An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography
Yıl: 2016 Cilt: 25 Sayı: 3 Sayfa Aralığı: 147 - 149 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography
Öz: Nöroendokrin tümör (NET) şüphesi bulunan 54 yaşındaki kadın hastaya 68Ga-DOTATATE pozitron emisyon tomografisi/bilgisayarlı tomografi (BT) görüntüleme yapıldı. Lomber 3. vertebrada BT görüntülerinde tanımlanan osteolitik lezyonda düşük düzeyde 68Ga-DOTATATE tutulumu izlenmesi nedeniyle NET metastazı açısından şüpheli bulundu. Histopatolojik örnekleme soliter kemik plazmasitomu olarak sonuçlandı. Hasta plazmasitoma nedeniyle lokal eksternal radyoterapiye yönlendirildi. Bu olgu somatostatin reseptörlerini eksprese eden diğer hastalıkların tümör nüksü olarak yanlış raporlanabileceğini ve pozitif bulguların dikkatli değerlendirilmesinin önemini vurgulamaktadır
Anahtar Kelime: Konular:
68Ga-DOTATATE Pozitron Emisyon Tomografi/Bilgisayarlı Tomografi Görüntülemede Nöroendokrin Tümör Metastazını Taklit Eden İnsidental Soliter Kemik Plazmasitomu
Öz: A 54-year-old woman with suspicion of neuroendocrine tumor (NET) was referred for 68Ga-DOTATATE positron emission tomography/computed tomography (CT) imaging due to clinical findings. A well-defined osteolytic lesion on the corpus of the third lumbar vertebra was evident on CT images with mild uptake of 68Ga-DOTATATE, which led to suspicion of NET metastasis. Histopathologic examination revealed solitary plasmacytoma of the bone. The patient received local external radiotherapy for plasmacytoma. This case indicatesthat other diseases expressing somatostatin receptors may be inaccurately reported as tumor recurrence and highlights the importance of meticulous evaluation of positive findings
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- Ambrosini V, Nanni C, Fanti S. The use of gallium-68 labeled somatostatin receptors in PET/CT imaging. PET Clin 2014;9:323-329.
- Sollini M, Erba PA, Fraternali A, Casali M, Di Paolo ML, Froio A, Frasoldati A, Versari A. PET and PET/CT with 68gallium-labeled somatostatin analogues in Non GEP-NETs Tumors. ScientificWorld Journal 2014;2014:194123.
- Dimopoulos MA, Moulopoulos LA, Maniatis A, Alexanian R. Solitary plasmacytoma of bone and asymptomatic multiple myeloma. Blood 2000;96:2037-2044.
- Bataille R, Sany J. Solitary myeloma: clinical and prognostic features of a review of 114 cases. Cancer 1981;48:845-851.
- Has Simsek D, Kuyumcu S, Turkmen C, Sanli Y, Aykan F, Unal S, Adalet I. Can complementary 68Ga-DOTATATE and 18F-FDG PET/CT establish the missing link between histopathology and therapeutic approach in gastroenteropancreatic neuroendocrine tumors? J Nucl Med 2014;55:1811-1817.
- Skoura E, Michopoulou S, Mohmaduvesh M, Panagiotidis E, Al Harbi M, Toumpanakis C, Almukhailed O, Kayani I, Syed R, Navalkissoor S, Ell PJ, Caplin ME, Bomanji J. The Impact of 68Ga-DOTATATE PET/CT Imaging on Management of Patients with Neuroendocrine Tumors: Experience from a National Referral Center in the United Kingdom. J Nucl Med 2016;57:34-40.
- Ambrosini V, Campana D, Bodei L, Nanni C, Castellucci P, Allegri V, Montini GC, Tomassetti P, Paganelli G, Fanti S. 68Ga-DOTANOC PET/ CT clinical impact in patients with neuroendocrine tumors. J Nucl Med 2010;51:669-673.
- Scarsbrook AF, Ganeshan A, Statham J, Thakker RV, Weaver A, Talbot D, Boardman P, Bradley KM, Gleeson FV, Phillips RR. Anatomic and functional imaging of metastatic carcinoid tumors. Radiographics 2007;27:455-477.
- Agool A, Slart RH, Dierckx RA, Kluin PM, Visser L, Jager PL, Vellenga E. Somatostatin receptor scintigraphy might be useful for detecting skeleton abnormalities in patients with multiple myeloma and plasmacytoma. Eur J Nucl Med Mol Imaging 2010;37:124-130.
- Gibril F, Doppman JL, Reynolds JC, Chen CC, Sutliff VE, Yu F, Serrano J, Venzon DJ, Jensen RT. Bone metastases in patients with gastrinomas: a prospective study of bone scanning, somatostatin receptor scanning, and magnetic resonance image in their detection, frequency, location, and effect of their detection on management. J Clin Oncol 1998;16:1040-1053.
- Klinaki I, Al-Nahhas A, Soneji N, Win Z. 68Ga DOTATATE PET/ CT uptake in spinal lesions and MRI correlation on a patient with neuroendocrine tumor: potential pitfalls. Clin Nucl Med 2013;38:e449-453.
- Putzer D, Gabriel M, Henninger B, Kendler D, Uprimny C, Dobrozemsky G, Decristoforo C, Bale RJ, Jaschke W, Virgolini IJ. Bone metastases in patients with neuroendocrine tumor: 68Ga-DOTA- Tyr3-octreotide PET in comparison to CT and bone scintigraphy. J Nucl Med 2009;50:1214-1221.
- Brogsitter C, Hofmockel T, Kotzerke J. (68)Ga DOTATATE uptake in vertebral hemangioma. Clin Nucl Med 2014;39:462-463.
- Skoura E, Alshammari A, Syed R, Sajjan R, Bomanji J. Adolescent With 68Ga DOTATATE-Avid Vertebral Hemangioma Mimicking Metastasis in PET Imaging. Clin Nucl Med 2015;40:e378-379.
- Kuyumcu S, Ozkan ZG, Sanli Y, Yilmaz E, Mudun A, Adalet I, Unal S. Physiological and tumoral uptake of (68)Ga-DOTATATE: standardized uptake values and challenges in interpretation. Ann Nucl Med 2013;27:538-545.
| APA | HAS ŞİMŞEK D, KUYUMCU S, Bilgiç B, IŞIK E, TÜRKMEN C, Adalet I (2016). An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. , 147 - 149. |
| Chicago | HAS ŞİMŞEK DUYGU,KUYUMCU Serkan,Bilgiç Bilge,IŞIK EMİNE GÖKNUR,TÜRKMEN Cüneyt,Adalet Işık An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. (2016): 147 - 149. |
| MLA | HAS ŞİMŞEK DUYGU,KUYUMCU Serkan,Bilgiç Bilge,IŞIK EMİNE GÖKNUR,TÜRKMEN Cüneyt,Adalet Işık An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. , 2016, ss.147 - 149. |
| AMA | HAS ŞİMŞEK D,KUYUMCU S,Bilgiç B,IŞIK E,TÜRKMEN C,Adalet I An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. . 2016; 147 - 149. |
| Vancouver | HAS ŞİMŞEK D,KUYUMCU S,Bilgiç B,IŞIK E,TÜRKMEN C,Adalet I An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. . 2016; 147 - 149. |
| IEEE | HAS ŞİMŞEK D,KUYUMCU S,Bilgiç B,IŞIK E,TÜRKMEN C,Adalet I "An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography." , ss.147 - 149, 2016. |
| ISNAD | HAS ŞİMŞEK, DUYGU vd. "An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography". (2016), 147-149. |
| APA | HAS ŞİMŞEK D, KUYUMCU S, Bilgiç B, IŞIK E, TÜRKMEN C, Adalet I (2016). An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. Molecular Imaging and Radionuclide Therapy, 25(3), 147 - 149. |
| Chicago | HAS ŞİMŞEK DUYGU,KUYUMCU Serkan,Bilgiç Bilge,IŞIK EMİNE GÖKNUR,TÜRKMEN Cüneyt,Adalet Işık An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. Molecular Imaging and Radionuclide Therapy 25, no.3 (2016): 147 - 149. |
| MLA | HAS ŞİMŞEK DUYGU,KUYUMCU Serkan,Bilgiç Bilge,IŞIK EMİNE GÖKNUR,TÜRKMEN Cüneyt,Adalet Işık An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. Molecular Imaging and Radionuclide Therapy, vol.25, no.3, 2016, ss.147 - 149. |
| AMA | HAS ŞİMŞEK D,KUYUMCU S,Bilgiç B,IŞIK E,TÜRKMEN C,Adalet I An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. Molecular Imaging and Radionuclide Therapy. 2016; 25(3): 147 - 149. |
| Vancouver | HAS ŞİMŞEK D,KUYUMCU S,Bilgiç B,IŞIK E,TÜRKMEN C,Adalet I An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography. Molecular Imaging and Radionuclide Therapy. 2016; 25(3): 147 - 149. |
| IEEE | HAS ŞİMŞEK D,KUYUMCU S,Bilgiç B,IŞIK E,TÜRKMEN C,Adalet I "An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography." Molecular Imaging and Radionuclide Therapy, 25, ss.147 - 149, 2016. |
| ISNAD | HAS ŞİMŞEK, DUYGU vd. "An Incidental Solitary Plasmacytoma of Bone Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE Positron Emission Tomography/Computed Tomography". Molecular Imaging and Radionuclide Therapy 25/3 (2016), 147-149. |
