The aim of the present study is to investigate the validation of the local thermal equilibrium and uniform pressure approach assumptions employed for analyzing heat and mass transfer in the adsorbent beds. An experimental setup consists of an adsorbent bed filled with silica gel particles and a water vessel was designed and constructed such way to measure the local temperature and pressure in different locations inside the bed during the adsorption process. Moreover, the heat and mass transfer equations based on uniform pressure approach and local thermal equilibrium assumptions were solved. The numerical results were compared with the corresponding experimental results and excellent agreement between them was observed. Based on the performed comparisons, two significant remarks for the studied bed were concluded, a) a local thermal equilibrium between solid and water vapor exists, b) the interparticlemass transfer resistance in the bed is negligible and the uniform pressure approach for determination of concentration and temperature distributions inside the bed can be used. Furthermore, the presented experimental results in this study provide valuable data for validation of computational studies for other researchers.