A Study on the Age-Related Changes in Hepatitis B and C Virus Serology
Yıl: 2016 Cilt: 48 Sayı: 1 Sayfa Aralığı: 37 - 41 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
A Study on the Age-Related Changes in Hepatitis B and C Virus Serology
Öz: Amaç: Türkiye'de Hepatit B virüs (HBV) ve Hepatit C virüs (HCV) enfeksiyonu seroprevelansının araştırıldığı çalışmalar sınırlı sayıdadır. Bu çalışmada ulusal hepatit B aşı programı (UHBAP) sonrası ve öncesi dönemde HBV ve HCV seroprevalansının karşılaştırılması ve bu seroprevalanstaki yaşa bağlı değişimin ortaya konulması amaçlanmıştır.Gereç ve Yöntem: Bir hizmet hastanesi laboratuarında 2009 ve 2010 yıllarında çalışılan Hepatit B yüzey antijeni (HBsAg), Hepatit B virüs yüzey antikoru (antiHBs) ve anti-HCV test sonuçları retrospektif olarak incelendi. UHBAP 1998 yılında başladığı için 12 yaş ve daha küçükler UHBAP sonrası dönem olarak kabul edildi.Bulgular: Çalışmanın yapıldığı il nüfusunun yaklaşık %3'üne tekabül eden 3280 HBsAg, 2444 antiHBs ve 3188 anti-HCV test sonucu değerlendirmeye alındı. HBsAg, antiHBs ve anti-HCV pozitifliği sırasıyla %3,2, %36,12 ve %0,97 bulundu. HBsAg ve antiHBs pozitifliği erkeklerde kadınlardan daha yüksekti (p<0,001). Yaş gruplarına göre HBsAg pozitifliği en düşük 0-12 yaş arası, en yüksek 51-60 yaş arası bulundu. UHBAP öncesi dönemde UHBAP sonrası döneme göre HBsAg pozitifliği daha düşüktü (p=0,01). Anti-HCV pozitifliği UHBAP öncesi ve sonrası dönemde benzerdi (p>0,05).Sonuç: UHBAP ile beraber HBsAg seropozitifliği azalmış ve programın daha geniş bir şekilde uygulanmasıyla önümüzdeki yıllarda daha da azalacağı beklenmektedir. HBV ile bağışıklamanın önemi hakkında toplumun farkındalık düzeyini artırıcı faaliyetlere devam edilmelidir
Anahtar Kelime: Konular:
Hepatit B ve C Virüs Serolojisinde Yaşa Bağlı Değişim Hakkında Bir Çalışma
Öz: Objective: There are a limited number of studies on the seroprevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infection in Turkey. This study aimed to compare HBV and HCV seroprevalence rates before and after the implementation of national hepatitis B vaccination program (NHPVP) and to explore age-related changes in the seroprevalences.Materials and Methods: Results of Hepatitis B surface antigen (HBsAg), Hepatitis B virus surface antibody (antiHBs) and antiHCV tests performed during 2009 and 2010 in a state hospital laboratory were reviewed retrospectively. As NHPVP was started in 1998, 12 years of age and younger children were considered post- NHPVP period subjects.Results: A total of 3280 HBsAg, 2444 antiHBs and 3188 anti-HCV test results were reviewed, representing approximately 3% of the population of the city where the study was conducted. HBsAg, antiHBs and anti-HCV positivity were 3.2%, 36.12% and 0.97%, respectively. HBsAg and antiHBs positivity were higher among males (p<0.001). When assessed by age groups, HBsAg positivity was found to be the lowest in the age group 0-12 and highest in the age group 51-60. HBsAg positivity was lower in the postNHPVP period versus pre-NHPVP period (p=0.01). Anti-HCV positivity was similar for pre- and post- NHPVP periods (p>0.05).Conclusion: Owing to the use of NHPVP, HBsAg seropositivity has decreased, and it is expected to decrease further in the next years with a wider implementation of the program. Efforts should be continued to increase the level of awareness in the community for HBV and the importance of immunization
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Guclu E, Öğütlü A, KARABAY O (2016). A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. , 37 - 41. |
| Chicago | Guclu Ertugrul,Öğütlü Aziz,KARABAY OĞUZ A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. (2016): 37 - 41. |
| MLA | Guclu Ertugrul,Öğütlü Aziz,KARABAY OĞUZ A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. , 2016, ss.37 - 41. |
| AMA | Guclu E,Öğütlü A,KARABAY O A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. . 2016; 37 - 41. |
| Vancouver | Guclu E,Öğütlü A,KARABAY O A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. . 2016; 37 - 41. |
| IEEE | Guclu E,Öğütlü A,KARABAY O "A Study on the Age-Related Changes in Hepatitis B and C Virus Serology." , ss.37 - 41, 2016. |
| ISNAD | Guclu, Ertugrul vd. "A Study on the Age-Related Changes in Hepatitis B and C Virus Serology". (2016), 37-41. |
| APA | Guclu E, Öğütlü A, KARABAY O (2016). A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. Eurasian Journal of Medicine, 48(1), 37 - 41. |
| Chicago | Guclu Ertugrul,Öğütlü Aziz,KARABAY OĞUZ A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. Eurasian Journal of Medicine 48, no.1 (2016): 37 - 41. |
| MLA | Guclu Ertugrul,Öğütlü Aziz,KARABAY OĞUZ A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. Eurasian Journal of Medicine, vol.48, no.1, 2016, ss.37 - 41. |
| AMA | Guclu E,Öğütlü A,KARABAY O A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. Eurasian Journal of Medicine. 2016; 48(1): 37 - 41. |
| Vancouver | Guclu E,Öğütlü A,KARABAY O A Study on the Age-Related Changes in Hepatitis B and C Virus Serology. Eurasian Journal of Medicine. 2016; 48(1): 37 - 41. |
| IEEE | Guclu E,Öğütlü A,KARABAY O "A Study on the Age-Related Changes in Hepatitis B and C Virus Serology." Eurasian Journal of Medicine, 48, ss.37 - 41, 2016. |
| ISNAD | Guclu, Ertugrul vd. "A Study on the Age-Related Changes in Hepatitis B and C Virus Serology". Eurasian Journal of Medicine 48/1 (2016), 37-41. |
