Yıl: 2014 Cilt: 44 Sayı: 4 Sayfa Aralığı: 656 - 660 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran

Öz:
Background/aim: Several types of the hepatitis C virus (HCV), with variations in different parts of the genome, have been isolated from different regions of the world. Based on heterogenic sequences in the isolated genome, HCV is classified into different genotypes and subtypes. Data on distribution of HCV genotypes in a certain region could be important to patient management. Therefore, this study was conducted to determine the distribution of HCV in Mashhad, Northeast Iran. Materials and methods: This cross-sectional study was conducted on 103 patients with HCV infections in Mashhad. Among the participants, at least 22 (21.4%) were intravenous drug users. HCV seropositivity was determined by an enzyme-linked immunosorbent assay and was confirmed by reverse transcriptase polymerase chain reaction. HCV-positive samples were selected for HCV genotyping using genotype specific primers. Results: Of 103 subjects, 43 (41.7%) and 34 (33.0%) had genotypes 1a and 3a, respectively. Other genotypes including 1b, 2a, 2b, 3b, and 5a were found in 4 (3.9%), 1 (1.0%), 3 (2.9%), 4 (3.9%), and 1 (1.0%), respectively. Coinfections with 2 genotypes were also observed in 11 (10.7%) patients. Genotyping for 2 (1.9%) of 103 samples did not produce any results. Conclusion: Genotypes 1a and 3a were found to be the most prevalent HCV genotypes in Mashhad, Iran.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA AFSHARI R, NOMANI H, ZANIANI RIYAHI F, NABAVINIA M, MIRBAGHERI Z, MESHKAT M, GERAYLI S, ROSTAMI S, MESHKAT Z (2014). Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. , 656 - 660.
Chicago AFSHARI Reza,NOMANI Hosein,ZANIANI RIYAHI Fatemeh,NABAVINIA Maryam Sadat,MIRBAGHERI Zohreh,MESHKAT Mojtaba,GERAYLI Sina,ROSTAMI Sina,MESHKAT Zahra Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. (2014): 656 - 660.
MLA AFSHARI Reza,NOMANI Hosein,ZANIANI RIYAHI Fatemeh,NABAVINIA Maryam Sadat,MIRBAGHERI Zohreh,MESHKAT Mojtaba,GERAYLI Sina,ROSTAMI Sina,MESHKAT Zahra Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. , 2014, ss.656 - 660.
AMA AFSHARI R,NOMANI H,ZANIANI RIYAHI F,NABAVINIA M,MIRBAGHERI Z,MESHKAT M,GERAYLI S,ROSTAMI S,MESHKAT Z Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. . 2014; 656 - 660.
Vancouver AFSHARI R,NOMANI H,ZANIANI RIYAHI F,NABAVINIA M,MIRBAGHERI Z,MESHKAT M,GERAYLI S,ROSTAMI S,MESHKAT Z Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. . 2014; 656 - 660.
IEEE AFSHARI R,NOMANI H,ZANIANI RIYAHI F,NABAVINIA M,MIRBAGHERI Z,MESHKAT M,GERAYLI S,ROSTAMI S,MESHKAT Z "Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran." , ss.656 - 660, 2014.
ISNAD AFSHARI, Reza vd. "Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran". (2014), 656-660.
APA AFSHARI R, NOMANI H, ZANIANI RIYAHI F, NABAVINIA M, MIRBAGHERI Z, MESHKAT M, GERAYLI S, ROSTAMI S, MESHKAT Z (2014). Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. Turkish Journal of Medical Sciences, 44(4), 656 - 660.
Chicago AFSHARI Reza,NOMANI Hosein,ZANIANI RIYAHI Fatemeh,NABAVINIA Maryam Sadat,MIRBAGHERI Zohreh,MESHKAT Mojtaba,GERAYLI Sina,ROSTAMI Sina,MESHKAT Zahra Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. Turkish Journal of Medical Sciences 44, no.4 (2014): 656 - 660.
MLA AFSHARI Reza,NOMANI Hosein,ZANIANI RIYAHI Fatemeh,NABAVINIA Maryam Sadat,MIRBAGHERI Zohreh,MESHKAT Mojtaba,GERAYLI Sina,ROSTAMI Sina,MESHKAT Zahra Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. Turkish Journal of Medical Sciences, vol.44, no.4, 2014, ss.656 - 660.
AMA AFSHARI R,NOMANI H,ZANIANI RIYAHI F,NABAVINIA M,MIRBAGHERI Z,MESHKAT M,GERAYLI S,ROSTAMI S,MESHKAT Z Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. Turkish Journal of Medical Sciences. 2014; 44(4): 656 - 660.
Vancouver AFSHARI R,NOMANI H,ZANIANI RIYAHI F,NABAVINIA M,MIRBAGHERI Z,MESHKAT M,GERAYLI S,ROSTAMI S,MESHKAT Z Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran. Turkish Journal of Medical Sciences. 2014; 44(4): 656 - 660.
IEEE AFSHARI R,NOMANI H,ZANIANI RIYAHI F,NABAVINIA M,MIRBAGHERI Z,MESHKAT M,GERAYLI S,ROSTAMI S,MESHKAT Z "Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran." Turkish Journal of Medical Sciences, 44, ss.656 - 660, 2014.
ISNAD AFSHARI, Reza vd. "Genotype distribution of hepatitis C virus in Khorasan Razavi Province, Iran". Turkish Journal of Medical Sciences 44/4 (2014), 656-660.