIN Y, DÜNDAR Z, CANDER B, KÖYLÜ R (2015). Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning. Eurasian Journal of Emergency Medicine, 14(2), 65 - 69.
Chicago ERGİN MEHMET,ÖZER MUHAMMET RAŞİT,GÜNAYDIN YAHYA KEMAL,DÜNDAR ZERRİN DEFNE,CANDER BAŞAR,KÖYLÜ Ramazan Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning. Eurasian Journal of Emergency Medicine 14, no.2 (2015): 65 - 69.
MLA ERGİN MEHMET,ÖZER MUHAMMET RAŞİT,GÜNAYDIN YAHYA KEMAL,DÜNDAR ZERRİN DEFNE,CANDER BAŞAR,KÖYLÜ Ramazan Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning. Eurasian Journal of Emergency Medicine, vol.14, no.2, 2015, ss.65 - 69.
AMA ERGİN M,ÖZER M,GÜNAYDIN Y,DÜNDAR Z,CANDER B,KÖYLÜ R Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning. Eurasian Journal of Emergency Medicine. 2015; 14(2): 65 - 69.
Vancouver ERGİN M,ÖZER M,GÜNAYDIN Y,DÜNDAR Z,CANDER B,KÖYLÜ R Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning. Eurasian Journal of Emergency Medicine. 2015; 14(2): 65 - 69.
IEEE ERGİN M,ÖZER M,GÜNAYDIN Y,DÜNDAR Z,CANDER B,KÖYLÜ R "Prognostic Value of Red Cell Distribution Width in Patients with Organophosphate Poisoning." Eurasian Journal of Emergency Medicine, 14, ss.65 - 69, 2015.